CACNA1G (NM_001256331) Human Untagged Clone

CAT#: SC332354

CACNA1G (untagged) - Homo sapiens calcium channel, voltage-dependent, T type, alpha 1G subunit (CACNA1G), transcript variant 23

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CACNA1G
• Synonyms: Ca(V)T.1; Cav3.1; NBR13; SCA42; SCA42ND
• Vector: pCMV6-Entry
• Sequence Data:
  Fully Sequenced ORF

  >SC332354 representing NM_001256331.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  ATGGACGAGGAGGAGGATGGAGCGGGCGCCGAGGAGTCGGGACAGCCCCGGAGCTTCATGCGGCTCAAC
  GACCTGTCGGGGGCCGGGGGCCGGCCGGGGCCGGGGTCAGCAGAAAAGGACCCGGGCAGCGCGGACTCC
  GAGGCGGAGGGGCTGCCGTACCCGGCGCTGGCCCCGGTGGTTTTCTTCTACTTGAGCCAGGACAGCCGC
  CCGCGGAGCTGGTGTCTCCGCACGGTCTGTAACCCCTGGTTTGAGCGCATCAGCATGTTGGTCATCCTT
  CTCAACTGCGTGACCCTGGGCATGTTCCGGCCATGCGAGGACATCGCCTGTGACTCCCAGCGCTGCCGG
  ATCCTGCAGGCCTTTGATGACTTCATCTTTGCCTTCTTTGCCGTGGAGATGGTGGTGAAGATGGTGGCC
  TTGGGCATCTTTGGGAAAAAGTGTTACCTGGGAGACACTTGGAACCGGCTTGACTTTTTCATCGTCATC
  GCAGGGATGCTGGAGTACTCGCTGGACCTGCAGAACGTCAGCTTCTCAGCTGTCAGGACAGTCCGTGTG
  CTGCGACCGCTCAGGGCCATTAACCGGGTGCCCAGCATGCGCATCCTTGTCACGTTGCTGCTGGATACG
  CTGCCCATGCTGGGCAACGTCCTGCTGCTCTGCTTCTTCGTCTTCTTCATCTTCGGCATCGTCGGCGTC
  CAGCTGTGGGCAGGGCTGCTTCGGAACCGATGCTTCCTACCTGAGAATTTCAGCCTCCCCCTGAGCGTG
  GACCTGGAGCGCTATTACCAGACAGAGAACGAGGATGAGAGCCCCTTCATCTGCTCCCAGCCACGCGAG
  AACGGCATGCGGTCCTGCAGAAGCGTGCCCACGCTGCGCGGGGACGGGGGCGGTGGCCCACCTTGCGGT
  CTGGACTATGAGGCCTACAACAGCTCCAGCAACACCACCTGTGTCAACTGGAACCAGTACTACACCAAC
  TGCTCAGCGGGGGAGCACAACCCCTTCAAGGGCGCCATCAACTTTGACAACATTGGCTATGCCTGGATC
  GCCATCTTCCAGGTCATCACGCTGGAGGGCTGGGTCGACATCATGTACTTTGTGATGGATGCTCATTCC
  TTCTACAATTTCATCTACTTCATCCTCCTCATCATCGTGGGCTCCTTCTTCATGATCAACCTGTGCCTG
  GTGGTGATTGCCACGCAGTTCTCAGAGACCAAGCAGCGGGAAAGCCAGCTGATGCGGGAGCAGCGTGTG
  CGGTTCCTGTCCAACGCCAGCACCCTGGCTAGCTTCTCTGAGCCCGGCAGCTGCTATGAGGAGCTGCTC
  AAGTACCTGGTGTACATCCTTCGTAAGGCAGCCCGCAGGCTGGCTCAGGTCTCTCGGGCAGCAGGTGTG
  CGGGTTGGGCTGCTCAGCAGCCCAGCACCCCTCGGGGGCCAGGAGACCCAGCCCAGCAGCAGCTGCTCT
  CGCTCCCACCGCCGCCTATCCGTCCACCACCTGGTGCACCACCACCACCACCATCACCACCACTACCAC
