GABA A Receptor gamma 2 (GABRG2) (NM_198904) Human Untagged Clone

CAT#: SC307809

GABRG2 (untagged)-Human gamma-aminobutyric acid (GABA) A receptor, gamma 2 (GABRG2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GABA A Receptor gamma 2
• Synonyms: CAE2; DEE74; ECA2; EIEE74; FEB8; GEFSP3
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_198904 edited
  TCTGCCCCCTGAATATTAATTCCCTAATCTGGTAGCAATCCATCTCCCCAGTGAAGGACC
  TACTAGAGGCAGGTGGGGGGAGCCACCATCAGATCATAAGCATAAGAATAATACAAAGGG
  GAGGGATTCTTCTGCAACCAAGAGGCAAGAGGCGAGAGAAGGAAAAAAAAAAAAGCGATG
  AGTTCGCCAAATATATGGAGCACAGGAAGCTCAGTCTACTCGACTCCTGTATTTTCACAG
  AAAATGACGGTGTGGATTCTGCTCCTGCTGTCGCTCTACCCTGGCTTCACTAGCCAGAAA
  TCTGATGATGACTATGAAGATTATGCTTCTAACAAAACATGGGTCTTGACTCCAAAAGTT
  CCTGAGGGTGATGTCACTGTCATCTTAAACAACCTGCTGGAAGGATATGACAATAAACTT
  CGGCCTGATATAGGAGTGAAGCCAACGTTAATTCACACAGACATGTATGTGAATAGCATT
  GGTCCAGTGAACGCTATCAATATGGAATACACTATTGATATATTTTTTGCGCAAACGTGG
  TATGACAGACGTTTGAAATTTAACAGCACCATTAAAGTCCTCCGATTGAACAGCAACATG
  GTGGGGAAAATCTGGATTCCAGACACTTTCTTCAGAAATTCCAAAAAAGCTGATGCACAC
  TGGATCACCACCCCCAACAGGATGCTGAGAATTTGGAATGATGGTCGAGTGCTCTACACC
  CTAAGGTTGACAATTGATGCTGAGTGCCAATTACAATTGCACAACTTTCCAATGGATGAA
  CACTCCTGCCCCTTGGAGTTCTCAAGTTATGGCTATCCACGTGAAGAAATTGTTTATCAA
  TGGAAGCGAAGTTCTGTTGAAGTGGGCGACACAAGATCCTGGAGGCTTTATCAATTCTCA
  TTTGTTGGTCTAAGAAATACCACCGAAGTAGTGAAGACAACTTCCGGAGATTATGTGGTC
  ATGTCTGTCTACTTTGATCTGAGCAGAAGAATGGGATACTTTACCATCCAGACCTATATC
  CCCTGCACACTCATTGTCGTCCTATCCTGGGTGTCTTTCTGGATCAATAAGGATGCTGTT
  CCAGCCAGAACATCTTTAGGTATCACCACTGTCCTGACAATGACCACCCTCAGCACCATT
  GCCCGGAAATCGCTCCCCAAGGTCTCCTATGTCACAGCGATGGATCTCTTTGTATCTGTT
  TGTTTCATCTTTGTCTTCTCTGCTCTGGTGGAGTATGGCACCTTGCGTTATTTTGTCAGC
  AACCGGAAACCAAGCAAGGACAAAGATAAAAAGAAGAAAAACCCTCTTCTTCGGATGTTT
  TCCTTCAAGGCCCCTACCATTGATATCCGCCCAAGATCAGCAACCATTCAAATGAATAAT
  GCTACACACCTTCAAGAGAGAGATGAAGAGTACGGCTATGAGTGTCTGGACGGCAAGGAC
  TGTGCCAGTTTTTTCTGCTGTTTTGAAGATTGTCGAACAGGAGCTTGGAGACATGGGAGG
  ATACATATCCGCATTGCCAAAATGGACTCCTATGCTCGGATCTTCTTCCCCACTGCCTTC
  TGCCTGTTTAATCTGGTCTATTGGGTCTCCTACCTCTACCTGTGAGGAGGTATGGGTTTT
  ACTGATATGGTTCTTATTCACTGAGTCTCATGGAGAGATGTCTGTTCTAAGTCCACTTAA
  ATAATCCTCTATGTGGTTGATAATGATCTGAATCTGTTTCTATGTCCAAACCTGGTAAAT
  TTTATAATGTCATATTGTTTGTGCCAAGCCCTCCTTTGGTTAGTGTACTTTGAACTTCGA
  TGTTTGCTGTGTTTCAAACCTGCAAGGCAAAGTAAAATTAGAGCAAGAACATTCAAACCA
  AATAAGATATTTTTCAGCTACAGCAAATAAAACAGTGAAAGCCCTGACTATTTACAGTAG
