Slc9b2 (NM_178877) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR208700L3V

Lenti ORF particles, Slc9b2 (Myc-DDK-tagged) - Mouse Na+/H+ exchanger domain containing 2 (Nhedc2), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Slc9b2
• Synonyms: C80638; nha-oc; NHA2; nhaoc; NHE10; Nhedc2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_178877
• ORF Size: 1641 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR208700).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_178877.6, NP_849208.4
• RefSeq Size: 2243 bp
• RefSeq ORF: 1644 bp
• Locus ID: 97086
• UniProt ID: Q5BKR2
• Cytogenetics: 3 G3
• Gene Summary: Na(+)/H(+) antiporter that extrudes Na(+) or Li(+) in exchange for external protons across the membrane (PubMed:18508966, PubMed:17988971). Contributes to the regulation of intracellular pH, sodium homeostasis, and cell volume. Plays an important role for insulin secretion and clathrin-mediated endocytosis in beta-cells (PubMed:23720317). Involved in sperm motility and fertility (PubMed:27010853). It is controversial whether SLC9B2 plays a role in osteoclast differentiation (PubMed:17988971) or not (PubMed:20441802, PubMed:22985540).[UniProtKB/Swiss-Prot Function]