  CTGGGCAATGGGACGCTCAGGGCCCCCCGGGCCAGCCCGGAGATCCAGGACAGGGATGCCAATGGGTCC
  CGCCGGCTCATGCTGCCACCACCCTCGACGCCTGCCCTCTCCGGGGCCCCCCCTGGTGGCGCAGAGTCT
  GTGCACAGCTTCTACCATGCCGACTGCCACTTAGAGCCAGTCCGCTGCCAGGCGCCCCCTCCCAGGTCC
  CCATCTGAGGCATCCGGCAGGACTGTGGGCAGCGGGAAGGTGTATCCCACCGTGCACACCAGCCCTCCA
  CCGGAGACGCTGAAGGAGAAGGCACTAGTAGAGGTGGCTGCCAGCTCTGGGCCCCCAACCCTCACCAGC
  CTCAACATCCCACCCGGGCCCTACAGCTCCATGCACAAGCTGCTGGAGACACAGAGTACAGGTGCCTGC
  CAAAGCTCTTGCAAGATCTCCAGCCCTTGCTTGAAAGCAGACAGTGGAGCCTGTGGTCCAGACAGCTGC
  CCCTACTGTGCCCGGGCCGGGGCAGGGGAGGTGGAGCTCGCCGACCGTGAAATGCCTGACTCAGACAGC
  GAGGCAGTTTATGAGTTCACACAGGATGCCCAGCACAGCGACCTCCGGGACCCCCACAGCCGGCGGCAA
  CGGAGCCTGGGCCCAGATGCAGAGCCCAGCTCTGTGCTGGCCTTCTGGAGGCTAATCTGTGACACCTTC
  CGAAAGATTGTGGACAGCAAGTACTTTGGCCGGGGAATCATGATCGCCATCCTGGTCAACACACTCAGC
  ATGGGCATCGAATACCACGAGCAGCCCGAGGAGCTTACCAACGCCCTAGAAATCAGCAACATCGTCTTC
  ACCAGCCTCTTTGCCCTGGAGATGCTGCTGAAGCTGCTTGTGTATGGTCCCTTTGGCTACATCAAGAAT
  CCCTACAACATCTTCGATGGTGTCATTGTGGTCATCAGCGTGTGGGAGATCGTGGGCCAGCAGGGGGGC
  GGCCTGTCGGTGCTGCGGACCTTCCGCCTGATGCGTGTGCTGAAGCTGGTGCGCTTCCTGCCGGCGCTG
  CAGCGGCAGCTGGTGGTGCTCATGAAGACCATGGACAACGTGGCCACCTTCTGCATGCTGCTTATGCTC
  TTCATCTTCATCTTCAGCATCCTGGGCATGCATCTCTTCGGCTGCAAGTTTGCCTCTGAGCGGGATGGG
  GACACCCTGCCAGACCGGAAGAATTTTGACTCCTTGCTCTGGGCCATCGTCACTGTCTTTCAGATCCTG
  ACCCAGGAGGACTGGAACAAAGTCCTCTACAATGGTATGGCCTCCACGTCGTCCTGGGCGGCCCTTTAT
  TTCATTGCCCTCATGACCTTCGGCAACTACGTGCTCTTCAATTTGCTGGTCGCCATTCTGGTGGAGGGC
  TTCCAGGCGGAGGAAATCAGCAAACGGGAAGATGCGAGTGGACAGTTAAGCTGTATTCAGCTGCCTGTC
  GACTCCCAGGGGGGAGATGCCAACAAGTCCGAATCAGAGCCCGATTTCTTCTCACCCAGCCTGGATGGT
  GATGGGGACAGGAAGAAGTGCTTGGCCTTGGTGTCCCTGGGAGAGCACCCGGAGCTGCGGAAGAGCCTG
  CTGCCGCCTCTCATCATCCACACGGCCGCCACACCCATGTCGCTGCCCAAGAGCACCAGCACGGGCCTG
  GGCGAGGCGCTGGGCCCTGCGTCGCGCCGCACCAGCAGCAGCGGGTCGGCAGAGCCTGGGGCGGCCCAC
  GAGATGAAGTCACCGCCCAGCGCCCGCAGCTCTCCGCACAGCCCCTGGAGCGCTGCAAGCAGCTGGACC
  AGCAGGCGCTCCAGCCGGAACAGCCTCGGCCGTGCACCCAGCCTGAAGCGGAGAAGCCCAAGTGGAGAG
  CGGCGGTCCCTGTTGTCGGGAGAAGGCCAGGAGAGCCAGGATGAAGAGGAGAGCTCAGAAGAGGAGCGG
