SNX14 (NM_020468) Human Untagged Clone

CAT#: SC321258

SNX14 (untagged)-Human sorting nexin 14 (SNX14), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SNX14
• Synonyms: RGS-PX2; SCAR20
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_020468.2 GTGGGGCTGGGCCCAGCCGGACGCGACCTCAGCCTGCGGCGGCTAACTGCCGGTAGGCGT
  CTGTGTGCGCCGCCAAGTCGGTGGGGCGGGGACGCGAGGTGTGGATGGGGGGTCGCCTTG
  ACCTCTGCCTCAGCCAGTAGCGCAGTCTCGGCCTCGCCGTTACGGAGATGGTGCCCTGGG
  TGCGGACGATGGGGCAGAAGCTGAAGCAGCGGCTGCGACTGGACGTGGGACGCGAGATCT
  GCCGCCAGTACCCGCTGTTCTGCTTCCTGCTGCTCTGTCTCAGCGCCGCCTCCCTGCTTC
  TTAACAGGTATATTCATATTTTAATGATCTTCTGGTCATTTGTTGCTGGAGTTGTCACAT
  TCTACTGCTCACTAGGACCTGATTCTCTCTTACCAAATATATTCTTCACAATAAAATACA
  AACCCAAGCAGTTAGGACTTCAGGAATTATTTCCTCAAGGTCATAGCTGTGCTGTTTGTG
  GTAAAGTGAAATGTAAACGACATAGGCCTTCTTTGCTACTTGAAAACTACCAGCCATGGC
  TAGACCTGAAAATTTCTTCCAAGGTTGATGCATCTCTCTCAGAGGTGGATATTCCATCTA
  TTATAACCAAGAAACTATTAAAAGCAGCAATGAAGCATATAGAAGTGATAGTTAAAGCCA
  GACAGAAAGTAAAAAATACAGAGTTTTTACAGCAAGCTGCTTTAGAAGAATATGGTCCAG
  AGCTTCATGTTGCTTTGAGAAGTCGAAGAGATGAATTGCACTATTTAAGGAAACTTACTG
  AACTGCTTTTTCCTTATATTTTGCCTCCTAAAGCAACAGACTGCAGATCTCTGACCTTAC
  TTATAAGAGAGATTCTGTCTGGCTCTGTGTTCCTTCCTTCTTTGGATTTCCTAGCTGATC
  CAGATACTGTGAATCATTTGCTTATCATCTTCATAGATGACAGTCCACCTGAAAAAGCAA
  CTGAACCGGCTTCTCCTTTGGTTCCATTCTTGCAGAAATTTGCAGAACCTAGAAATAAAA
  AGCCATCTGTGCTGAAGTTAGAATTGAAGCAAATCAGAGAGCAACAAGATCTTTTATTTC
  GTTTTATGAACTTTCTGAAACAAGAAGGCGCAGTGCACGTGTTGCAGTTTTGTTTGACTG
  TGGAGGAATTTAATGATAGAATTTTACGACCAGAATTATCAAATGATGAAATGCTGTCTC
  TTCATGAAGAATTGCAGAAGATTTATAAAACATACTGTTTGGATGAAAGTATTGACAAAA
  TTAGATTTGATCCCTTCATTGTAGAAGAGATTCAAAGAATTGCTGAAGGCCCATACATAG
  ATGTTGTGAAACTTCAAACTATGAGATGTCTTTTTGAAGCATATGAACATGTTCTTTCCC
  TTTTGGAGAATGTATTTACTCCTATGTTCTGCCATAGTGATGAGTATTTCAGACAACTTT
  TAAGAGGTGCAGAATCACCAACACGCAATTCAAAATTGAACAGGAACACACAGAAAAGGG
  GAGAATCATTTGGAATCAGCAGAATAGGTAGCAAAATTAAAGGAGTATTCAAAAGTACCA
  CAATGGAGGGAGCTATGTTGCCTAATTATGGTGTAGCTGAAGGTGAAGATGATTTTATTG
  AAGAAGGTATTGTTGTAATGGAAGATGATTCTCCAGTGGAGGCTGTGAGCACACCTAATA
  CTCCCCGAAACCTTGCTGCATGGAAAATTAGCATTCCATATGTAGACTTTTTTGAGGATC
