TTC5 (NM_138376) Human Untagged Clone

CAT#: SC100501

TTC5 (untagged)-Human tetratricopeptide repeat domain 5 (TTC5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TTC5
• Synonyms: Strap
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC100501 sequence for NM_138376 edited (data generated by NextGen Sequencing)
  ATGATGGCTGATGAAGAGGAAGAAGTCAAGCCGATCTTGCAGAAATTGCAGGAACTCGTG
  GATCAGCTCTACTCATTTCGAGACTGCTATTTCGAGACACATAGTGTTGAGGATGCTGGG
  AGGAAGCAACAGGATGTGCAGAAGGAGATGGAGAAAACCCTACAGCAGATGGAAGAAGTA
  GTGGGTTCTGTCCAGGGCAAGGCACAAGTTCTAATGCTAACTGGGAAAGCACTAAATGTG
  ACTCCTGACTATAGCCCTAAGGCTGAGGAGCTTCTGTCAAAGGCTGTGAAGCTGGAGCCC
  GAGCTGGTGGAAGCCTGGAACCAGCTGGGTGAGGTGTACTGGAAAAAAGGGGATGTTGCA
  GCTGCCCACACCTGCTTCTCAGGAGCCCTCACCCATTGCAGGAACAAAGTCTCCTTGCAA
  AACCTGTCAATGGTGCTTCGTCAGCTGCGGACTGACACTGAAGATGAACATTCTCACCAT
  GTCATGGACAGTGTCCGACAGGCTAAGTTGGCTGTTCAGATGGATGTCCATGATGGCCGC
  TCCTGGTATATTCTTGGGAATTCATATCTTTCCCTTTACTTCTCTACTGGCCAGAACCCT
  AAGATCTCCCAGCAAGCCCTCAGTGCCTATGCCCAAGCAGAGAAAGTTGACAGAAAAGCT
  TCTAGCAATCCTGACCTTCATCTGAACAGGGCGACGTTGCATAAATATGAAGAGAGTTAT
  GGGGAGGCCCTGGAGGGCTTCTCTCGGGCTGCAGCCCTGGACCCTGCCTGGCCAGAGCCC
  CGGCAACGAGAGCAACAACTTCTGGAATTCCTGGATAGATTAACCAGCCTCCTTGAGAGT
  AAGGGAAAGGTGAAGACCAAAAAGCTGCAGAGCATGCTGGGAAGCTTGCGCCCAGCCCAT
  CTAGGCCCTTGCAGTGATGGGCACTATCAGTCAGCCTCTGGGCAGAAAGTGACCCTGGAG
  CTCAAGCCACTGAGTACGCTTCAGCCTGGGGTGAACAGCGGTGCCGTCATCCTGGGAAAG
  GTGGTATTTAGCCTCACCACAGAGGAGAAAGTCCCCTTTACATTTGGCCTGGTAGATTCA
  GATGGACCTTGCTATGCAGTGATGGTGTACAATATAGTGCAGAGCTGGGGAGTGCTCATT
  GGAGACTCTGTAGCCATTCCTGAGCCCAACCTGCGGCTTCACCGAATTCAGCACAAAGGA
  AAGGACTATTCCTTTTCCAGTGTTCGAGTGGAGACGCCCCTCCTGCTAGTGGTGAATGGG
  AAGCCTCAGGGATCCAGCAGCCAGGCTGTTGCCACAGTGGCATCGCGACCACAGTGTGAA
  TGA
  
