PAQR6 (NM_001272109) Human Untagged Clone

CAT#: SC333217

PAQR6 (untagged) - Homo sapiens progestin and adipoQ receptor family member VI (PAQR6), transcript variant 8

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PAQR6
• Synonyms: PRdelta
• Vector: pCMV6-Entry
• Sequence Data:
  Fully Sequenced ORF

  >SC333217 representing NM_001272109.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  ATGGCTACCATCTCTTCTGCGCGCTGCTCACTGGCTTCCTCTTCGCCTCCCACCTGCCTGAAAGGCTGG
  CACCAGGACGCTTTGATTACATCGGCCACAGCCACCAGTTATTCCACATCTGTGCAGTGCTGGGCACCC
  ACTTCCAGCTGGAGGCAGTGCTGGCTGATATGGGATCACGCAGAGCCTGGCTGGCCACACAGGAACCTG
  CCCTGGGCCTGGCAGGCACAGTGGCCACACTGGTCTTGGCTGCAGCTGGGAACCTACTCATTATTGCTG
  CTTTCACAGCCACCCTGCTTCGGGCCCCCAGTACATGCCCTCTGCTGCAGGGTGGCCCACTGGAGGGGG
  GTACCCAGGCCAAACAACAGTGAGGCCCCATCCCTGACCCTGTCCTGGAGGGGGCAGAGGCCAGGCCCC
  AGTGCTGACGAGGAGCCCAGATTTGGGCCTAATCAGGTGGGGACGCATCTCAGCCTGGAACCAACAGGG
  GCTGAGGAGAGAGGGCACAGGAGAGAGGGCAGAGAAGAGGAGGGGTGTCTAGGGGGACTGGCAGAGTGT
  GAGAGGGACCGTGAGGGGGCTCTTGATGGGAGTGGAAGAAGTGCTGAGGGTCTGAGAGGGGAGATGCAT
  GCGTGTCCAGGCTGA
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001272109
• Insert Size: 636 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001272109.1
• RefSeq Size: 1961 bp
• RefSeq ORF: 636 bp
• Locus ID: 79957
• UniProt ID: Q6TCH4
• Cytogenetics: 1q22
• Protein Families: Druggable Genome, Transmembrane
• MW: 23.2 kDa
• Gene Summary: Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432, PubMed:23161870). Seems to act through a G(s) mediated pathway (PubMed:23161870). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). May be involved in regulating rapid P4 signaling in the nervous system (PubMed:23763432). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23763432, PubMed:23161870).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (8) has multiple differences and initiates translation at an alternate start codon, compared to variant 1. Variants 8 through 12 encode the same isoform (7), which has a distinct N-terminus and is shorter, compared to isoform 1.