DPP6 (NM_001039350) Human Untagged Clone

CAT#: SC310894

DPP6 (untagged)-Human dipeptidyl-peptidase 6 (DPP6), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DPP6
• Synonyms: DPL1; DPPX; MRD33; VF2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001039350 edited
  GCGCCGAGCTCGGTGGACACGCGCGCAGTCAGAGCTGCCTCTCGCCCTCGCTAGCTGGGC
  TCGCAGCCTCTTCCTCCCTCCCTGGCTCCTGGCTTTTTGTTTAAAGCAACACCCACCCTC
  CATCCAGGCTTTTTTTCTTTCTTTCTTTATTGGTAGCGGCCAAAAAGAGTTGATTGCTAT
  TGGGATCCGCTGAGTAAAGACACGGGCAGGGGTGCGCGGAGGTGAGAAAACTGAAGACCT
  GGAAGATTTTTTTTTCCTTCAAAAACCCGTTTCCATCCAGTCTTCAGCCAGTCCAGTCTA
  CTTTAATCCTCACCAGGACAATGGATTAAGTTTCTCTTCCCTGGACCAGAAGTCGGGTTC
  GGACTTGGGGCAAAATGAAGGAAAAGGCCATGATCAAGACCGCTAAGATGCAGGGGAACG
  TGATGGAGCTGGTGGGGAGTAACCCTCCGCAGAGGAATTGGAAAGGAATAGCAATTGCAC
  TGCTTGTCATTCTGGTCATCTGCTCCTTGATCGTCACCTCGGTCATACTTCTGACACCAG
  CGGAAGATAATAGTCTGTCTCAAAAGAAGAAGGTCACTGTAGAAGATCTCTTCAGTGAAG
  ACTTCAAAATTCATGACCCCGAGGCTAAGTGGATAAGTGATACAGAATTCATCTACAGAG
  AACAGAAAGGAACAGTGAGACTGTGGAATGTTGAAACAAATACTTCTACTGTCTTAATAG
  AAGGCAAAAAAATTGAATCATTAAGAGCCATCAGATATGAAATATCTCCAGATAGAGAGT
  ATGCACTTTTTTCATACAATGTGGAACCCATATATCAACACTCGTATACTGGATATTATG
  TCCTGAGCAAAATTCCTCATGGGGATCCTCAAAGTCTGGACCCACCAGAAGTCAGCAATG
  CAAAACTTCAGTATGCAGGATGGGGCCCTAAAGGCCAACAGCTGATATTTATTTTTGAAA
  ACAATATCTACTACTGTGCACATGTCGGGAAACAGGCCATCCGTGTGGTCTCCACTGGCA
  AGGAAGGTGTGATTTACAATGGCCTCAGTGACTGGCTGTATGAAGAGGAGATTTTGAAGA
  CACACATCGCACACTGGTGGTCTCCGGATGGCACGAGACTCGCCTACGCCGCCATCAATG
  ATTCCCGTGTCCCCATCATGGAGCTCCCAACTTACACCGGCTCCATCTACCCCACCGTGA
  AGCCCTACCACTATCCCAAGGCTGGAAGTGAGAACCCCAGCATTTCCCTACACGTTATTG
  GCTTAAATGGACCCACCCATGATCTGGAGATGATGCCGCCTGATGATCCACGGATGAGGG
  AGTACTACATCACCATGGTGAAGTGGGCCACCAGCACCAAGGTCGCCGTGACCTGGCTGA
  ACCGGGCGCAGAACGTGTCCATCCTCACCCTCTGCGACGCCACCACGGGGGTCTGCACGA
  AGAAACACGAGGATGAAAGTGAGGCCTGGCTCCACAGACAGAATGAAGAACCTGTGTTCT
  CCAAGGATGGCCGAAAGTTTTTCTTCATCAGAGCCATCCCCCAGGGAGGACGAGGGAAAT
  TCTATCACATCACGGTGTCCTCGTCCCAGCCCAACAGCAGCAACGACAACATCCAGTCCA
  TCACCTCCGGGGACTGGGACGTGACCAAGATCCTAGCCTACGATGAGAAGGGGAATAAGA
  TCTACTTCCTGAGCACGGAGGACCTGCCTCGGAGACGACAACTCTACAGTGCCAACACGG
  TGGGCAACTTCAACAGGCAGTGCCTCTCCTGTGACCTGGTTGAGAACTGCACCTACTTCA
  GCGCTTCCTTCAGCCATAGCATGGACTTCTTCCTGCTCAAGTGCGAAGGTCCTGGTGTTC
  CTATGGTGACGGTGCACAACACAACAGATAAGAAAAAAATGTTTGACCTAGAAACAAATG
  AACATGTCAAGAAGGCCATAAATGACCGACAGATGCCTAAAGTGGAATACAGGGACATTG
  AGATTGATGATTACAACCTGCCCATGCAGATACTGAAGCCAGCAACCTTCACCGACACCA
