DHRS4 (NM_021004) Human Untagged Clone

CAT#: SC319893

DHRS4 (untagged)-Human dehydrogenase/reductase (SDR family) member 4 (DHRS4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DHRS4
• Synonyms: CR; NRDR; PHCR; PSCD; SCAD-SRL; SDR-SRL; SDR25C1; SDR25C2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021004.2 GCTGGAAGGAGTGGAACCCAGACTTGCTGGTCTGATCCATGCACATGGCCAGGCTGCTAG
  GCCTCTGTGCCTGGGCACGGAAGTCGGTGCGGTTGGCCAGCTCCAGGATGACCCGCCGGG
  ACCCGCTCACAAATAAGGTGGCCCTGGTAACGGCCTCCACCGACGGGATCGGCTTCGCCA
  TCGCCCGGCGTTTGGCCCAGGACAGGGCCCACGTGGTCGTCAGCAGCCGGAAGCAGCAGA
  ATGTGGACCAGGCGGTGGCCACGCTGCAGGGGGAGGGGCTGAGCGTGACGGGCACTGTGT
  GCCATGTGGGGAAGGCGGAGGACCGGGAGCGGCTGGTGGCCATGGCTGTGAAGCTTCATG
  GAGGTATCGATATCCTAGTCTCCAATGCTGCTGTCAACCCTTTCTTTGGAAGCCTAATGG
  ATGTCACCGAGGAGGTGTGGGACAAGACTCTGGACATTAATGTGAAGGCCCCAGCCCTGA
  TGACAAAGGCAGTGGTGCCAGAAATGGAGAAACGAGGAGGCGGCTCAGTGGTGATCGTGT
  CTTCCATAGCAGCCTTCAGTCCATCTCCTGGCTTCAGTCCTTACAATGTCAGTAAAACAG
  CCTTGCTGGGCCTCAACAATACCCTGGCCATAGAGCTGGCCCCAAGGAACATTAGGGTGA
  ACTGCCTGCACCTGGACTTATCAAGACTAGCTTCAGCAGGATGCTCTGGATGGACAAGGA
  AAAAGAGGAAAGCATGAAAGAAACCCTGCGGATAAGAAGGTTAGGCGAGCCAGAGGATTG
  TGCTGGCATCGTGTCTTTCCTGTGCTCTGAAGATGCCAGCTACATCACTGGGGAAACAGT
  GGTGGTGGGTGGAGGAACCCCGTCCCGCCTCTGAGGACCGGGAGACAGCCCACAGGCCAG
  AGTTGGGCTCTAGCTCCTGGTGCTGTTCCCGCATTCACCCACTGGCCTTTCCCACCTCTG
  CTCACCTTACTGTTCACCTCATAAAATCAGTTCTGCCCTGTGAAAAGATCCAGCCTTCCC
  TGCCGTCAAGGTGGCGTCTTACTCGGGATTTCTGCTGTTGTTGTGGCCTTGGGTAAAGGC
  CTCCCCTGAGAACACAGGACAGGCCTGCTGACAAGGCTGAGTCTACCTTGGCAAAGACCA
  AGATATTTTTTCCCGGGCCACTGGGGAATCTGAGGGGTGATGGGAGAGAAGGAACCTGGA
  GTGGAAGGAGCAGAGTTGCAAATTAACAACTTGCAAATGAGGTGCAAATAAAATGCAGAT
  GATTGCGCGAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_021004
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021004.2, NP_066284.2
• RefSeq Size: 1289 bp
• RefSeq ORF: 837 bp
• Locus ID: 10901
• UniProt ID: Q9BTZ2
• Cytogenetics: 14q11.2
• Domains: adh_short
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Retinol metabolism
• Gene Summary: Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).