  CCTCCTCTGAAAGGAAGGAGAAAAAAGAAAGAATTCCTGTGTTTTGTATTGATGTTGAAA
  GAAATGATAGAAGAGCAGTTGGACACGAGCCTGAACATTGGTCTGTCTATAGAAGATATC
  TTGAATTCTATGTACTTGAATCAAAACTAACAGAATTTCATGGTGCATTTCCTGATGCCC
  AGCTTCCTTCTAAGAGGATCATTGGCCCCAAAAATTATGAATTCTTAAAGTCAAAGAGGG
  AAGAGTTCCAAGAATATCTACAGAAACTTCTGCAGCATCCAGAACTGAGTAATAGTCAAC
  TTCTGGCAGACTTTCTTTCCCCTAATGGTGGGGAAACACAATTTCTTGATAAGATACTAC
  CAGATGTAAATCTTGGGAAAATTATAAAATCTGTTCCTGGAAAACTAATGAAAGAGAAAG
  GTCAGCATTTGGAACCTTTTATCATGAATTTCATTAATTCTTGTGAGTCTCCAAAGCCTA
  AACCAAGTAGACCAGAACTGACCATTCTCAGCCCTACTTCAGAAAACAACAAGAAGCTTT
  TCAATGATCTGTTTAAAAATAATGCAAACCGTGCTGAAAATACAGAGAGAAAGCAAAATC
  AGAATTATTTTATGGAGGTGATGACTGTAGAAGGAGTCTATGATTACCTGATGTATGTAG
  GACGGGTAGTTTTCCAGGTTCCTGACTGGCTTCATCATCTCTTAATGGGAACTCGAATCC
  TCTTTAAAAACACCCTGGAAATGTATACTGATTACTATCTTCAGTGTAAACTAGAACAGC
  TATTTCAGGAGCACCGTTTGGTCTCACTCATAACACTTCTCAGAGATGCTATATTCTGTG
  AAAACACTGAACCTCGCTCTCTCCAAGATAAGCAAAAAGGAGCAAAACAGACTTTTGAAG
  AAATGATGAATTACATTCCAGATCTGTTAGTCAAGTGTATTGGTGAAGAAACCAAGTATG
  AAAGCATCAGACTTCTGTTTGATGGCTTACAGCAACCAGTACTCAACAAGCAGCTGACTT
  ATGTTTTATTGGACATTGTGATACAGGAACTGTTTCCAGAGCTCAATAAGGTACAAAAGG
  AAGTTACCTCTGTGACATCTTGGATGTAAACACTTGGATTTGGTATAGAATAACCCATTG
  AAATTTCTGCTGTGCGAGGGTGGTAGAAATTTACTTTTTTGGGTATATTCTTATATATAT
  TATGTACATCGCTGTCTGAAATTTTAGTTATTTTTTGTTTTTAATAAAGACTAACACAAA
  CTTAATGATTAAAAGTGAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_020468
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_020468.2, NP_065201.1
• RefSeq Size: 3350 bp
• RefSeq ORF: 2682 bp
• Locus ID: 57231
• UniProt ID: Q9Y5W7
• Cytogenetics: 6q14.3
• Domains: RGS, PX, PXA
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family have a phox (PX) phosphoinositide binding domain and are involved in intracellular trafficking. The encoded protein also contains a regulator of G protein signaling (RGS) domain. Regulator of G protein signaling family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. Alternate splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (2) lacks in-frame segments of the coding region compared to variant 1. It encodes a shorter isoform (b), compared to isoform a.