FBXL8 (NM_018378) Human Untagged Clone

CAT#: SC113525

FBXL8 (untagged)-Human F-box and leucine-rich repeat protein 8 (FBXL8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXL8
• Synonyms: FBL8
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_018378, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCGAGCCTGGAGAGGGACTGCCAGAGGAGGTGCTGGCACTCATCTTCCGCCACCTGTCCCTGAGAG
  ACCGTGCTGCCGCCGCCAGGGTCTGCAGGGCCTGGGCCGCCGCTGCTACCTGCAGCGCCGTGTGGCACGA
  CACAAAAATCAGTTGCGAATGTGAGCTGGAAGGCATGCTGCCACCTTATCTGTCCGCCTGCCTCGACCAC
  ATTCACAACCTACGGCTGGAATTTGAGCCATCGAGGAAGCCGAGCCGCCGGGCGGCCATCGAGCTGCTGA
  TGGTTCTGGCGGGCCGTGCCCCGGGGCTGCGAGGCCTGCGCCTGGAGTGCCGCGGAGAAAAACCGCTCTT
  CGACGCGGGCCGCGACGTCCTGGAGGCTGTGCACGCTGTATGCGGGGCGGCCAGCCAGCTACGCCACCTC
  GACCTGCGGCGCTTGTCCTTCACACTGGACGACGCGCTGGTGCTGCAGGCGGCGCGCAGCTGTCCCGAGC
  TCCACAGCCTTTTTCTGGACAACAGTACCCTAGTGGGCAGCGTGGGTCCCGGCTCAGTGCTCGAGCTACT
  GGAGGCCTGCCCGCGCCTGCGCGCTCTCGGCCTGCACCTAGCCAGTTTGTCGCACGCCATCCTCGAAGCA
  CTGGCGGCGCCAGACCGAGCGCCTTTCGCGCTCTTGGCTCTGCGGTGCGCGTGCCCCGAAGATGCACGCG
  CGTCCCCGCTGCCCAACGAAGCCTGGGTCGCGTTGCGCCGCCGCCACCCTGGGCTGGCAGTGGAGCTGGA
  GCTGGAGCCCGCGCTGCCCGCTGAGAGCGTGACGCGCGTCCTGCAGCCAGCCGTCCCCGTGGCTGCGCTG
  CGCCTCAACCTCTCAGGCGACACCGTAGGCCCAGTGCGCTTCGCAGCACACCACTACGCCGCAACCCTGT
  GCGCGCTCGAGGTGCGCGCAGCCGCTTCGGCCGAGCTGAACGCCGCGCTGGAGGAGCTGGCGGCGCGCTG
  CGCGGCCCTGCGCGAGGTGCATTGTTTCTGCGTGGTGAGCCACTCGGTGCTGGACGCCTTCCGCGCGCAC
  TGCCCGCGCCTGCGCACCTATACCCTCAAGCTCACGCGCGAGCCGCATCCCTGGAGGCCTACGCTCGTGG
  CGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018378 unedited
  AAAAGTTCCGATTAGTATACGATTTACTATAGGGCGGCCGCGAATTCGCACCAGGTCCGC
  CCGCGCGTCCCGCCCCGCGGGCTCCCGGTGGCTGCTTCCCGTCCGCTGTCCTCTGCTGCC
  AGTCCCCTGCCCCGGGCAAAGCCCATCTGGTCCGCCGAGCAGGCCGGAGCTATTGGGAGT
  GGCGGATCCTCCCACCCCAGCCGGATCTGGGCCATGGCCGAGCCTGGAGAGGGACTGCCA
  GAGGAGGTGCTGGCACTCATCTTCCGCCACCTGTCCCTGAGAGACCGTGCTGCCGCCGCC
  AGGGTCTGCAGGGCCTGGGCCGCCGCTGCTACCTGCAGCGCCGTGTGGCACGACACAAAA
  ATCAGCCAGCCGTCCCCGTGGCTGCGCTGCGCCTCAACCTCTCAGGCGACACCGTAGGCC
  CAGTGCGCTTCGCAGCACACCACTACGCCGCAACCCTGTGCGCGCTCGAGGTGCGCGCAG
  CCGCTTCGGCCGAGCTGAACGCCGCGCTGGAGGAGCTGGCGGCGCGCTGCGCGGCCCTGC
  GCGAGGTGCATTGTTTCTGCGTGGTGAGCCACTCGGTGCTGGACGCCTTCCGCGCGCACT
  GCCCGCGCCTGCGCACCTATACCCTCAAGCTCACGCGCGAGCCGCATCCCTGGAGGCCTA
  CGCTCGTGGCGTGATTGGGCGACTTCTCTCCCCCGTCCCGTGGACACGCCCCACCCGCTC
  GGTCCTGGACACACTGCCCCCCTCTCTTGCCTCCACCCCTCTGCGGACTCTGCAGCTCCG
  CGGCCCCGGCCCAGGNAGAGGGAAGGCACGGGCCCCGGCCCGGGCCTCAAGGGTGAGTGT
  GAAATAAAACAATCCTGCAGTGAAAAAAAAAANNTNCAACNNNC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_018378 unedited
  TTTATTAACCTTTTTTTTTTTTTTTTTCACTGTTGGATTTGTTTATTTCACACTCACCCT
  TGAGGCCCGGCCCGCGCCCGTGCCCTCCCTCTCCCTGCGCCGGGGCCGCGGAGCTGCAGA
  GTCCGCAGAGGGGTGGAGGCAAGAGAGGGGGGCAGTGTGTCCAGGACCGAGCGGGTGGGG
  CGTGTCCACGGGGACGGGGGAGAGAAGTCGCCCAATCACGCCACGAGCGTAGGCCTCCAG
  GGATGCGGCTCGCGCGTGAGCTTGAGGGTATAGGTGCGCAGGCGCGGGCAGTGCGCGCGG
  AAGGCGTCCAGCACCGAGTGGCTCACCACGCAGAAACAATGCACCTCGCGCAGGGCCGCG
  CAGCGCGCCGCCAGCTCCTCCAGCGCGGCGTTCAGCTCGGCCGAAGCGGCTGCGCGCACC
  TCGAGCGCGCACAGGGTTGCGGCGTATTGGTGTGCTGCGAAGCGCACTGGGCCTACGGTG
  TCGCCTGAGAGGTTGAGGCGCATCGCATCCACGGGGACGGCTGGCTGATTTTTGTGTCGT
  GCCACACGGCGCTGCAGGTAGCAGCGGCGGCCCAGGCCCTGCAGACCCTGGCGGCGGCAG
  CACGGTCTCTCAGGGACAGGTGGCGGAAGATGAGTGCCAGCACCTCCTCTGGCAGTCCCT
  CTCCAGGCTCGGCCATGGCCCATATCCGGCTGGGGTGGGAGGATCCGNCACTCCCAATAG
  CTCCGGCCTGCTTCGCGGACCANATGGGCTTTTGCCCGGGGCAGGGGACTGGCACCAGAG
  NACAGCGGACGGGAAGCAGCCCCGGGAGCCCGCGGGGGCGGGACGCGCGGGCGGGACCTG
  GTGCCGGATTTCGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_018378
• Insert Size: 1000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_018378.2, NP_060848.2
• RefSeq Size: 1618 bp
• RefSeq ORF: 1125 bp
• Locus ID: 55336
• UniProt ID: Q96CD0
• Cytogenetics: 16q22.1
• Domains: F-box
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq, Jul 2008]