Vapa (NM_013933) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR203158L3V

Lenti ORF particles, Vapa (Myc-DDK-tagged) - Mouse vesicle-associated membrane protein, associated protein A (Vapa), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Vapa
• Synonyms: 33kDa; VAP33
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_013933
• ORF Size: 747 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR203158).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013933.3, NP_038961.2
• RefSeq Size: 1658 bp
• RefSeq ORF: 750 bp
• Locus ID: 30960
• UniProt ID: Q9WV55
• Cytogenetics: 17 E1.1
• Gene Summary: Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With OSBPL3, may regulate ER morphology. May play a role in vesicle trafficking.[UniProtKB/Swiss-Prot Function]