Unc80 (NM_175510) Mouse Untagged Clone

CAT#: MC225476

Unc80 (untagged) - Mouse unc-80 homolog (C. elegans) (Unc80), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Unc80
• Synonyms: C030018G13Rik; C230061B10Rik; UNC-80
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC225476 representing NM_175510
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGAAGAGGAAGAGCTCCGAGGGCCAGGAGCAGGACGGCGGCCGCGGCATCCCTCTGCCCATCCAGA
  CCTTCCTGTGGCGGCAAACCAGTGCATTTTTGAGGCCTAAACTGGGGAAGCAATATGAAGCCTCTTGTGT
  GTCCTTTGAACGAGTGTTGGTGGAAAACAAGCTGCATGGCCTGTCCCCGGCCCTCTCTGAAGCAATCCAG
  AGCATTTCCAGATGGGAGCTAGTGCAGGCTGCCCTCCCTCATGTTCTCCACTGCACTGCAACTCTGCTAT
  CAAACAGGAACAAACTAGGCCATCAAGATAAGTTGGGTGTTGCTGAGACAAAACTCCTTCATACCCTGCA
  CTGGATGCTTCTTGAGGCCCCACAGGACTGCAACAATGATCAGTTTGGAGGTACAGACCGAGGTTCCAGC
  TGGGGTGGCAGCAGCAGTGCTTTCATCCACCAGATTGAAAACCAGGGTTCTCCCGGGCAGCCTTGCCGAA
  GCAGCTCCCATGATGAGGAAGAGAACAACCGAAGGAAGACCTTCCAGAACTCCATGGCTACCGTGGAGCT
  CTTTGTGTTTCTGTTTGCTCCTTTGGTGCACAGGATAAAGGAATCTGATCTCACCTTCCGACTGGCCAGT
  GGGTTGGTTATATGGCAGCCTATGTGGGAGCACAGACAGCCTGAGGTCTCCGGCTTTACTGCGCTGGTAA
  AGCCCATAAGGAACATCATTACAGCCAAAAGAAGCTCTCCAATCAACAGTCAGAGTCAGACCTGTGAATC
  ACCCAATCAAGACACCAGGCAGCAAGGAGAGGGACTTCAGGTGGTCAGTGAAGCACTGCAGTCGGATTCC
  ATCTCACCTAAGGCCACCATCTCAGGCTGCCATCAGGGAAACTCCTTCGATGGAAGCCTGTCCTCCCAAA
  CGTCCCAGGAAAGAGGCCCGTCACATTCCAGGGCCTCACTTGTGATACCACCATGCCAGAGGTCACGCTA
  TGCCACCTACTTCGATGTTGCCGTTCTCCGCTGCCTTCTCCAGCCCCACTGGTCTGAGGAAGGCACTCAG
  TGGTCTCTGATGTACTATCTACAAAGGCTGCGACACATGCTGGAAGAGAAACCAGAAAAGACCCCAGATC
  CAGATATTCCTCTGCTGCCCAGGCCCAGAAGTAGCTCGATGGTGGCAGCAGCTCCCTCACTGGTGAACAC
  CCACAAGACTCAAGATCTCACCATGAAGTGTAATGAAGAAGAAAAATCTCTGAGCCCTGAGGCTTTTTCC
  AAAGTCTCATTGACCAATCTCCGAAGATCTGCCGTCCCAGATCTATCTTCAGATCTGGGCATGAACATTT
  TTAAAAAGTTCAAAAGTCGCAAAGAAGACCGAGAGAGGAAGGGCTCCATTCCATTCCACCACACGGGGAA
  GAGGAGACCTAGACGAATGGGTGTACCATTCCTGCTGCATGAGGACCACCTAGACGTCTCACCTACCCGC
  AGCACATTCTCTTTTGGCAGTTTCTCTGGGCTTGGAGAAGATAGGAGAGGCATTGAAAAGGGAGGCTGGC
  AAACCACCATCTTAGGGAAGCTGACCCGGCGGGGCAGCTCAGATGCAGCCACTGAGATGGAAAGTCTGAG
  CGCCAGGCACTCGCACTCCCACCACACCCTGGTGAGCGACCTGCCAGACCACTCCAACAGCCACGGAGAG
  AACACTGTCAAGGAAGTGCGATCTCAGATCTCCACCATCACAGTTGCGACCTTCAACACTACGCTGGCAT
  CATTCAATGTAGGCTACGCGGACTTCTTCAGTGAACACATGAGGAAGCTCTGCAGCCAGGTGCCTATCCC
  AGAGATGCCACATGAGCCTCTGGCATGTGCCAACCTGCCACGAAGCCTCACAGACTCCTGCATAAACTAC
  AGCTACCTGGAGGACACAGAACATATTGATGGCACGAACAACTTTGTCCATAAGAACGGCATGCTGGATC
  TCTCTGTGGTTCTGAAGGCTGTTTATCTCGTTCTCAACCATGACATCAGCTCTCGCATCTGTGATGTGGC
