PIP5KI gamma (PIP5K1C) (NM_001300849) Human Untagged Clone

CAT#: SC337267

PIP5K1C (untagged) - Human phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (PIP5K1C), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIP5K1C
• Synonyms: LCCS3; PIP5K-GAMMA; PIP5K1-gamma; PIP5Kgamma
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001300849, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGCTGGAGGTACCGGACGAGGCGGAGAGCGCTGAGGCGGGGGCCGTGCCCTCGGAGGCGGCGTGGG
  CGGCAGAGAGCGGGGCGGCGGCAGGTTTGGCTCAGAAGAAGGCGGCCCCAACAGAGGTTCTGTCCATGAC
  GGCACAGCCGGGCCCTGGCCATGGGAAGAAGTTGGGCCATCGAGGTGTGGACGCATCCGGCGAAACCACC
  TACAAGAAGACCACCTCCTCCACCCTGAAGGGTGCCATCCAGCTGGGCATCGGCTACACCGTGGGCCACC
  TGAGCTCCAAGCCCGAACGCGACGTGCTCATGCAGGACTTCTACGTGGTGGAGAGCATCTTCTTCCCCAG
  CGAAGGCAGCAACCTCACCCCCGCCCACCACTTCCAGGACTTCCGCTTCAAGACCTATGCACCTGTCGCC
  TTCCGCTACTTCCGGGAGCTCTTTGGGATCCGGCCAGATGATTACTTGTACTCCCTGTGCAATGAGCCGC
  TGATCGAGCTGTCCAACCCGGGCGCCAGTGGCTCCCTCTTCTACGTCACCAGCGACGACGAGTTCATCAT
  CAAGACCGTCATGCACAAGGAGGCCGAGTTCCTGCAGAAGCTGCTCCCTGGCTACTACATGAACCTCAAC
  CAGAACCCGCGGACGCTGCTGCCCAAGTTCTATGGGCTGTACTGCGTGCAGTCGGGGGGCAAGAACATCC
  GCGTCGTGGTCATGAACAACATCCTGCCCCGCGTGGTCAAGATGCACCTCAAGTTCGACCTCAAGGGCTC
  CACCTACAAGCGGCGCGCCAGCAAGAAGGAGAAGGAGAAGAGCTTCCCCACCTACAAGGACCTGGACTTC
  ATGCAGGACATGCCCGAGGGGCTCCTGCTGGACGCCGACACCTTCAGCGCCCTGGTCAAGACGCTGCAGC
  GGGACTGCCTGGTCCTGGAAAGTTTCAAGATCATGGACTACAGCCTGCTGCTGGGCGTGCACAACATCGA
  CCAGCACGAGCGCGAGCGGCAGGCGCAGGGCGCCCAGAGCACCTCAGATGAGAAGCGGCCTGTGGGCCAG
  AAGGCGCTCTACTCCACGGCCATGGAGTCCATCCAGGGTGGCGCCGCGCGCGGGGAGGCCATCGAATCGG
  ATGACACGATGGGCGGGATCCCCGCTGTGAACGGCCGCGGGGAGCGGCTGCTGCTGCACATTGGCATCAT
  CGACATCCTGCAGTCCTACAGGTTCATCAAGAAACTGGAGCACACCTGGAAGGCCCTCGTCCACGATGGG
  GACACGGTGTCCGTCCACCGCCCCAGCTTCTATGCCGAGCGCTTTTTCAAGTTCATGAGCAACACGGTCT
  TTCGGAAGAACTCCTCCCTGAAGTCCTCGCCCTCCAAGAAGGGGCGCGGCGGAGCCTTGCTAGCTGTGAA
  ACCGCTGGGGCCCACCGCTGCCTTCTCGGCCAGCCAGATCCCTAGCGAGCGGGAGGAGGCCCAGTACGAC
  CTGCGGGGGGCCCGCAGCTACCCCACGCTGGAGGACGAAGGCCGGCCCGACCTCCTGCCCTGCACGCCAC
  CTTCTTTCGAAGAAGCCACTACAGCCTCCATTGCCACGACTCTGTCATCCACATCCCTCTCCATTCCTGA
  GCGGTCCCCCTCGGAGACGTCGGAGCAGCCGCGGTACAGGCGGCGCACACAGTCGTCTGGACAGGATGGC
  AGGCCGCAGGAGGAGCCACCCGCGGAAGAGGATCTGCAGCAGATTACAGTGCAGGTGGAGCCTGCGTGCA
  GCGTGGAGATTGTGGTCCCCAAAGAGGAGGACGCAGGGGTGGAGGCTTCCCCGGCCGGTGCCTCTGCTGC
  TGTTGAAGTAGAAACTGCCAGCCAGGCCTCAGACGAGGAGGGCGCACCTGCCAGCCAGGCCTCGGACGAG
  GAGGACGCGCCCGCCACCGACATCTACTTTTTCACGGATGGGAGGTACTGGATTTACTCTCCCCGCCATC
  GCCGACTGCGGGCCGTGACGCTGAGCGCCTCGGGGACTGTAAGTGACCGCAGCCGGCCACCCTGGGGAGA
  AGGGGCAGTGCCCCTCGGGCAGCAGGGAGCCGCAGGTCCCCGGCCGGAAGCTCAGTGTCTGACGTCAGTT
  GTTTTCCAGAAGGGCTTTGGGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001300849
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001300849.1, NP_001287778.1
• RefSeq Size: 3035 bp
• RefSeq ORF: 2124 bp
• Locus ID: 23396
• UniProt ID: O60331
• Cytogenetics: 19p13.3
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis, Fc gamma R-mediated phagocytosis, Focal adhesion, Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, Regulation of actin cytoskeleton
• Gene Summary: This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010]
  Transcript Variant: This variant (3, also known as PIPKIgamma_v5) encodes the longest isoform (3, also known as PIPKIgamma_i5).