Fbxw15 (NM_199036) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR215379L4V

Lenti ORF particles, Fbxw15 (GFP-tagged) - Mouse F-box and WD-40 domain protein 15 (Fbxw15), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Fbxw15
• Synonyms: Fbxo12J
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_199036
• ORF Size: 1398 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR215379).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_199036.2, NP_950201.2
• RefSeq Size: 1520 bp
• RefSeq ORF: 1401 bp
• Locus ID: 382105
• UniProt ID: L7N1X6
• Cytogenetics: 9 F2
• Gene Summary: Substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes KAT7 ubiquitination and subsequent degradation in collaboration with MAP2K1 kinase, leading to reduced histone H3K14 acetylation and increased cell proliferation.[UniProtKB/Swiss-Prot Function]