Ubiquinol Cytochrome C Reductase Core Protein I (UQCRC1) (NM_003365) Human Untagged Clone

CAT#: SC324450

UQCRC1 (untagged)-Human ubiquinol-cytochrome c reductase core protein I (UQCRC1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Ubiquinol Cytochrome C Reductase Core Protein I
• Synonyms: D3S3191; QCR1; UQCR1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003365.2 CGACTGCAGCTGGAAGATGGCGGCGTCCGTGGTCTGTCGGGCCGCTACCGCCGGGGCACA
  AGTGCTATTGCGCGCCCGCCGCTCGCCGGCCCTGCTGCGGACGCCAGCCTTGCGGAGTAC
  GGCAACCTTCGCTCAGGCGCTCCAGTTCGTGCCGGAGACGCAGGTTAGCCTGCTGGACAA
  CGGCCTGCGTGTGGCCTCCGAGCAGTCCTCTCAGCCCACTTGCACGGTGGGAGTGTGGAT
  TGATGTTGGCAGCCGTTTTGAGACTGAGAAGAATAATGGGGCAGGCTACTTTTTGGAGCA
  TCTGGCTTTCAAGGGAACAAAGAATCGGCCTGGCAGTGCCCTGGAGAAGGAGGTGGAGAG
  CATGGGGGCCCATCTTAATGCCTACAGCACCCGGGAGCACACAGCTTACTACATCAAGGC
  GCTGTCCAAGGATCTGCCGAAAGCTGTGGAGCTCCTGGGTGACATTGTGCAGAACTGTAG
  TCTGGAAGACTCACAGATTGAGAAGGAACGTGATGTGATCCTGCGGGAGATGCAGGAGAA
  TGATGCATCTATGCGAGATGTGGTCTTTAACTACCTGCATGCCACAGCATTCCAGGGCAC
  ACCTCTAGCCCAGGCTGTGGAGGGGCCCAGTGAGAATGTCAGGAAGCTGTCTCGTGCAGA
  CTTGACCGAGTACCTCAGCACACATTACAAGGCCCCTCGAATGGTGCTGGCAGCAGCTGG
  AGGAGTGGAGCACCAGCAACTGTTAGACCTCGCCCAGAAGCACCTCGGTGGCATCCCATG
  GACATATGCAGAGGACGCTGTGCCCACTCTTACTCCATGCCGCTTCACTGGCAGTGAGAT
  CCGCCACCGTGATGATGCTCTACCTTTTGCCCACGTGGCCATTGCAGTAGAGGGTCCTGG
  CTGGGCCAGCCCGGACAATGTGGCCTTGCAAGTGGCCAATGCCATCATCGGCCACTATGA
  CTGCACTTATGGTGGTGGCGTGCACCTGTCCAGCCCACTGGCTTCAGGTGCTGTGGCCAA
  CAAGCTATGCCAGAGTTTCCAGACCTTCAGCATCTGCTATGCAGAGACGGGCTTGCTGGG
  TGCACACTTTGTCTGTGACCGAATGAAAATCGATGACATGATGTTCGTCCTGCAAGGGCA
  GTGGATGCGCCTGTGTACCAGTGCCACGGAGAGTGAGGTGGCCCGGGGCAAAAACATCCT
  CAGAAATGCCCTGGTATCTCATCTAGATGGCACTACTCCTGTGTGTGAGGACATCGGACG
  CAGCCTCCTGACCTATGGCCGCCGCATCCCCCTGGCTGAATGGGAAAGCCGGATTGCGGA
  GGTGGATGCCAGTGTGGTACGTGAGATCTGCTCCAAGTACATCTATGACCAGTGCCCAGC
  AGTGGCTGGATATGGCCCCATTGAGCAGCTCCCAGACTACAACCGGATCCGTAGCGGCAT
  GTTCTGGCTGCGCTTCTAGGCGGGAAGCCTATGTAAGCAAGAGGGCAGGGCCGGGGTTTG
  TGGTCCCCCCCCCACCACAAACACAGCACTTCGGCTCCTCTAACCTGTGCCACAGGTGAC
  CACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_003365
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003365.2, NP_003356.2
• RefSeq Size: 1636 bp
• RefSeq ORF: 1443 bp
• Locus ID: 7384
• UniProt ID: P31930
• Cytogenetics: 3p21.31
• Domains: Peptidase_M16, Peptidase_M16_C
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
• Gene Summary: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.[UniProtKB/Swiss-Prot Function]