DECR2 (NM_020664) Human Untagged Clone

CAT#: SC322397

DECR2 (untagged)-Human 2,4-dienoyl CoA reductase 2, peroxisomal (DECR2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DECR2
• Synonyms: PDCR; SDR17C1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322397 CCCGGTTCCAGGCGAGTTCGCAGCTGCGCGCCGGGTCCTGGAGGCCGAGGCCGCTCCCGC
  CCGTTGTCCCCGCAGTCCCCGACGGGAGCGCCATGGCCCAGCCGCCGCCCGACGTGGAGG
  GGGACGACTGTCTCCCCGCGTACCGCCACCTCTTCTGCCCGGACCTGCTGCGGGACAAAG
  TGGCCTTCATCACAGGAGGCGGCTCTGGGATTGGGTTCCGGATTGCTGAGATTTTCATGC
  GGCACGGCTGCCATACGGTGATTGCCAGTAGGAGCCTGCCGCGAGTGCTGACGGCCGCCA
  GGAAGCTGGCTGGGGCCACCGGCCGGCGCTGCCTCCCTCTCTCTATGGACGTCCGAGCGC
  CCCCAGCTGTCATGGCCGCCGTGGACCAGGCTCTGAAGGAGTTTGGCAGAATCGACATTC
  TCATTAACTGTGCGGCCGGGAACTTCCTGTGCCCCGCTGGCGCCTTGTCCTTCAACGCCT
  TCAAGACCGTGATGGACATCGATACCAGCGGCACCTTCAATGTGTCTCGTGTGCTCTATG
  AGAAGTTCTTCCGGGACCACGGAGGGGTGATCGTGAACATCACTGCCACCCTGGGGAACC
  GGGGGCAGGCGCTCCAGGTGCATGCAGGCTCCGCCAAGGCCGCTGTGGACGCGATGACGC
  GGCACTTGGCTGTGGAGTGGGGTCCCCAAAACATCCGCGTCAACAGCCTCGCCCCTGGCC
  CCATCAGTGGCACAGAGGGGCTCCGGCGACTGGGTGGCCCTCAAGCCAGCCTGAGCACCA
  AGGTCACTGCCAGCCCGCTGCAGAGGCTGGGGAACAAGACCGAGATCGCCCACAGCGTGC
  TCTACCTGGCCAGCCCTCTGGCTTCCTACGTGACGGGGGCCGTGCTGGTGGCCGATGGCG
  GGGCATGGTTGACGTTCCCAAACGGTGTCAAAGGGCTGCCGGATTTCGCATCCTTCTCTG
  CTAAGCTCTAGGAATCTTCCGGCCGCTGCTTCCTGCCGCCTCACTCAGCCAGGTGGAGAG
  CACCAATCTGAACCAGCAATGCCTGCAGCCCAGCCCCTCCTCTGAACACTCAGCTATTAC
  TGCGCTTTCCCTCCCCACGGCCCCAACTCCAGGGCAGGAGCAACTGGACAGTGGGCCTGG
  CCCGTGGAGCTGCCACGCAGGTGCCTGAGGGCCAGGTGCCACGCAGGTGTCTGAGGACCA
  GGTGCCACGCAGGTGGTGGGGGTACAGACAAGATGCTGGGATGTCCCCTGCCCCATGGTC
  AAGGGTGTCCTGCCTGCCTGGGTCCAGGGCCTGAGGGAGCCACATGGATCCCGAGACTTG
  TGTTCTCTTGGCTGAAAACACTGAGGTGCTCCCATCTGTGCGTGGCCCATGAGCTGGGAT
  GGTCCTCCAGCTGCCCACAAGGTCCGCCCCTCTGTCTCTGCACCACCTGTTTGCATAAAC
  ACACTTTGCTACAATCTTGCTAGTGCGTTTTCTTAAAAGATAATCTATTTACTGTAAAAA
  TAAATTGGACTTTGCAAAAGCTTTTAGAAGGAAAAGAAAGAGGATTAAAGAGAATTGCTG
  GTGATCCTAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_020664
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_020664.3, NP_065715.1
• RefSeq Size: 1599 bp
• RefSeq ORF: 879 bp
• Locus ID: 26063
• UniProt ID: Q9NUI1
• Cytogenetics: 16p13.3
• Domains: adh_short
• Protein Families: Druggable Genome
• Gene Summary: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.[UniProtKB/Swiss-Prot Function]