POLR1C (NM_203290) Human Untagged Clone

CAT#: SC320288

POLR1C (untagged)-Human polymerase (RNA) I polypeptide C, 30kDa (POLR1C)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: POLR1C
• Synonyms: AC40; HLD11; RPA5; RPA39; RPA40; RPAC1; RPC40; TCS3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_203290.1 GGCACGAGGGAGAGATTGAAGATGGCGGCTTCTCAGGCGGTGGAGGAAATGCGGAGCCGC
  GTGGTTCTGGGGGAGTTTGGGGTTCGCAATGTCCATACTACTGACTTTCCCGGTAACTAT
  TCCGGTTATGATGATGCCTGGGACCAGGACCGCTTCGAGAAGAATTTCCGTGTGGATGTA
  GTACACATGGATGAAAACTCACTGGAGTTTGACATGGTGGGAATTGACGCAGCCATTGCC
  AATGCTTTTCGACGAATTCTGCTAGCTGAGGTGCCAACTATGGCTGTGGAGAAGGTCCTG
  GTGTACAATAATACATCCATTGTTCAGGATGAGATTCTTGCTCACCGTCTGGGGCTCATT
  CCCATTCATGCTGATCCCCGTCTTTTTGAGTATCGGAACCAAGGAGATGAAGAAGGCACA
  GAGATAGATACTCTACAGTTTCGTCTCCAGGTCAGATGCACTCGGAACCCCCATGCTGCT
  AAAGATTCCTCTGACCCCAACGAACTGTACGTGAACCACAAAGTGTATACCAGGCATATG
  ACATGGATCCCCCTGGGGAACCAGGCTGATCTCTTTCCAGAGGGCACTATCCGACCAGTG
  CATGATGATATCCTCATCGCTCAGCTGCGGCCTGGCCAAGAAATTGACCTGCTCATGCAC
  TGTGTCAAGGGCATTGGCAAAGATCATGCCAAGTTTTCACCAGTGGCAACAGCCAGTTAC
  AGGCTCCTGCCAGACATCACCCTGCTTGAGCCCGTGGAAGGGGAGGCAGCTGAGGAGTTG
  AGCAGGTGCTTCTCACCTGGTGTTATTGAGGTGCAGGAAGTCCAAGGTAAAAAGGTGGCC
  AGAGTTGCCAACCCCCGGCTGGATACCTTCAGCAGAGAAATCTTCCGGAATGAGAAGCTA
  AAGAAGGTTGTGAGGCTTGCCCGGGTTCGAGATCATTATATCTTCTCTGTTGAGTCAACG
  GGGGTGTTGCCACCAGATGTGCTGGTGAGTGAAGCCATCAAAGTACTGATGGGGAAGTGC
  CGGCGCTTCTTGGATGAACTAGATGCGGTTCAGATGGACTGAGCTTGGATGCTTCTGAGG
  CAAGCTGAAGCTTTGGGTTCTGACTGACCCACCCTACAGGACTGCTGAACAGAGAGCCCA
  GTGTGACTAGGGATCCTGAGTTTTCTGGGACAATTCCAGCTTTAATCAATACATTTTGTT
  AAATGTGCCATAAAATGAGACTTTTTACGCCTTTATAAGGCCTTAGATGTAAATAAACTC
  ACCCAAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_203290
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_203290.1, NP_976035.1
• RefSeq Size: 1322 bp
• RefSeq ORF: 1041 bp
• Locus ID: 9533
• UniProt ID: O15160
• Cytogenetics: 6p21.1
• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors
• Protein Pathways: Cytosolic DNA-sensing pathway, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase
• Gene Summary: The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
  Transcript Variant: This variant (1) encodes the longest isoform (1).