TRIF (TICAM1) (NM_182919) Human Untagged Clone

CAT#: SC120956

TICAM1 (untagged)-Human toll-like receptor adaptor molecule 1 (TICAM1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRIF
• Synonyms: IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_182919 edited
  GTGTGGAACATGCCTTCACCACCTCCAGCTTCTGCTGCCGGAGGCTGCACCCACCTGTGC
  CCATGGCCTGCACGGGCCCATCACTTCCTAGCGCCTTCGACATTCTAGGTGCAGCAGGCC
  AGGACAAGCTCTTGTATCTGAAGCACAAACTGAAGACCCCACGCCCAGGCTGCCAGGGGC
  AGGACCTCCTGCATGCCATGGTTCTCCTGAAGCTGGGCCAGGAAACTGAGGCCAGGATCT
  CTCTAGAGGCATTGAAGGCCGATGCGGTGGCCCGGCTGGTGGCCCGCCAGTGGGCTGGCG
  TGGACAGCACCGAGGACCCAGAGGAGCCCCCAGATGTGTCCTGGGCTGTGGCCCGCTTGT
  ACCACCTGCTGGCTGAGGAGAAGCTGTGCCCCGCCTCGCTGCGGGACGTGGCCTACCAGG
  AAGCCGTCCGCACCCTCAGCTCCAGGGACGACCACCGGCTGGGGGAACTTCAGGATGAGG
  CCCGAAACCGGTGTGGGTGGGACATTGCTGGGGATCCAGGGAGCATCCGGACGCTCCAGT
  CCAATCTGGGCTGCCTCCCACCATCCTCGGCTTTGCCCTTTGGGACCAGGAGCCTCCCAC
  GCCCCATTGACGGTGTTTCGGACTGGAGCCAAGGGTGCTCCCTGCGATCCACTGGCAGCC
  CTGCCTCCCTGGCCAGCAACTTGGAAATCAGCCAGTCCCCTACCATGCCCTTCCTCAGCC
  TGCACCGCAGCCCACATGGGCCCAGCAAGCTCTGTGACGACCCCCAGGCCAGCTTGGTGC
  CCGAGCCTGTCCCCGGTGGCTGCCAGGAGCCTGAGGAGATGAGCTGGCCGCCATCGGGGG
  AGATTGCCAGCCCACCAGAGCTGCCAAGCAGCCCACCTCCTGGGCTTCCCGAAGTGGCCC
  CAGATGCAACCTCCACTGGCCTCCCTGATACCCCCGCAGCTCCAGAAACCAGCACCAACT
  ACCCAGTGGAGTGCACCGAGGGGTCTGCAGGCCCCCAGTCTCTCCCCTTGCCTATTCTGG
  AGCCGGTCAAAAACCCCTGCTCTGTCAAAGACCAGACGCCACTCCAACTTTCTGTAGAAG
  ATACCACCTCTCCAAATACCAAGCCGTGCCCACCTACTCCCACCACCCCAGAAACATCCC
  CTCCTCCTCCTCCTCCTCCTCCTTCATCTACTCCTTGTTCAGCTCACCTGACCCCCTCCT
  CCCTGTTCCCTTCCTCCCTGGAATCATCATCGGAACAGAAATTCTATAACTTTGTGATCC
  TCCACGCCAGGGCAGACGAACACATCGCCCTGCGGGTTCGGGAGAAGCTGGAGGCCCTTG
  GCGTGCCCGACGGGGCCACCTTCTGCGAGGATTTCCAGGTGCCGGGGCGCGGGGAGCTGA
  GCTGCCTGCAGGACGCCATAGACCACTCAGCTTTCATCATCCTACTTCTCACCTCCAACT
  TCGACTGTCGCCTGAGCCTGCACCAGGTGAACCAAGCCATGATGAGCAACCTCACGCGAC
  AGGGGTCGCCAGACTGTGTCATCCCCTTCCTGCCCCTGGAGAGCTCCCCGGCCCAGCTCA
  GCTCCGACACGGCCAGCCTGCTCTCCGGGCTGGTGCGGCTGGACGAACACTCCCAGATCT
  TCGCCAGGAAGGTGGCCAACACCTTCAAGCCCCACAGGCTTCAGGCCCGAAAGGCCATGT
  GGAGGAAGGAACAGGACACCCGAGCCCTGCGGGAACAGAGCCAACACCTGGATGGTGAGC
  GGATGCAGGCGGCGGCACTGAACGCAGCCTACTCAGCCTACCTCCAGAGCTACTTGTCCT
