GJA1(GJA1) (NM_000165) Human Tagged ORF Clone

CAT#: RC205303L3

Lenti ORF clone of Human gap junction protein, alpha 1, 43kDa (GJA1) , Myc-DDK-tagged

  • LentiORF®

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USD 763.00


Availability*
3 Weeks

Size
    • 10 ug

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Specifications

Product Data
Product Name GJA1(GJA1) (NM_000165) Human Tagged ORF Clone
Symbol GJA1
Synonyms AVSD3; CMDR; CX43; EKVP; GJAL; HLHS1; HSS; ODDD; PPKCA
Vector pLenti-C-Myc-DDK-P2A-Puro
Sequence Data
The ORF insert of this clone is exactly the same as(RC205303).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_000165
ORF Size 1146 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_000165.3, NP_000156
RefSeq Size 3130
RefSeq ORF 1149
Locus ID 2697
Cytogenetics 6q22.31
Domains CNX, Connexin43
Protein Families Ion Channels: Other, Transmembrane, Druggable Genome
Protein Pathways Gap junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC)
MW 42.8 kDa
Gene Summary This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.