KCNE2 (NM_172201) Human Untagged Clone

CAT#: SC306737

KCNE2 (untagged)-Human potassium voltage-gated channel, Isk-related family, member 2 (KCNE2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNE2
• Synonyms: ATFB4; LQT5; LQT6; MIRP1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_172201 edited
  GCAGGAGGGAAGCATGTCTACTTTATCCAATTTCACACAGACGCTGGAAGACGTCTTCCG
  AAGGATTTTTATTACTTATATGGACAATTGGCGCCAGAACACAACAGCTGAGCAAGAGGC
  CCTCCAAGCCAAAGTTGATGCTGAGAACTTCTACTATGTCATCCTGTACCTCATGGTGAT
  GATTGGAATGTTCTCTTTCATCATCGTGGCCATCCTGGTGAGCACTGTGAAATCCAAGAG
  ACGGGAACACTCCAATGACCCCTACCACCAGTACATTGTAGAGGACTGGCAGGAAAAGTA
  CAAGAGCCAAATCTTGAATCTAGAAGAATCGAAGGCCACCATCCATGAGAACATTGGTGC
  GGCTGGGTTCAAAATGTCCCCCTGATAAGGGAGAAAGGCACCAAGC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_172201 unedited
  GGTCAAATTTGTAAACGACTCACTATAGGGCGGCCGCGAATCGCCCTTGCAGGAGGGAAG
  CATGTCTACTTTATCCAATTTCACACAGACGCTGGAAGACGTCTTCCGAAGGATTTTTAT
  TACTTATATGGACAATTGGCGCCAGAACACAACAGCTGAGCAAGAGGCCCTCCAAGCCAA
  AGTTGATGCTGAGAACTTCTACTATGTCATCCTGTACCTCATGGTGATGATTGGAATGTT
  CTCTTTCATCATCGTGGCCATCCTGGTGAGCACTGTGAAATCCAAGAGACGGGAACACTC
  CAATGACCCCTACCACCAGTACATTGTAGAGGACTGGCAGGAAAAGTACAAGAGCCAAAT
  CTTGAATCTAGAAGAATCGAAGGCCACCATCCATGAGAACATTGGTGCGGCTGGGTTCAA
  AATGTCCCCCTGATAAGGGAGAAAGGCACCAAGCAAGGGCGAATTCGCCCTTGCAGGAGG
  GAAGCATGTCTACTTTATCCAATTTCACACAGACGCTGGAAGACGTCTTCCGAAGGATTT
  TTATTACTTATATGGACAATTGGCGCCAGAACACAACAGCTGAGCAAGAGGCCCTCCAAG
  CCAAAGTTGATGCTGAGAACTTCTACTATGTCATCCTGTACCTCATGGTGATGATTGGGA
  TGTTCTCTTTCATCATCGTGGCCATCCTGGTGAGCACTGTGAAAATCCAGAGACGGGGAA
  CACTCCATGACCCCTACACCAGTACATTGTAGAGGACTGGCAGAAAAGTACAAGACCAAA
  TCTTGATCTAGAAGATCGAAGGCCACATCCATGGAGACATTGTGCGGCTGGGGTCAAATG
  TCCCCCTGGTAAGGAGAAAGCACCAACCAGGGCGATTCGATCTGTACCGATTT
  
  3' Read Nucleotide Sequence

  >Forward primer walk for NM_172201 unedited
  GGTCAAATTTGTAAACGACTCACTATAGGGCGGCCGCGAATCGCCCTTGCAGGAGGGAAG
  CATGTCTACTTTATCCAATTTCACACAGACGCTGGAAGACGTCTTCCGAAGGATTTTTAT
  TACTTATATGGACAATTGGCGCCAGAACACAACAGCTGAGCAAGAGGCCCTCCAAGCCAA
  AGTTGATGCTGAGAACTTCTACTATGTCATCCTGTACCTCATGGTGATGATTGGAATGTT
  CTCTTTCATCATCGTGGCCATCCTGGTGAGCACTGTGAAATCCAAGAGACGGGAACACTC
  CAATGACCCCTACCACCAGTACATTGTAGAGGACTGGCAGGAAAAGTACAAGAGCCAAAT
  CTTGAATCTAGAAGAATCGAAGGCCACCATCCATGAGAACATTGGTGCGGCTGGGTTCAA
  AATGTCCCCCTGATAAGGGAGAAAGGCACCAAGCAAGGGCGAATTCGCCCTTGCAGGAGG
  GAAGCATGTCTACTTTATCCAATTTCACACAGACGCTGGAAGACGTCTTCCGAAGGATTT
  TTATTACTTATATGGACAATTGGCGCCAGAACACAACAGCTGAGCAAGAGGCCCTCCAAG
  CCAAAGTTGATGCTGAGAACTTCTACTATGTCATCCTGTACCTCATGGTGATGATTGGGA
  TGTTCTCTTTCATCATCGTGGCCATCCTGGTGAGCACTGTGAAAATCCAGAGACGGGGAA
  CACTCCATGACCCCTACACCAGTACATTGTAGAGGACTGGCAGAAAAGTACAAGACCAAA
  TCTTGATCTAGAAGATCGAAGGCCACATCCATGGAGACATTGTGCGGCTGGGGTCAAATG
  TCCCCCTGGTAAGGAGAAAGCACCAACCAGGGCGATTCGATCTGTACCGATTT
  
• Restriction Sites: Please inquire
• ACCN: NM_172201
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_172201.1, NP_751951.1
• RefSeq Size: 809 bp
• RefSeq ORF: 372 bp
• Locus ID: 9992
• UniProt ID: Q9Y6J6
• Cytogenetics: 21q22.11
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul 2008]