KCTD1 (NM_001142730) Human Untagged Clone

CAT#: SC326263

KCTD1 (untagged)-Human potassium channel tetramerisation domain containing 1 (KCTD1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCTD1
• Synonyms: C18orf5
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001142730, the custom clone sequence may differ by one or more nucleotides
  ATGGCGAGAATGCCTGGCAGCGGGGACTGTAACACCAGCGCGGGCGGCAGCGCCAGCGCT
  GCCGCCGCCGCCGCCGAGAACAATGGGGAGCGGGGCGAGGGCGAGCGCGGCGCGGGGGGC
  CGCGGCCGCCGCCACAGCCGTCCGCACTACTGCAGCGCGGGCGAGGAGGAGGAGGAAGAG
  GAGGAGGAGGACGAGATCCAGGAGGTGCAGATAACGGGGGACGAGGAGGAGGAGGAGGAC
  GGAGGTGGGGGGCTGGAGGAGGACGAGGAGGAGGAGGAAGAGGAGGAGATGGGGCTGGAC
  TGGGACGAGCCCCTGGAGCCCGAGGACTCGGCCGGGGAGGAGCTGGAGCCCGAGCCGGTC
  CATATGATCAATATGGACCAGAGCGCCGCGCTGGAGCCCGAGGCGCCGCCGCGACTGCTG
  GCGCCCCGGGCCCGCGGTGGGCCGCCCGGGGACGGCTCCGAGCTGGACCCCGACGTGCTG
  CAGCGCCCCGAGCGGGCCCGGCTGAGCGAGAACACCCGGCTGGCCACCCGCTACGCCGTG
  CGCATCTTCCGGGAGTACCTGAGCGAGAAGGCGCAGAGCCCGGACTTCGAGACCATGGAC
  AAGGGGGCGCTGTGCCGCGTGCTGCGCTCCTTCTATGCCGAGGCCCGCTCCAAAAGCGGC
  CAGCTCTACAGCAAGTCGTCGCTCATCAGCATCCGCAGCTCCCTCAACCGCTACCTCAAT
  GAGCCCCCGTACTGCCGCACGCTCGACCTCACCAAGGACCCCGAGCTGCGCAGCGCCAAC
  CTGACGCTGGCCGCGGTCATCCGCAAGCTCGAGGAGCAGGGCGCCGGGCCGGTGGTGCAG
  AAGCAAGCCATCACGCGCGCCGACCTGCGCAAGCTGTACACCTCCAGCGTCTTCAGCACC
  AACACGCCCTTCGGGCTGCTCAACAAGGTCTGGTTCGAGACGTGCATGTACTTCTGTACC
  CGCGGCCGCGAGAACCAGCGTGAGTTGGAGGAGGACTCTTTTGGGCTGGCCATGGACGAG
  GACGGTCGCAAGTTCGTCTACTTCAAGTCCCTCGGGCCCTACCACAAGTCGCGCTCGTCG
  TCGTGGAGCAAGAAGCGCGCCGAGAGCAGCGACGAGGAGAACTTGCCCCGCATGTATGAG
  ACGGGCACCGAGTTCTGCCCCTACGCCAGCTTCGTCAAGTACCTGTCGAAACGCAACCCT
  CTCTGCAAGGCGTTCTTCCAGCGGCCCCGGGACCACTGCAGCGAGGGCGATGTGACCTGG
  TACGAGAACAAAGCCATCGGCAAGAACTTGCTAGGCACTCGGATGCAGATGCTCTCCAAG
  GCGGCCAAGCTCTCCAAGACCTACACCAACCACTGCATCGGCGCCGTCTCCATCGCCACG
  CTCAACAGCATCGCGGGCATTGGCACCAAGCTGGGCTCGCCCGCCCCGCAGGGCTGCTAC
  GCCGAGGCTCTGAACGGGGCGGCACGGCACCACTCCCACCACCCCCCCACCCATCCCTCC
  CACCACCACCGCCCCCAGCCGCCCTCGCTGGGGAACACTTACATCCTCCCCAAAGACAGC
  CAGGTCGGGCCCGACGTGAAATCCGAGGCTGCGCCCAAGCGCGCCCTGTACGAGTCTGTG
  TTCGGGTCGGGGGAAATCTGCGGCCCCACTTCCCCCAAAAGACTTTGTATCCGCCCCTCG
  GAGCCTGTGGATGCGGTGGTGGTGGTTTCCGTGAAACACGACCCCCTGCCTCTTCTTCCA
  GAAGCCAATGGGCACAGAAGCACCAATTCTCCCACAATAGTTTCACCTGCTATTGTTTCC
  CCCACCCAGGACAGTCGGCCCAATATGTCAAGACCTCTGATCACTAGATCCCCTGCATCT
  CCACTGAACAACCAAGGCATCCCTACTCCAGCACAACTCACAAAATCCAATGCGCCTGTC
  CACATTGATGTGGGCGGCCACATGTACACCAGCAGCCTGGCCACCCTCACCAAATACCCT
  GAATCCAGAATCGGAAGACTTTTTGATGGTACAGAGCCCATTGTTTTGGACAGTCTCAAA
  CAGCACTATTTCATTGACAGAGATGGACAGATGTTCAGATATATCTTGAATTTTCTACGA
  ACATCCAAACTCCTCATTCCTGATGATTTCAAGGACTACACTTTGTTATATGAAGAGGCA
  AAATATTTTCAGCTTCAGCCCATGTTGTTGGAGATGGAAAGATGGAAGCAGGACAGAGAA
  ACTGGTCGATTTTCAAGGCCCTGTGAGTGCCTCGTCGTGCGTGTGGCCCCAGACCTCGGA
  GAAAGGATCACGCTAAGCGGTGACAAATCCTTGATAGAAGAAGTATTTCCAGAGATCGGC
  GACGTGATGTGTAACTCTGTCAATGCAGGCTGGAATCACGACTCGACGCACGTCATCAGG
  TTTCCACTAAATGGCTACTGTCACCTCAACTCAGTCCAGGTCCTCGAGAGGTTGCAGCAA
  AGAGGATTTGAAATCGTGGGCTCCTGTGGGGGAGGAGTAGACTCGTCCCAGTTCAGCGAA
  TACGTCCTTCGGCGGGAACTGAGGCGGACGCCCCGTGTACCCTCCGTCATCCGGATAAAG
  CAAGAGCCTCTGGAC
  
• Restriction Sites: Please inquire
• ACCN: NM_001142730
• Insert Size: 3438 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001142730.1, NP_001136202.1
• RefSeq Size: 3438 bp
• RefSeq ORF: 3438 bp
• Locus ID: 284252
• UniProt ID: Q719H9
• Cytogenetics: 18q11.2
• Protein Families: Ion Channels: Other
• Gene Summary: This gene encodes a protein containing a BTB (Broad-complex, tramtrack and bric a brac), also known as a POZ (POxvirus and zinc finger) protein-protein interaction domain. The encoded protein negatively regulates the AP-2 family of transcription factors and the Wnt signaling pathway. A mechanism for the modulation of Wnt signaling has been proposed in which the encoded protein enhances ubiquitination and degradation of the beta-catenin protein. Mutations in this gene have been identified in Scalp-ear-nipple (SEN) syndrome. [provided by RefSeq, May 2017]
  Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (b). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.