PICK1 (NM_012407) Human Untagged Clone

CAT#: SC115422

PICK1 (untagged)-Human protein interacting with PRKCA 1 (PICK1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PICK1
• Synonyms: PICK; PRKCABP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_012407 edited
  GTGGGTTCAGGTACCAGCCTGGCCGGGACCCGGCTGTGGGACCAACGCTTCCGGTGAGCG
  ACAGAGGCAGCTCCCCAGGGCCTGGAGACCCGTGGGGCGGACTCTGGGATCTGAGCCTAT
  CGCCCTGGCCTGGAGCCCCCCTTTGTACCTATTCCCCATTCCCCTACCGAGCTGGGCAGT
  TAGCCAGCCCACTCCAACTCTCGGAACCATGTTTGCAGACTTGGATTATGACATCGAAGA
  GGATAAACTCGGAATCCCGACTGTGCCTGGGAAGGTGACCCTGCAGAAGGATGCTCAGAA
  CCTGATCGGGATCAGCATTGGAGGAGGGGCCCAGTACTGTCCCTGCCTCTATATCGTCCA
  GGTATTTGACAACACCCCAGCAGCCTTGGACGGCACAGTGGCAGCTGGCGATGAGATCAC
  CGGTGTCAATGGCAGGTCAATCAAAGGGAAAACTAAGGTGGAGGTGGCGAAGATGATTCA
  GGAGGTGAAGGGGGAGGTGACCATCCACTACAACAAGCTGCAGGCGGACCCCAAGCAGGG
  CATGTCCCTGGACATTGTGTTGAAGAAAGTCAAGCACCGGCTGGTGGAGAACATGAGTTC
  AGGGACCGCAGATGCTCTGGGCCTGAGCCGGGCCATCCTGTGCAATGATGGGCTTGTCAA
  GAGGCTAGAGGAGCTGGAGCGGACCGCTGAGCTATACAAAGGGATGACGGAACACACCAA
  GAACCTCCTACGGGCCTTTTATGAGCTGTCGCAGACTCACCGGGCCTTTGGGGACGTGTT
  CTCCGTGATCGGGGTGCGGGAGCCCCAGCCAGCTGCGAGCGAGGCTTTTGTGAAGTTCGC
  CGATGCCCACCGCAGCATCGAGAAGTTCGGCATTCGGCTTCTGAAAACCATCAAGCCGAT
  GCTGACGGATCTGAACACGTACCTCAACAAAGCCATCCCGGACACTCGCCTCACCATCAA
  GAAGTACCTGGACGTGAAGTTTGAGTACCTGTCGTACTGCCTGAAGGTGAAGGAGATGGA
  TGACGAGGAATACAGCTGCATTGCCCTAGGCGAGCCCCTTTACCGGGTGAGCACCGGCAA
  CTATGAGTACCGCCTGATCCTGCGCTGCCGCCAGGAGGCGCGCGCCCGCTTCTCCCAGAT
  GCGCAAGGATGTGCTGGAGAAGATGGAGCTGCTGGACCAGAAGCACGTCCAGGACATCGT
  GTTCCAGCTGCAGCGCCTCGTGTCCACCATGTCCAAGTACTACAACGACTGCTACGCAGT
  GCTGCGGGATGCCGACGTCTTCCCCATCGAGGTAGACCTGGCGCACACCACATTGGCCTA
  TGGCCTCAACCAGGAGGAGTTCACAGATGGGGAGGAGGAGGAGGAGGAGGAAGACACGGC
  AGCTGGGGAGCCGTCCAGGGATACACGAGGGGCTGCTGGGCCCTTGGACAAGGGTGGAAG
  CTGGTGTGACTCCTGAGTGCCCCGCGGCTGTGGTGCCGGGGGCAGGGTGCGTGGGAGGAC
  GGAGCCTGGGAGCGGGGCGGGGCCGCCGCGCAAGGGGGCGACGCATAAAGGCCTGCTGGC
  TTGGGGCGCCTGCCTCCCTGCTCCTCTGTCCTCGCACAGCGAACCTGGGCTCCTGCCCAG
  GACAGGCACCAGGGTCATGGCCTGGGACCTGGACACTGGCCCCTCCACCCTCCCTCCCCT
  CCCGGCTCCCCGGCCAGAGGGAGAGCTTGGTCTCTGGACCTGCCTTAGGAAGGAGAGGGA
  GGGCAGGAAGGAAAAGAAAGGACTTGGAGGTGGCAGGAGTCCGAGCCCTGCTCCTTGTGG
  GCGCTCACACTGCCCCCGGAGCCTGCTGGGAGTGGGGCCAGCCGTGGACAGCTGAGGTTG
  GGGTCAATGCCTCCTGGGCACCCTTGCCTCGCCCCAGACCGGCCCGTCCAGTCCCCATCA
  CACCTCGGCGGCCTTTATTTATTCTGTTCCCCCAGCTCGGCCACTTCTCTGAAGGAGGGC
  TGGGTTCTGGGCCTGTATCGAATAAACACAAACCTGGATGGCGCAAAAAAAAAAAAAAAA
  AA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012407
• Insert Size: 2100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_012407.2.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012407.2, NP_036539.1
• RefSeq Size: 2083 bp
• RefSeq ORF: 1248 bp
• Locus ID: 9463
• UniProt ID: Q9NRD5
• Cytogenetics: 22q13.1
• Domains: PDZ
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.