CLIC2 (NM_001289) Human Untagged Clone

CAT#: SC319747

CLIC2 (untagged)-Human chloride intracellular channel 2 (CLIC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CLIC2
• Synonyms: CLCNL2; CLIC2b; MRXS32; XAP121
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001289.4 TCTACAAGCTAGACGGTCTTCTTAAAGCACCAACATTACTTGAGTCTTTGGATAAAATTG
  AGAAAAGAGTCTACAAGTATTGTGGACTCTACAGGAGGCAGGAGGCTGACAACTGGCAGT
  AAAGACAAAGATGTCAGGCCTGCGGCCCGGCACTCAAGTGGACCCTGAGATTGAGCTTTT
  TGTAAAGGCTGGAAGTGATGGAGAGAGTATTGGAAACTGTCCCTTTTGCCAACGCCTTTT
  CATGATCCTCTGGCTTAAAGGAGTTAAATTTAATGTGACAACTGTTGACATGACCAGAAA
  GCCTGAAGAACTAAAGGACTTAGCCCCAGGTACCAATCCTCCGTTCCTGGTGTATAACAA
  GGAGTTGAAAACAGACTTCATTAAAATTGAGGAGTTTTTAGAACAAACCCTGGCTCCTCC
  AAGGTACCCTCACCTGAGTCCCAAGTACAAGGAGTCTTTTGATGTGGGCTGTAACCTCTT
  TGCCAAGTTTTCTGCATACATTAAGAATACACAAAAGGAGGCAAATAAGAATTTTGAAAA
  ATCTCTGCTCAAAGAATTCAAGCGTCTGGATGACTACTTAAACACCCCACTTCTGGATGA
  AATTGATCCAGACAGTGCTGAGGAACCCCCAGTTTCCAGAAGACTATTCTTGGATGGGGA
  CCAGCTAACACTGGCTGATTGTAGCTTGTTACCCAAGCTGAACATTATTAAAGTTGCTGC
  CAAGAAATATCGTGACTTTGACATTCCAGCAGAATTCTCAGGAGTCTGGCGTTATCTCCA
  CAATGCCTATGCCCGTGAAGAATTTACCCACACGTGTCCTGAAGACAAAGAAATTGAAAA
  TACTTACGCAAATGTGGCTAAACAGAAGAGTTAGGAGAGCTCTTACAGGAGAAAAGGCTA
  TATTTGTGATCAGATTTTACTTATTGACATATTAGAAAGGTTTTTGCAAATAAGAATATG
  AAAAATACTGTTTCTTCTATCCAACTCTCTTATGAAAAGGAACTCTGTATTTTCTATTAG
  CCATAAATAATCTGTCCACTGTATTTTACAGGTCTTCATACTTTTACTTAATTTTCTTTA
  TCTGTATGGCAAACCACTGCAATCCTGAATGACATGGAAAGCATCACAATCTTTTGCCCT
  TTGCTTGAATTCCTGGAATGCATACATATAAGCTAAACAGATGTCTGCAGTTATAAATGT
  CATAAGTAGAGGTACAATCTCACCCTGCTCCTTAGAAACATTTCCATATAAATCGCTAAA
  ATAATTTCACATTTTTGTTAGTTTAATATATACATGAGTTTATTTCTGATATAAATAATA
  AATACAGAGAGTGAGCATATCAGAGAGGCAAATTCTTAAAGAATGATTTTTAAAATCAGC
  TCTAGGAAGAGCTCAAGATCAATTGGTCATAGAACAGCATTTGACGCCTAGAACTATGAC
  CACCTCATGGTCAGAGATGAGAATGTAGCCTTTGTGACCAGATTATATTATTTTTAAATG
  AAGAAGCACTCATTAAATAAAACATAATTTTAAAAAACAATATAAGAAACAAAGTCAACT
  GGATCTTTTATTCACAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_001289
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001289.4, NP_001280.3
• RefSeq Size: 2702 bp
• RefSeq ORF: 744 bp
• Locus ID: 1193
• UniProt ID: O15247
• Cytogenetics: Xq28
• Protein Families: Druggable Genome, Ion Channels: Other
• Gene Summary: This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein plays a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]