  CCCACTACCCTCTGCTCCTGGTGGTGGATGGCACCCCGGGCAGCCAGAGTGTGGCTGAGA
  AGTTCGAGGTGAGCTGGGAGACGGTGATGGTGAGCAGCCACGGCGCGGTGGTGGTAAAGT
  GTGACGGCCGTGGCAGCGGCTTCCAAGGGACCAAGCTCCTGCACGAAGTGAGGCGGCGGC
  TGGGCTTGCTGGAGGAGAAGGACCAGATGGAGGCCGTGCGGACGATGCTGAAGGAGCAGT
  ACATTGACAGGACGCGCGTGGCCGTGTTTGGGAAGGATTACGGTGGCTACCTGAGCACCT
  ACATCCTCCCAGCAAAGGGAGAAAATCAAGGCCAGACATTCACCTGCGGCTCTGCTCTCT
  CTCCAATAACAGACTTCAAACTCTATGCCTCTGCGTTTTCCGAGAGGTACTTGGGCCTCC
  ATGGACTTGACAACAGAGCATACGAGATGACCAAGGTAGCCCATCGAGTCTCCGCGCTGG
  AAGAACAGCAGTTCCTGATCATTCATCCCACTGCCGATGAAAAAATTCATTTCCAGCACA
  CAGCAGAACTCATTACACAACTAATTAGGGGAAAGGCTAATTACAGCTTACAGATTTACC
  CGGACGAAAGCCATTACTTTACCAGCTCCAGCCTCAAACAGCATCTGTACCGGTCCATCA
  TCAACTTCTTCGTGGAATGCTTCAGGATCCAGGACAAACTGCTGACAGTCACAGCGAAAG
  AGGACGAGGAGGAGGACTAAGCTCAGGTCGCTCTAAGCACAAACGTGGCTCTTTCTACAA
  CCAGATGCAACCGAGGGATTTCCCTGCCCTCCCTCTTCCCTCGGAGGGGCGGGGCGGGGC
  GGGGCCGGGTGTTCCATAGCATGTGTGTCTCGGATGCGGAAGGCAGTTTTGCTTGGGAAA
  CAAGCTCCTTCCCCGGGGTCATCACTCACGGCCTCCATGGCACCAGGGACAACGCTGTCC
  CCGCAGCAGCGCCTCCTCCCGGCGCCCGAGAGACCGGCACGCCACGGCCCCTCCCCCAAG
  GAACAGAGCAAAGGATGGTGGCCGCAGGCCCCACGCGAGCCCACAGGACACCGGCCCCTA
  GATTCCAGCCACCAAGCGGAAGCATGAGACCCGCCCACACTAGCCTCTGTGTTCCCGTTA
  GGGACATCACACCCTGTCTCACGTCGCAGTGCCATGGACGCAGCAGTTACAGCACCATTG
  TTTTAGCAGTGCGTGTTCATATATGGGCTTGCTACTTCCTGTAATGAGGACGTTCAACAT
  GGTGAGGGGCTACAAGAAAACGCTTTTCTGTACAGAGTCTTACTGTAGCTACGCTAATGG
  TTAACCTGATAGAATTAACTCGTATTTTTCTATGGTTTTAACCTGATGCTCCACTGTCTC
  CGTCATGGGGTTGTTTTGCTGTTTGGGGTTGGGCCTTGTTTCCCTTTCCTTTCTCCAGTC
  CACGTGTAGACTTTGCGCTTGATGAAGAAGCAGATCGGAAGTAACTGCTCCCTCCTCAAG
  GTTGTCTTCAGACGTCTTGGAGACGTTCCTAAACACTGAGGGGGAAGACAGCCAATAGCA
  CCCATTAAAAGAAATACCTAAATAAAACCTCTCTCCCACTCAGCTATGCTAGGGCTTGGC
  TGTAGGTGTGCACTGTCTATTTACATCCGTCCTTACAACCATCCTTGTCCTCCTTGGTAC
  CGTATCAAGCTCTTTCCCATGACATTTGGTTAAAAAAAAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001039350
• Insert Size: 3800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001039350.1.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001039350.1, NP_001034439.1
• RefSeq Size: 4571 bp
• RefSeq ORF: 2406 bp
• Locus ID: 1804
• Cytogenetics: 7q36.2
• Protein Families: Druggable Genome, Protease, Transmembrane
• Gene Summary: This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
  Transcript Variant: This variant (3) contains an alternate 5'-most exon and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a shorter and distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.