  GCCAGCCCTGCGGGCAGTGACCATCGCCACAGGGGGTCCCTGGAGCGGGAGGCCAAGAGTTCCTTTGAC
  CTGCCAGACACACTGCAGGTGCCAGGGCTGCATCGCACTGCCAGTGGCCGAGGGTCTGCTTCTGAGCAC
  CAGGACTGCAATGGCAAGTCGGCTTCAGGGCGCCTGGCCCGGGCCCTGCGGCCTGATGACCCCCCACTG
  GATGGGGATGACGCCGATGACGAGGGCAACCTGAGCAAAGGGGAACGGGTCCGCGCGTGGATCCGAGCC
  CGACTCCCTGCCTGCTGCCTCGAGCGAGACTCCTGGTCAGCCTACATCTTCCCTCCTCAGTCCAGGTTC
  CGCCTCCTGTGTCACCGGATCATCACCCACAAGATGTTCGACCACGTGGTCCTTGTCATCATCTTCCTT
  AACTGCATCACCATCGCCATGGAGCGCCCCAAAATTGACCCCCACAGCGCTGAACGCATCTTCCTGACC
  CTCTCCAATTACATCTTCACCGCAGTCTTTCTGGCTGAAATGACAGTGAAGGTGGTGGCACTGGGCTGG
  TGCTTCGGGGAGCAGGCGTACCTGCGGAGCAGTTGGAACGTGCTGGACGGGCTGTTGGTGCTCATCTCC
  GTCATCGACATTCTGGTGTCCATGGTCTCTGACAGCGGCACCAAGATCCTGGGCATGCTGAGGGTGCTG
  CGGCTGCTGCGGACCCTGCGCCCGCTCAGGGTGATCAGCCGGGCGCAGGGGCTGAAGCTGGTGGTGGAG
  ACGCTGATGTCCTCACTGAAACCCATCGGCAACATTGTAGTCATCTGCTGTGCCTTCTTCATCATTTTC
  GGCATCTTGGGGGTGCAGCTCTTCAAAGGGAAGTTTTTCGTGTGCCAGGGCGAGGATACCAGGAACATC
  ACCAATAAATCGGACTGTGCCGAGGCCAGTTACCGGTGGGTCCGGCACAAGTACAACTTTGACAACCTT
  GGCCAGGCCCTGATGTCCCTGTTCGTTTTGGCCTCCAAGGATGGTTGGGTGGACATCATGTACGATGGG
  CTGGATGCTGTGGGCGTGGACCAGCAGAACTTCCACAAGTGTCGGCAGCACCAGGAGGAAGAGGAGGCC
  CGGCGGCGGGAGGAGAAGCGCCTACGAAGACTGGAGAAAAAGAGAAGGAAAGCCCAGTGCAAACCTTAC
  TACTCCGACTACTCCCGCTTCCGGCTCCTCGTCCACCACTTGTGCACCAGCCACTACCTGGACCTCTTC
  ATCACAGGTGTCATCGGGCTGAACGTGGTCACCATGGCCATGGAGCACTACCAGCAGCCCCAGATTCTG
  GATGAGGCTCTGAAGATCTGCAACTACATCTTCACTGTCATCTTTGTCTTGGAGTCAGTTTTCAAACTT
  GTGGCCTTTGGTTTCCGTCGGTTCTTCCAGGACAGGTGGAACCAGCTGGACCTGGCCATTGTGCTGCTG
  TCCATCATGGGCATCACGCTGGAGGAAATCGAGGTCAACGCCTCGCTGCCCATCAACCCCACCATCATC
  CGCATCATGAGGGTGCTGCGCATTGCCCGAGTGCTGAAGCTGCTGAAGATGGCTGTGGGCATGCGGGCG
  CTGCTGGACACGGTGATGCAGGCCCTGCCCCAGGTGGGGAACCTGGGACTTCTCTTCATGTTGTTGTTT
  TTCATCTTTGCAGCTCTGGGCGTGGAGCTCTTTGGAGACCTGGAGTGTGACGAGACACACCCCTGTGAG
  GGCCTGGGCCGTCATGCCACCTTTCGGAACTTTGGCATGGCCTTCCTAACCCTCTTCCGAGTCTCCACA
  GGTGACAATTGGAATGGCATTATGAAGGACACCCTCCGGGACTGTGACCAGGAGTCCACCTGCTACAAC
  ACGGTCATCTCGCCTATCTACTTTGTGTCCTTCGTGCTGACGGCCCAGTTCGTGCTAGTCAACGTGGTG
  ATCGCCGTGCTGATGAAGCACCTGGAGGAGAGCAACAAGGAGGCCAAGGAGGAGGCCGAGCTAGAGGCT