  Clone variation with respect to NM_138376.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_138376 unedited
  GTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGTGGCCGGGNAGAGATGGCTG
  ATGAAGAGGAAGAAGTCAAGCCGATCTTGCAGAAATTGCAGGAACTCGTGGATCAGCTCT
  ACTCATTTCGAGACTGCTATTTCGAGACACATAGTGTTGAGGATGCTGGGAGGAAGCAAC
  AGGATGTGCAGAAGGAGATGGAGAAAACCCTACAGCAGATGGAAGAAGTAGTGGGTTCTG
  TCCAGGGCAAGGCACAAGTTCTAATGCTAACTGGGAAAGCACTAAATGTGACTCCTGACT
  ATAGCCCTAAGGCTGAGGAGCTTCTGTCAAAGGCTGTGAAGCTGGAGCCCGAGCTGGTGG
  AAGCCTGGAACCAGCTGGGTGAGGTGTACTGGAAAAAAGGGGATGTTGCAGCTGCCCACA
  CCTGCTTCTCAGGAGCCCTCACCCATTGCAGGAACAAAGTCTCCTTGCAAAACCTGTCAA
  TGGTGCTTCGTCAGCTGCGGACTGACACTGAAGATGAACATTCTCACCATGTCATGGACA
  GTGTCCGACAGGCTAAGTTGGCTGTTAGATGGATGTCCATGATGGCCGCTCCTGGTATAT
  TCTTGGGAATTCATATCTTTCCCTTTACTTCTCTACTGGCCAGAACCCCTAAGATCTCCC
  AGCAAGCCCTCAGTGCCTATGCCCAAGCGAAAAAAGTTGACAGAAAAGCTTCTAGCAATC
  CTGACCTTTCATCTGAACAGGGCGACGTTGCATAAATATGAANAGAGTATTGGGGGAGGC
  CCTGGAGGGCTTCTTTTCGGCTTGAGCCCTGGACCCTGCCTGGCCAAAGCCCCGCAACAG
  AGCAACACTCTGGGATTCTGGAAGAAAAACACCTCTTTAAATAGGGGAAGGGGAGACCAA
  ACTTCNNACTGTGGGAAATTGGCCCACCCTTTAGCCTTGAGGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_138376 unedited
  NCACTTGNTACCGCGGCCGCTTTCTANGATCGAGTTTTTTTTTTTTTTTTTTCCAAAAAA
  TTTAATTCTGTTCCAGCCCCAAAGAAGAGGAAGGACCTAAAGTTCAAAAATAAAAATAAA
  AATTGCTAAAAATAAAAGCCATTACAAAATTAAGCCCCCTCCTTTAGCAATAAATACTGA
  ACTGATATATACATATGAGGCTTAGGAAGGAGGCAACAACAGGAACCTTGGGGACTCTGT
  CCCATGGCAAGATCCCAAGACTTCTACCAATTCCATGCTCTTTGCTTAAAACATAGAGAG
  CAGTGGAAGAGACAGGAGAGATATGCCAGAAGAGTATGTGGCCCTGTAGAGAGCTGGAAC
  ATGATGAGGACAGAGGAGAGAGAAGAGATACGAAGTGTAATACAGGCAGGGAAAGAGAAA
  GTCTTCATTTAAAACATTCCTCCCATCCCTGCTGAATCACTGGATGTGGCTGGACCGGCT
  GTCCAGAGCCTTGTCTCCTCTCCTCCACTCCCTGTTGAGCATGCAAGTCAAAGGTCATTC
  ACACTGTGGTCGCGATGCCACTGTGGCAACAGCCTGGCTGCTGGATCCCTGAGGCTTCCC
  ATTCACCACTAGCAGGAGGGGGCGTCTCACTCGAACACTGGAAAAGGAATAGTCTTTCCT
  TTGTGCTGAATTCGGTGAAGCCCGCAGGTTGGCTCANGAATGGCTACAGAGTCTCCAATG
  AGCAACTCCCCAGCTCTGCACTATATTGTACACCATCACTGCATAGCAGGTCCATCTGAA
  TCTACCAGGCCAAATGTTAAGGGGACTTTCCTCCTCTGGGGTGAGGGCTAATAACACCTT
  TCCCAGGATGACGGCCCCGCTGGTTACCCCCAGCTGGACCGTACTCCATGGCCTGGAGCT
  CAGGGTCACTTTCTGCCCAAAGCCTGACATGAAATGGCCCATACATGCAAGGGCCCTAAA
  TGGGCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_138376
• Insert Size: 1750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_138376.1, NP_612385.1
• RefSeq Size: 1845 bp
• RefSeq ORF: 1323 bp
• Locus ID: 91875
• UniProt ID: Q8N0Z6
• Cytogenetics: 14q11.2
• Domains: TPR
• Gene Summary: Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).[UniProtKB/Swiss-Prot Function]