  TGGTATCCTTACTAGATTCATAATGCAATTAGATAGAAAAGGTCCAAAACTGTACCCTAT
  GTTCACTCCGGGTCAAGTTGTGATAAATTTGATCCCAATAGAATACCTCCCTCATTTAAG
  AAAAATCATAACTCACTTTAAATATGAAAGCCTAGTCCAGAAATCTATTACACCTTTATC
  TCAAGATAGGAAGAAAATTTCCTCCACATTCATGTACAATGATGTAAATATTTCAATAAC
  TTAGAATGCTTCAAGTTTAGTGCATGCATCTCTTTAGATCCAAAATAAATGGACTGAAGT
  TATCATCCTATTGTCTTTTATTTTGTGTCCTTGGGCTATAAAAGATTCCTGAATGTAATT
  ATAAGGATTTGGGTTTGGAAATGGAGGGAGGAATTTTCATTGCCTTCTCCCTCATGCATG
  AAGATTCGAACAGCTTATTTTTTCCTTGTATGACATATTACAACACTTTAAGTAAAATAT
  AGACTGGATAATCAACATTTGCCACCTCTAAATATGCCCAATTTCATAACTAGAGTATAA
  AGTAATCGTATGTGCTTGCCGCTATTTTTTTCTTCCTTTTAGGATGATAGATCATAACAG
  AACTTATTCTCCATCTCAAGATCTGCTTCTAGTGATTGTGAGTGCCTTGTGGGCAGAATC
  CTTGTCATTTCCTCTTTGGGTCTGTAGCACCTTGCATAGTGCCTGGCATATAGTTGGTGC
  TCAATAAATATGGTTTGAAGTGAATTGCCCTCACATGCTTCTGGCAAATCTCTGTGCTGG
  CCTGAAACCAGTGACTCATCTTCTCACATAGGTGTTGTCAAGTGATATTTGATTTTGTAA
  AAATAACCAGTAGGATCCAAAGAACTTTAGCTATTTATGTTCATCTTCAAAAAATTATTT
  TAGGCAAAGTCCATACTCCTTTTAAAACAATATTTATGTCCTATGTTTGTGTATAGACAT
  GACTCTACTAGGGCATAATTAGAGTTTGTGTATTATTTTTCCAGGTTTGGGGATGAGTCA
  GTCCTTGCCCATCCACAATTTTGTTTGTGAACTTATAACAGGAATAAGCAAAATTCATAC
  CTGACTAGTGTTCAGAATGTAGCATTCTGTGCGAAAAAGTATTGAAGATTAGCTTTTAAA
  AACTGAAAAAAAAAAATGAATGACTCACATAGAGGTTGAGCCAATGACTGTGGCCTCATT
  AGATTACATTGTAGTTAAACAAAGCAATTTCTCCAGACTTAAAACATGATGAGTTGAGCT
  CTATCTTCATGTACTCATCCTGAATCCTTATTTTTCTAAAATAGCACCCTTTGTTAATTA
  TTTTTATGGAAATTATTACTCTGTCATAATTAAATCATAGCTAGTATAACTTTACAGATA
  ACCTAAAAAGAATAGAAAAGAAGAGAGAGTGGCTTTGTCAGTATAAAACCATGTAAAGTC
  ATCATCAAGTCATCTGGATGAATCTTGAAACACATTTAGCTGCCAGTTTTACAAACCTTT
  AATATATCAGTGCTCCAGTATATAACCTCAAACAAATGTAAATAGAACGAATTATTTTCT
  TGTTTTGAATTGTCAATATATTAAATGTTGACTCTTTGGGAGAGTTGTTGGCAAGTTTCA
  ATGGTGAGAAACATTATTGTCAACTTGAAATGTGTTCTGTAATGGGGACACTACAAAAAG
  CTAGCTTTCCAATGTGTGCATAGTATTGGCAATATGAATATATATTATATATAATCTAAT
  ACTTATTATAAGCTGCTCCCTGTCTATGTATTTGGAAACCTTTTCACAAAGGGAATTGCC
  TAACATGTGGACTTTTACAATAAAAATGCTGCATTCTAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_198904
• Insert Size: 3800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_198904.1.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_198904.1, NP_944494.1
• RefSeq Size: 3871 bp
• RefSeq ORF: 1428 bp
• Locus ID: 2566
• UniProt ID: P18507
• Cytogenetics: 5q34
• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) lacks an alternate in-frame exon, compared to variant 3. It encodes isoform 1 which is shorter than isoform 3.