CLIC2 (NM_001289) Human Untagged Clone

CAT#: SC119325

CLIC2 (untagged)-Human chloride intracellular channel 2 (CLIC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CLIC2
• Synonyms: CLCNL2; CLIC2b; MRXS32; XAP121
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119325 sequence for NM_001289 edited (data generated by NextGen Sequencing)
  ATGTCAGGCCTGCGGCCCGGCACTCAAGTGGACCCTGAGATTGAGCTTTTTGTAAAGGCT
  GGAAGTGATGGAGAGAGTATTGGAAACTGTCCCTTTTGCCAACGCCTTTTCATGATCCTC
  TGGCTTAAAGGAGTTAAATTTAATGTGACAACTGTTGACATGACCAGAAAGCCTGAAGAA
  CTAAAGGACTTAGCCCCAGGTACCAATCCTCCGTTCCTGGTGTATAACAAGGAGTTGAAA
  ACAGACTTCATTAAAATTGAGGAGTTTTTAGAACAAACCCTGGCTCCTCCAAGGTACCCT
  CACCTGAGTCCCAAGTACAAGGAGTCTTTTGATGTGGGCTGTAACCTCTTTGCCAAGTTT
  TCTGCATACATTAAGAATACACAAAAGGAGGCAAATAAGAATTTTGAAAAATCTCTGCTC
  AAAGAATTCAAGCGTCTGGATGACTACTTAAACACCCCACTTCTGGATGAAATTGATCCA
  GACAGTGCTGAGGAACCCCCAGTTTCCAGAAGACTATTCTTGGATGGGGACCAGCTAACA
  CTGGCTGATTGTAGCTTGTTACCCAAGCTGAACATTATTAAAGTTGCTGCCAAGAAATAT
  CGTGACTTTGACATTCCAGCAGAATTCTCAGGAGTCTGGCGTTATCTCCACAATGCCTAT
  GCCCGTGAAGAATTTACCCACACGTGTCCTGAAGACAAAGAAATTGAAAATACTTACGCA
  AATGTGGCTAAACAGAAGAGTTAG
  
  Clone variation with respect to NM_001289.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001289 unedited
  GGGTCAGAATTTGTATACGACTCATATAGGGCGGCCGCGATTCGGCACGAGGGATTTCAA
  GAGCTGCACTTAAGCATCTAGAATTTTCTGCGTCACACCTCTTGAGAGAAGAGACTGGCT
  CCAGGTCTGACTCAGTCCACTACAAGCTAGACGGTCTTCTTAAAGCACCAACATTACTTG
  AGTCTTTGGATAAAATTGAGAAAAGAGTCTACAAGTATTGTGGACTCTACAGGAGGCAGG
  AGGCTGACAACTGGCAGTAAAGACAAAGATGTCAGGCCTGCGGCCCGGCACTCAAGTGGA
  CCCTGAGATTGAGCTTTTTGTAAAGGCTGGAAGTGATGGAGAGAGTATTGGAAACTGTCC
  CTTTTGCCAACGCCTTTTCATGATCCTCTGGCTTAAAGGAGTTAAATTTAATGTGACAAC
  TGTTGACATGACCAGAAAGCCTGAAGAACTAAAGGACTTAGCCCCAGGTACCAATCCTCC
  GTTCCTGGTGTATAACAAGGAGTTGAAAACAGACTTCATTAAAATTGAGGAGTTTTTAGA
  ACAAACCCTGGCTCCTCCAAGGTACCCTCACCTGAGTCCCAAGTACAAGGAGTCTTTTGA
  TGTGGGCTGTAACCTCTTTGCCAAGTTTTCTGCATACATTAAGAATACACAAAAGGAGGC
  AAATAAGAATTTTGAAAAATCTCTGCTCAAAGAATTCAAGCGTCTGGATGACTACTTAAA
  CACCCCACTTCTGGATGAAATTGATCCAGACAGTGCTGAGGGAACCCCAGTTTCCAGAAG
  ACTATTCTTGGATGGNGACCAGCTAACACTGGCTGATTGTAGCTTGTTACCCAAGCTGAA
  CATTATTAAAGTTGCTGCCAAGAAATATCGTGACTTTGACATTCCAGCAGAANTCTCAGG
  AGTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001289 unedited
  TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAAGGTTTTTAAAAT
  TTATTTTTTAAATGTATAATGGGCACATAATTGTACATATATATGGGATACAATGTGGTG
  TTTCAATGCATGTACACACAGTATAATGATCAAATAGGCGTAATTACCATATCCACCACT
  ATAAACATTTGTTATTTCTTTGTGGTGACATTTAAAAACCTGCTTTTCTAGCTATCTTGA
  AATACATGCTACATTATTATTTGCTATAGTCACCCTACTGTGGTGAATACCAAAATTTAT
  TCTTCCTAGGTGTAACTTTATACCCATTGACCAACATCTTTCAGTGCCTCTGCCTTCTTT
  CTCTCCCTAGCCCCTGGTAACCACGATTCTACCCTCTACTTGTGTGAGATCAACTTTTTA
  AAATTCCACATATGAGTGAGATCAACTTTTTAAAATTCCACATATGAGTGAGATCATGTG
  GTGTTTGTCTTTCTGTGCCTGGCTTATTTCATTTAACATTTCAAATGTATTCTATCAATT
  GTAACTTGCTAGTGCATTGCATGTATTCTGAAATATACTGATGACAGGATGTATCTCAAA
  GATTATCAACATGATTGCATTTCTCTGCCACCTAACCATACACTATACATTTATCTTGAC
  TCTATGGTTTTCAAGGACAGTACTTTGAGTTTGCTCATTGCCTTACTTTTTTTTGAACCT
  ATTAAAACGCTACTTCATTTCAATTTTATCTAAACTCCACCCTTCCCCAAAGCCTAANAT
  ATTTTCCCTTTTTTGAAGCTGCACTTAATGCTGGGTTTCTCCTTTGAGGAACCAAGAATA
  AGTTCACCTTCTGTTTCCAGATTGGATGATTTAAGAGAACTTTACAAGTGATTCGAAACC
  CATAGAATGAACTTTTACCTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001289
• Insert Size: 2800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001289.4, NP_001280.3
• RefSeq Size: 2702 bp
• RefSeq ORF: 744 bp
• Locus ID: 1193
• UniProt ID: O15247
• Cytogenetics: Xq28
• Protein Families: Druggable Genome, Ion Channels: Other
• Gene Summary: This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein plays a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]