GLIS2 (NM_032575) Human Untagged Clone
CAT#: SC317889
GLIS2 (untagged)-Human GLIS family zinc finger 2 (GLIS2)
"NM_032575" in other vectors (4)
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | GLIS2 |
Synonyms | NKL; NPHP7 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_032575 edited
ATGCACTCCCTGGACGAGCCGCTCGACCTGAAGCTGAGTATCACCAAGCTCCGGGCGGCA AGAGAGAAGCGGGAGAGGACGCTGGGTGTGGTCCGGCCCCGTGCTCTGCACAGGGAGCTG GGCCTGGTGGATGACAGCCCCACACCTGGCTCTCCAGGCTCCCCGCCCTCAGGCTTCCTG CTGAACTCCAAGTTCCCCGAGAAGGTGGAGGGACGCTTTTCAGCAGCCCCTCTCGTGGAC CTCAGCCTGTCACCACCATCTGGGCTGGACTCCCCCAATGGCAGCAGCTCGCTGTCCCCC GAGCGCCAGGGCAACGGGGACCTGCCTCCAGTGCCCAGTGCCTCGGACTTCCAGCCACTG CGCTATTTGGATGGTGTCCCCAGCTCCTTCCAGTTCTTCCTGCCCCTCGGCTCCGGGGGG GCCCTGCACCTGCCTGCCTCCTCCTTCCTTACCCCTCCCAAGGACAAGTGCCTCTCGCCA GACCTGCCCCTGCCCAAGCAGCTGGTGTGTCGCTGGGCCAAGTGTAACCAGCTCTTTGAG CTCCTGCAAGACCTGGTGGACCATGTCAACGATTACCATGTCAAGCCCGAGAAGGATGCG GGGTACTGCTGCCACTGGGAGGGCTGCGCCCGCCATGGCCGAGGTTTCAACGCCAGGTAC AAGATGCTCATCCACATCCGCACACACACCAACGAGAAGCCACACCGCTGTCCGACCTGC AGCAAGAGCTTCTCCCGCCTGGAGAACCTGAAGATCCACAACCGGTCGCACACAGGTGAG AAGCCCTACGTCTGCCCCTACGAGGGCTGCAACAAGCGCTATTCCAACTCCAGTGACCGC TTTAAGCACACGCGCACCCACTATGTGGACAAGCCCTACTACTGCAAGATGCCCGGCTGC CACAAGCGCTACACGGACCCCAGCTCACTGCGCAAGCACATCAAGGCCCATGGCCACTTT GTGTCCCACGAGCAGCAAGAGCTCCTGCAGCTGCGCCCACCCCCCAAGCCGCCACTGCCC GCCCCCGACGGCGGCCCCTATGTCAGTGGGGCCCAGATCATCATCCCCAACCCAGCTGCC CTCTTTGGAGGCCCTGGCCTGCCCGGCTTACCCCTACCCCTGGCCCCCGGCCCCCTTGAC CTCAGTGCCCTGGCCTGTGGCAACGGTGGGGGCAGTGGGGGTGGGGGGGGCATGGGCCCT GGGCTGCCAGGCCCCGTCCTGCCTCTCAATCTGGCCAAGAACCCGCTGCTGCCCTCGCCC TTTGGGGCTGGCGGACTGGGCTTGCCTGTGGTCTCCCTCCTTGCTGGCGCAGCTGGTGGC AAGGCCGAGGGGGAGAAGGGGCGTGGGTCGGTGCCCACCAGGGCCCTGGGCATGGAGGGC CACAAGACGCCCCTTGAAAGGACGGAGAGCAGCTGCTCCCGGCCAAGCCCCGATGGACTC CCCCTGCTGCCAGGCACCGTGCTGGACCTGTCCACGGGCGTCAACTCAGCTGCCAGCAGC CCAGAGGCGTTGGCCCCTGGCTGGGTGGTCATCCCGCCGGGCTCGGTGCTGCTCAAACCG GCTGTGGTGAACTGA |
Restriction Sites | Please inquire |
ACCN | NM_032575 |
Insert Size | 1600 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_032575.2, NP_115964.2 |
RefSeq Size | 3705 bp |
RefSeq ORF | 1575 bp |
Locus ID | 84662 |
UniProt ID | Q9BZE0 |
Cytogenetics | 16p13.3 |
Domains | zf-C2H2 |
Protein Families | ES Cell Differentiation/IPS |
Gene Summary | This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq, Jan 2010] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC223616 | GLIS2 (Myc-DDK-tagged)-Human GLIS family zinc finger 2 (GLIS2) |
USD 488.00 |
|
RC223616L3 | Lenti ORF clone of Human GLIS family zinc finger 2 (GLIS2), Myc-DDK-tagged |
USD 788.00 |
|
RC223616L4 | Lenti ORF clone of Human GLIS family zinc finger 2 (GLIS2), mGFP tagged |
USD 788.00 |
|
RG223616 | GLIS2 (tGFP-tagged) - Human GLIS family zinc finger 2 (GLIS2) |
USD 688.00 |
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