IL22RA1 (NM_021258) Human Untagged Clone

CAT#: SC322566

IL22RA1 (untagged)-Human interleukin 22 receptor, alpha 1 (IL22RA1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL22RA1
• Synonyms: CRF2-9; IL22R; IL22R1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322566 GCAGAGTAGAGGCCAAGGGAGGGCTCTGTGCCAGCCCCGATGAGGACGCTGCTGACCATC
  TTGACTGTGGGATCCCTGGCTGCTCACGCCCCTGAGGACCCCTCGGATCTGCTCCAGCAC
  GTGAAATTCCAGTCCAGCAACTTTGAAAACATCCTGACGTGGGACAGCGGGCCGGAGGGC
  ACCCCAGACACGGTCTACAGCATCGAGTATAAGACGTACGGAGAGAGGGACTGGGTGGCA
  AAGAAGGGCTGTCAGCGGATCACCCGGAAGTCCTGCAACCTGACGGTGGAGACGGGCAAC
  CTCACGGAGCTCTACTATGCCAGGGTCACCGCTGTCAGTGCGGGAGGCCGGTCAGCCACC
  AAGATGACTGACAGGTTCAGCTCTCTGCAGCACACTACCCTCAAGCCACCTGATGTGACC
  TGTATCTCCAAAGTGAGATCGATTCAGATGATTGTTCATCCTACCCCCACGCCCATCCGT
  GCAGGCGATGGCCACCGGCTAACCCTGGAAGACATCTTCCATGACCTGTTCTACCACTTA
  GAGCTCCAGGTCAACCGCACCTACCAAATGCACCTTGGAGGGAAGCAGAGAGAATATGAG
  TTCTTCGGCCTGACCCCTGACACAGAGTTCCTTGGCACCATCATGATTTGCGTTCCCACC
  TGGGCCAAGGAGAGTGCCCCCTACATGTGCCGAGTGAAGACACTGCCAGACCGGACATGG
  ACCTACTCCTTCTCCGGAGCCTTCCTGTTCTCCATGGGCTTCCTCGTCGCAGTACTCTGC
  TACCTGAGCTACAGATATGTCACCAAGCCGCCTGCACCTCCCAACTCCCTGAACGTCCAG
  CGAGTCCTGACTTTCCAGCCGCTGCGCTTCATCCAGGAGCACGTCCTGATCCCTGTCTTT
  GACCTCAGCGGCCCCAGCAGTCTGGCCCAGCCTGTCCAGTACTCCCAGATCAGGGTGTCT
  GGACCCAGGGAGCCTGCAGGAGCTCCACAGCGGCATAGCCTGTCCGAGATCACCTACTTA
  GGGCAGCCAGACATCTCCATCCTCCAGCCCTCCAACGTGCCACCTCCCCAGATCCTCTCC
  CCACTGTCCTATGCCCCAAACGCTGCCCCTGAGGTCGGGCCCCCATCCTATGCACCTCAG
  GTGACCCCCGAAGCTCAATTCCCATTCTACGCCCCACAGGCCATCTCTAAGGTCCAGCCT
  TCCTCCTATGCCCCTCAAGCCACTCCGGACAGCTGGCCTCCCTCCTATGGGGTATGCATG
  GAAGGTTCTGGCAAAGACTCCCCCACTGGGACACTTTCTAGTCCTAAACACCTTAGGCCT
  AAAGGTCAGCTTCAGAAAGAGCCACCAGCTGGAAGCTGCATGTTAGGTGGCCTTTCTCTG
  CAGGAGGTGACCTCCTTGGCTATGGAGGAATCCCAAGAAGCAAAATCATTGCACCAGCCC
  CTGGGGATTTGCACAGACAGAACATCTGACCCAAATGTGCTACACAGTGGGGAGGAAGGG
  ACACCACAGTACCTAAAGGGCCAGCTCCCCCTCCTCTCCTCAGTCCAGATCGAGGGCCAC
  CCCATGTCCCTCCCTTTGCAACCTCCTTCCCGTCCATGTTCCCCCTCGGACCAAGGTCCA
  AGTCCCTGGGGCCTGCTGGAGTCCCTTGTGTGTCCCAAGGATGAAGCCAAGAGCCCAGCC
  CCTGAGACCTCAGACCTGGAGCAGCCCACAGAACTGGATTCTCTTTTCAGAGGCCTGGCC
  CTGACTGTGCAGTGGGAGTCCTGAGGGGAATGGGAAAGGCTTGGTGCTTCCTCCCTGTCC
  CTACCCAGTGTCACATCCTTGGCTGTCAATCCCATGCCTGCCCACGCCACACACTCTGCG
  ATCTGGCCTCAGACGGGTGCCCTTGAGAGAAGCAGAGGGAGTGGCATGCAGGGCCCCTGC
  CATGGGTGCGCTCCTCACCGGAGCAAAGCAGCATGATAAGGACTGCAGCGGGGGAGCTCT
  GGGGAGCAGCTTGTGTAGACAAGCGCGTGCTCGCTGAGCCCTGCAAGGCAGAAATGACAG
  TGCAAGGAGGAAATGCAGGGAAACTCCCGAGGTCCAGAGCCCCACCTCCTAACACCATGG
  ATTCAAAGTGCTCAGGGAATTTGCCTCTCCTTGCCCCATTCCTGGCCAGTTTCACAATCT
  AGCTCGACAGAGCATGAGGCCCCTGCCTCTTCTGTCATTGTTCAAAGGTGGGAAGAGAGC
  CTGGAAAAGAACCAGGCCTGGAAAAGAACCAGAAGGAGGCTGGGCAGAACCAGAACAACC
  TGCACTTCTGCCAAGGCCAGGGCCAGCAGGACGGCAGGACTCTAGGGAGGGGTGTGGCCT
  GCAGCTCATTCCCAGCCAGGGCAACTGCCTGACGTTGCACGATTTCAGCTTCATTCCTCT
  GATAGAACAAAGCGAAATGCAGGTCCACCAGGGAGGGAGACACACAAGCCTTTTCTGCAG
  GCAGGAGTTTCAGACCCTATCCTGAGAATGGGGTTTGAAAGGAAGGTGAGGGCTGTGGCC
  CCTGGACGGGTACAATAACACACTGTACTGATGTCACAACTTTGCAAGCTCTGCCTTGGG
  TTCAGCCCATCTGGGCTCAAATTCCAGCCTCACCACTCACAAGCTGTGTGACTTCAAACA
  AATGAAATCAGTGCCCAGAACCTCGGTTTCCTCATCTGTAATGTGGGGATCATAACACCT
  ACCTCATGGAGTTGTGGTGAAGATGAAATGAAGTCATGTCTTTAAAGTGCTTAATAGTGC
  CTGGTACATGGGCAGTGCCCAATAAACGGTAGCTATTTAAAAAAAAAAAAAAAAAAAAAA
  AAAA
• Restriction Sites: Please inquire
• ACCN: NM_021258
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021258.2, NP_067081.2
• RefSeq Size: 2811 bp
• RefSeq ORF: 1725 bp
• Locus ID: 58985
• UniProt ID: Q8N6P7
• Cytogenetics: 1p36.11
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]