  GAGCTGGAGCTGGAGATGAAGACCCTCAGCCCCCAGCCCCACTCGCCACTGGGCAGCCCCTTCCTCTGG
  CCTGGGGTCGAGGGCCCCGACAGCCCCGACAGCCCCAAGCCTGGGGCTCTGCACCCAGCGGCCCACGCG
  AGATCAGCCTCCCACTTTTCCCTGGAGCACCCCACGATGCAGCCCCACCCCACGGAGCTGCCAGGACCA
  GACTTACTGACTGTGCGGAAGTCTGGGGTCAGCCGAACGCACTCTCTGCCCAATGACAGCTACATGTGT
  CGGCATGGGAGCACTGCCGAGGGGCCCCTGGGACACAGGGGCTGGGGGCTCCCCAAAGCTCAGTCAGGC
  TCCGTCTTGTCCGTTCACTCCCAGCCAGCAGATACCAGCTACATCCTGCAGCTTCCCAAAGATGCACCT
  CATCTGCTCCAGCCCCACAGCGCCCCAACCTGGGGCACCATCCCCAAACTGCCCCCACCAGGACGCTCC
  CCTTTGGCTCAGAGGCCACTCAGGCGCCAGGCAGCAATAAGGACTGACTCCTTGGACGTTCAGGGTCTG
  GGCAGCCGGGAAGACCTGCTGGCAGAGGTGAGTGGGCCCTCCCCGCCCCTGGCCCGGGCCTACTCTTTC
  TGGGGCCAGTCAAGTACCCAGGCACAGCAGCACTCCCGCAGCCACAGCAAGATCTCCAAGCACATGACC
  CCGCCAGCCCCTTGCCCAGGCCCAGAACCCAACTGGGGCAAGGGCCCTCCAGAGACCAGAAGCAGCTTA
  GAGTTGGACACGGAGCTGAGCTGGATTTCAGGAGACCTCCTGCCCCCTGGCGGCCAGGAGGAGCCCCCA
  TCCCCACGGGACCTGAAGAAGTGCTACAGCGTGGAGGCCCAGAGCTGCCAGCGCCGGCCTACGTCCTGG
  CTGGATGAGCAGAGGAGACACTCTATCGCCGTCAGCTGCCTGGACAGCGGCTCCCAACCCCACCTGGGC
  ACAGACCCCTCTAACCTTGGGGGCCAGCCTCTTGGGGGGCCTGGGAGCCGGCCCAAGAAAAAACTCAGC
  CCGCCTAGTATCACCATAGACCCCCCCGAGAGCCAAGGTCCTCGGACCCCGCCCAGCCCTGGTATCTGC
  CTCCGGAGGAGGGCTCCGTCCAGCGACTCCAAGGATCCCTTGGCCTCTGGCCCCCCTGACAGCATGGCT
  GCCTCGCCCTCCCCAAAGAAAGATGTGCTGAGTCTCTCCGGTTTATCCTCTGACCCAGCAGACCTGGAC
  CCCTGA
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001256331
• Insert Size: 6699 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001256331.1
• RefSeq Size: 7829 bp
• RefSeq ORF: 6699 bp
• Locus ID: 8913
• UniProt ID: O43497
• Cytogenetics: 17q21.33
• Protein Families: Druggable Genome, Ion Channels: Calcium, Transmembrane
• Protein Pathways: Calcium signaling pathway, MAPK signaling pathway, Type II diabetes mellitus
• MW: 247 kDa
• Gene Summary: Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]
  Transcript Variant: This variant (23) lacks a segment and three exons in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (23) lacks three internal segments, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.