  ACCAGGCACAGATGGAGCAGCTCCAGGTGGCTTTTGGGAGCCACATGTCATTTGGGACTG
  GGGCGCCCTATGGGGCTCGAATGCCCTTTGGGGGCCAGGTGCCCCTGGGAGCCCCGCCAC
  CCTTTCCCACTTGGCCGGGGTGCCCGCAGCCGCCACCCCTGCACGCATGGCAGGCTGGCA
  CCCCCCCACCGCCCTCCCCACAGCCAGCAGCCTTTCCACAGTCACTGCCCTTCCCGCAGT
  CCCCAGCCTTCCCTACGGCCTCACCCGCACCCCCTCAGAGCCCAGGGCTGCAACCCCTCA
  TTATCCACCACGCACAGATGGTACAGCTGGGGCTGAACAACCACATGTGGAACCAGAGAG
  GGTCCCAGGCGCCCGAGGACAAGACGCAGGAGGCAGAATGACCGCGTGTCCTTGCCTGAC
  CACCTGGGGAACACCCCTGGACCCAGGCATCGGCCAGGACCCCATAGAGCACCCCGGTCT
  GCCCTGTGCCCGGTGGACAGT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_182919 unedited
  NCGCCATCCCCCGCCCCCCGCCGCATTGGGCGGTAGGCGTGTACGGTGGGAGGTCTATAT
  AAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGC
  CGCGAATTCGGCACGAGGGCGGGGTGGAGCCAGCGCCCTCAGCGCGCTACGGTCCGCGGG
  CAACTCCGCAGAAGCCCCAGCCCCCAGGACCCCAGGACCCAGTGGCGCAGCCGGCAGCCC
  CGGATCCCTGATCTGCTTGGGCAGCTCCTGCAGAACCTGGAACAGTGAATGGGTAGGGGA
  CACTGGGCGTGCAGAAGGCGGGGGGCAGTGTGGAACATGCCTTCACCACCTCCAGCTTCT
  GCTGCCGGAGGCTGCACCCACCTGTGCCCATGGCCTGCACGGGCCCATCACTTCCTAGCG
  CCTTCGACATTCTAGGTGCAGCAGGCCAGGACAAGCTCTTGTATCTGAAGCACAAACTGA
  AGACCCCACGCCCAGGCTGCCAGGGGCAGGACCTCCTGCATGCCATGGTTCTCCTGAAGC
  TGGGCCAGGAAACTGAGGCCAGGATCTCTCTAGAGGCATTGAAGGCCGATGCGGTGGCCC
  GGCTGGTGGCCCGCCAGTGGGCTGGCGTGGACAGCACCGAGGACCCAGAGGAGCCCCCAG
  ATGTGTCCTGGGCTGTGGCCCGCTTGTACCACCTGCTGGCTGAGGAGAAGCTGTGCCCCG
  CCTCGCTGCGGGACGTGGCCTACCAGGAAGCCGTCCGCACCCTCAGCTCCAGGGACGACC
  ACTCGCTGNGGGCACTTCANGATGANGCCCGAAACCTGTGTGGGGTGGACATTGCTGGNG
  ATCCAGGGAGCATCCGGACGCTCCAGTNCATCTGGGCTGCCTCCCACATCCTNCGCTTTG
  CCATTTGGN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_182919
• Insert Size: 3000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_182919.1, NP_891549.1
• RefSeq Size: 2460 bp
• RefSeq ORF: 2139 bp
• Locus ID: 148022
• UniProt ID: Q8IUC6
• Cytogenetics: 19p13.3
• Protein Families: Druggable Genome
• Protein Pathways: Toll-like receptor signaling pathway
• Gene Summary: This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. Mutations in this gene are associated with encephalopathy, acute, infection-induced. [provided by RefSeq, Jul 2020]