GDI1 (NM_001493) Human Untagged Clone

CAT#: SC324140

GDI1 (untagged)-Human GDP dissociation inhibitor 1 (GDI1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GDI1
• Synonyms: 1A; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001493.1 GTGCGGTGGCGGCGGCGGCGGTGGCGGCGGCGACTGCTGCGGTGAAGGAGGAGGAGGAGC
  CGAGCGGGCGCTGGCACCGAGGCCTGACCATGGACGAGGAATACGATGTGATCGTGCTGG
  GGACCGGTCTCACCGAATGCATCCTGTCGGGCATCATGTCTGTGAACGGGAAGAAGGTGC
  TGCACATGGACCGGAACCCCTACTACGGGGGCGAGAGCTCCTCCATCACACCCCTGGAGG
  AGCTGTATAAGCGTTTTCAGTTGCTGGAGGGGCCCCCTGAGTCGATGGGCCGAGGCCGAG
  ACTGGAATGTTGACCTGATTCCCAAATTCCTCATGGCTAACGGGCAGCTGGTAAAGATGC
  TACTGTATACAGAGGTGACTCGCTACCTGGACTTCAAGGTGGTGGAGGGCAGCTTTGTCT
  ACAAGGGGGGCAAGATCTACAAAGTGCCGTCCACTGAGACTGAGGCCTTGGCTTCCAATC
  TGATGGGCATGTTTGAGAAACGGCGCTTCCGCAAGTTCCTGGTGTTTGTGGCAAACTTCG
  ATGAGAATGACCCCAAGACCTTTGAGGGCGTTGACCCCCAGACTACCAGCATGCGTGACG
  TCTACCGGAAGTTTGATCTGGGCCAGGATGTCATCGATTTCACTGGCCATGCCCTGGCGC
  TCTACCGCACTGATGACTACCTGGACCAGCCCTGCCTTGAGACCGTCAACCGCATCAAGT
  TGTACAGTGAGTCCCTGGCCCGGTATGGCAAGAGCCCATATTTATACCCGCTCTACGGCT
  TGGGCGAGCTGCCCCAGGGTTTTGCAAGATTGAGTGCCATCTATGGGGGGACATATATGC
  TGAACAAACCTGTGGATGACATCATCATGGAGAACGGCAAGGTGGTGGGCGTGAAGTCTG
  AGGGAGAGGTGGCCCGCTGCAAGCAGCTGATCTGTGACCCCAGCTACATCCCGGACCGTG
  TGCGGAAGGCTGGCCAGGTTATCCGCATCATCTGTATCCTTAGCCACCCCATCAAGAACA
  CCAACGACGCCAACTCCTGCCAAATAATCATCCCCCAGAACCAGGTCAACAGGAAGTCAG
  ACATCTACGTGTGCATGATCTCCTATGCACACAACGTGGCGGCCCAGGGCAAGTACATAG
  CTATTGCCAGCACTACTGTGGAGACCACGGACCCTGAAAAGGAGGTGGAGCCGGCTCTGG
  AGCTGTTGGAGCCCATTGACCAGAAGTTTGTGGCTATCAGTGACTTGTATGAGCCCATTG
  ATGATGGTTGTGAGAGCCAGGTGTTCTGTTCCTGCTCCTACGATGCCACCACACACTTTG
  AGACAACCTGCAACGACATCAAAGACATCTACAAACGCATGGCTGGCACGGCCTTTGACT
  TTGAGAACATGAAGCGCAAACAGAACGACGTCTTTGGAGAAGCTGAGCAGTGATTGTGGC
  CGCCCCCAGCCCCTGCTGCCCCAGCCTGTGTCTGTTCTCCTCGAGGGCTCCAGCATCCTC
  TGCTTCCCCCACCACGTTCCCATCACCCACCTCATTGATCCACTGACCAAATCCTTAACC
  CTAGCGATGGCTTGGGAGATGGGGGGTTGGATAGCATCCTCTTTCTTGGCCCTTCCTTAT
  CCTAGGAAAAGAGGGTTCCTCTCCTTGTGTGTGTCTCTTCCCCCCACCCCTAATTCTTCT
  GCTCTGTTTGGGAAGACGTGGAGGAAAAGGTGACTTCTGCCCCCACCGCTCTTACCCCCA
  CTGTAGTGGCCTTTGGAGATGCCCCCACCTCCCCCCCACCAACTCTCGCGTGTTGGAGAG
  AAGGGGCCCTCCCAGCACAAAGTTGCATTCCTCCCCCCTAATTTATTCTAATTTATTAAC
  TTTGACCCACCCTTTCTGAGCCTGCAGCCTTCCCGTGTGGCCTGAGGGCTGTCGAGTGAG
  CTGCCCCAGCCCCTCCCAGCCCTTGCCCAGCCTGGGGGAGTGGGGAAGGCTTGGGCATGG
  CCCCGTTGGAGGTTGATTTGCTGTTTTGTTTCTTGTCTTTGTGTTCTGTGGTACTTGCTG
  AGAGAAAAGAAAAGTGAGCCAAGCAGAAGGAGGTGGGAAAACGGACCCAAACCCCAGTGT
  GCCCTGCCCCATGCCTTTCCTTTAGTGGTGGGAAACCCTTATCTTGCAAAGTGAATGTGT
  CCCCTTCCCCACCCTCTAGTGTATTTCACAGAAAACAAAACCTCCCAATAAAACGGTTGA
  AACCTGAAAAAAAAAAAAAAA
• Restriction Sites: ECoRI-NOT
• ACCN: NM_001493
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001493.1, NP_001484.1
• RefSeq Size: 2225 bp
• RefSeq ORF: 1344 bp
• Locus ID: 2664
• UniProt ID: P31150
• Cytogenetics: Xq28
• Domains: GDI
• Protein Families: Druggable Genome
• Gene Summary: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific cognitive disability. [provided by RefSeq, Jul 2008]