MXI1 (NM_130439) Human Untagged Clone

CAT#: SC109464

MXI1 (untagged)-Human MAX interactor 1 (MXI1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MXI1
• Synonyms: bHLHc11; MAD2; MXD2; MXI
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_130439, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGCAAACGCGGGCGGCCGCGCAAGGAGGCGCGCTGCGAGGGCGCGGGGCTGGCCCCCGCCGCGCCCC
  CGGCTGTGCCCCCCGCCGTGGCCGCGCCCCAGCCCCCGGCCCTGCCCGAGGACCCCGCTGGGGCCAAGCC
  CAGGTGCCCCTTCTCAGACATTTTCAACACCAGCGAGAACTCGATGGAGAAGCACATCAACACTTTTCTG
  CAGAACGTGCAGATTCTGCTCGAGGCCGCCAGCTACCTGGAGCAGATCGAGAAAGAAAACAAAAAGTGTG
  AACATGGCTACGCCTCTTCATTCCCGTCCATGCCGAGCCCCCGACTGCAGCATTCAAAGCCCCCACGGAG
  GTTGAGCCGGGCACAGAAACACAGCAGCGGGAGCAGCAACACCAGCACTGCCAACAGATCTACACACAAT
  GAGCTGGAAAAGAATCGACGAGCTCATCTGCGCCTTTGTTTAGAACGCTTAAAAGTTCTGATTCCACTAG
  GACCAGACTGCACCCGGCACACAACACTTGGTTTGCTCAACAAAGCCAAAGCACACATCAAGAAACTTGA
  AGAAGCTGAAAGAAAAAGCCAGCACCAGCTCGAGAATTTGGAACGAGAACAGAGATTTTTAAAGTGGCGA
  CTGGAACAGCTGCAGGGTCCTCAGGAGATGGAACGAATACGAATGGACAGCATTGGATCAACTATTTCTT
  CAGATCGTTCTGATTCAGAGCGAGAGGAGATTGAAGTGGATGTTGAAAGCACAGAGTTCTCCCATGGAGA
  AGTGGACAATATAAGTACCACCAGCATCAGTGACATTGATGACCACAGCAGCCTGCCGAGTATTGGGAGT
  GACGAGGGTTACTCCAGTGCCAGTGTCAAACTTTCATTCACTTCATAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_130439 unedited
  GCATTTTGTAATACGACTCACTATAGGGCGGCNCGCGATTCGGCACGAGGCGCGGCTGGG
  GCGGCAGGGGCGGCGGAGAGCGCGCCGAGCCGCGGCCGAGCTGGCCCGCCCGCCCGTCGC
  ACATGTTCCGGAACGGCGCCCGGCCGTAGCCGCCTGCGGCGCCTCCTGTCGGCCCGAGAA
  GGGAGTGCGGAGAGGCGCCGGTCGCCACCCGCGGTGCCCATGGAGCGGGTGAAGATGATC
  AACGTGCAGCGTCTGCTGGAGGCTGCCGAGTTTTTGGAGCGCCGGGAGCGAGAGTGTGAA
  CATGGCTACGCCTCTTCATTCCCGTCCATGCCGAGCCCCCGACTGCAGCATTCAAAGCCC
  CCACGGAGGTTGAGCCGGGCACAGAAACACAGCAGCGGGAGCAGCAACACCAGCACTGCC
  AACAGACGAGCTCATCTGCGCCTTTGTTTAGAACGCTTAAAAGTTCTGATTCCACTAGGA
  CCAGACTGCACCCGGCACATCAACACTTGGTTTGCTCAACAAAGCCAAAGCACACATCAA
  GAAACTTGAAGAAGCTGAAAGAAAAAGCCAGCACCAGCTCGAGAATTTGGAACGAGAACA
  GAGATTTTTAAAGTGGCGACTGGAACAGCTGCAGGGTCCTCAGGAGATGGAACGAATACG
  AATGGACAGCATTGGATCAACTATTTCTTCAGATCGTTCTGATTCAGAGCGAGAGGAGAT
  TGAAGTGGATGTTGAAAGCACAGAGTTCTTCCATGGNAGAAGTGGACANNTATAGTACCA
  CCAGCATCAGTGACATTGATGACCACAGCAGCCTGCCGAGTATTGGGAGTGACGAGGGTT
  ACTNCAGTGCCAGTGTCAAACTTTCATCACTTCATAGAACCCACATGACATANCAGTGCA
  GGGNCAAATATCACTGGGCCANNNTCATACAACATCTCTTAAATNGGNTCATGATGCAGN
  NCTCTCTTTAAAACAACANNACANACTATACTTGACAAAGGTCANAGGACCTGNATTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_130439 unedited
  NNNNGGGTCCACTATGGAACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTT
  TAAGTAATTAAGGGTAGTTAAATTATTTAAAGTATACAAAGTCCAAACAGCCAGGGGTAA
  GGTCTCCAAGAGGCCTTCCCAGGGTAAGGGAGAGGGCCACAGGGGAACCTTGGAGTTTGA
  AAGACAAAGGGAACACATGACATCAAAGTGCAGGCTAGAAATTTCACTTAGAAGAAAATA
  ACATTACTGAAAATATTCGTAAGAGTAACAATAGCACCTGCACAGTGGGACTGTGAGGAA
  GAGAGAGACTGCCTGTAGGAAAATGGAAGCAAATCTTTACATTAAAATGAGACAAGTGCT
  GAACTTAACTATGTTAACTATGATAGTGTGTCTACTATAGATATCAGATGGTTAAAAGCT
  GGTAAAAGGTAATGATTCTAAAAACAAAAATAGCATTGACCCTTTTTCTACCTAGCCCAG
  ACCTCATTCATTTTGTGCACTATAAAGAGTGAGGTGTGAGGTGTTTTATCATTATCAAAT
  GCTGCATCAAAATAGATGATTTTTTTCCCCATGTGTTTTTCCACTATAAAAGACATCTAT
  TTTTTTTTATGGATAAGCTTTAAAAAGATGTCATTTTGGTTTTCAACACATATAAACAGT
  TATCAAAATCTGAAATAAAAATGCTGCTGTGGCTCAGACCTTGGCCTGCTAATCTGCGTG
  CACAACTCTTCTGACCCACGCAGACAAAGAGGCACATGGAGCTTTTTCCTTTTGGCCCCC
  CCAATCCATACTCATAGGCCTTGTNAGATAGAGGCTGTCATGCATGGACTGCNTCCCATG
  TGCCTAANGGCANNCAGATGGANAAGTGGCANNCTGGTGCCTAGTGCTAACA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_130439
• Insert Size: 2400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_130439.1, NP_569157.1
• RefSeq Size: 3470 bp
• RefSeq ORF: 549 bp
• Locus ID: 4601
• UniProt ID: P50539
• Cytogenetics: 10q25.2
• Domains: HLH
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2), also referred to as SRalpha, differs in the 5' UTR and coding region, compared to variant 1. The resulting protein (isoform b) is longer and has a distinct N-terminus, compared to isoform a.