  ACTTAACATTGTGGAATGTTTGCTTCAACTTGGGGTAGTTCCCTGTGTAGAAAAAAACAGGAAGAAAAGT
  GAAAACAAGGAAAATGAGTCTGTGGAAAAGAGACCAAGTGAGGGAGCCTTCCAGTTCAAAGGCGTGTCTT
  CAAGTTCCACCAGTGGGTTTGGGGCCCCTTCCGCTAGTGGAGCTGGAGATGGTGGAGGAGAAGAAGGAGG
  AGGTGGAGATGGAGGAGGAGGAGGTGGAGGAGGAGATGGAGGAGGAGGTGGAGGAGGTGGAGGTGGCCCT
  TATGAGAAGAATGAGAAGAACCAAGAGAAGGATGACAACATCCCTGTAAGCAACCATAGGCTTGCTCTTA
  CTATGCTCATCAAAATAGTCAAGTCACTGGGATGTGCCTATGGTTGCGGAGAAGGACATCGAGGGCTCTC
  TGGAGATCGCCTGAGACACCAGGTATTCCGAGAGAATGCCCAGAACTGCCTTACTAAGCTGTACAAGCTA
  GATAAAATACAGTTCCGACAAACCATGAGGGACTATGTGAACAAGGACTCTCTCAATAATGTAGTGGACT
  TCTTGCATGCTTTGCTAGGATTTTGTATGGAGCCGGTCACTGACAACAAAGCTGGGTTTGGAAATAACTT
  CACCACAGTGGACAACAAGTCCACAGCCCAAAATGTGGAAGGCATTATTGTCGGTGCCATGTTCAAGTCT
  CTCATCACACGCTGTGCCTCAACCACACATGAACTCCACAGCCCTGAGAATCTGGGACTGTACTGTGACA
  TCCGCCAGCTGGTTCAGTTTATCAAAGAAGCTCATGGGAATGTCTTCAGGAGAGTGGCTCTTAGTGCCCT
  GCTTGATAGTGCTGAAAAGTTAGCACCAGGGAAAAAGGTGGAAGAGAATGGACAGGAGTCTAAGCCTGTG
  GGCAGTAAAAGGTCAGAAGCAGGAAGCATTGCAGATAAAGGCCAGGTATCGTCAGCACCTGAGGAATGTC
  GAAGCTTCATGTCTGGTCGCCCCTCACAGACCCCAGAACATGATGAACCAATGCAAGGGGGCAACCTGGG
  ACGGAAAGATTTCTGGCGCAAGATGTTCAAATCCCAAAGCGCAGCAAGTGACACCAGCAGCCAGTCTGAG
  CAGGATACCTCGGAATGTACCACAGCCCACTCAGGGAACACCTCTGACCGGCGTGCCCGCTCACGATCCC
  GCAGAATCTCCCTGCGAAAGAAGTTGAAACTCCCCATAGGAAACTGGCTGAAGCGCTCCTCCCTCTCTGG
  CCTGGCAGATGGTGTAGAGGACCTCCTGGACATTAGCTCTGTGGATCGCCTGTCTTTCATCAGGCAAAGC
  TCCAAGGTCAAGTTCACCAGCGCTGTCAAGCTCTCAGAAGGTGGACCAGGGAGTGGGATGGAGAATGGAC
  GAGAAGAGGAGGAGAATTTCTTCAAGCGTCTTGGCTGCCACAGTTTCGATGACCACCTTTCACCCAACCA
  AGATGGTGGGAAAAGCAAAAACGTGGTGAATCTGGGAGCAATCCGACAAGGCATGAAACGTTTTCAATTC
  CTGTTGAACTGCTGTGAGCCAGGGACAATTCCTGATGCATCCATCCTAGCTGCTGCCTTGGACTTAGAAG
  CTCCTGTGGTGGCCAGAGCAGCTCTGTTCCTCGAATGTGCCCGTTTTGTCCACCGGTGCAACCGTGGCAA
  TTGGCCCGAGTGGATGAAAGGGCACCACGTGAACATCACCAAGAAAGGCCTTTCCCGGGGCAGGTCTCCC
  ACCGTGGGCAACAAGCGGAACCAGAAGCTTCAGTGGAGTGCTGCCAAGCTCTTCTACCAGTGGGGAGATG
  CAATTGGCATCCGATTGAATGAGCTGTGCCATGGAGAGAGCGAGAGTCCTGCCAACCTGCTCGGCCTTAT
  CTATGATGAGGAAACCAAGAGAAGACTGCGGAAGGAGGATGAGGAGGAAGACTTTTTAGATGACAGTACT
  GTGAACCCCTCTAAATGTGGCTGTCCCTTTGCCTTGAAGATGGCAGCATGCCAACTTCTCCTGGAGATAA
  CCACCTTCCTGAGGGAGACTTTTTCATGCCTGCCTAGACCTCGCACTGAGCCCCTCGTGGACTTGGAAAG
  CTGCAGGCTTCGTCTGGACCCTGAATTGGACCGGCACAGATATGAGAGGAAGATCAGCTTTGCAGGAGTT
  CTGGATGAAAATGAAGACTCAAAAGATTCTCTGCACAGCAGCAGCCACACCATCAAATCAGACGCAGGTG
  CTGAAGAGAAGAAAGTTCCCAGCAGGAAGATCAGGATAGGAGGTTCTCGACTGCTCCAGATTAAAGGAAC
  CCGCAGTTTCCAGGTGAAGAAGGGGGGTTCCTTGTCCAGCATTCGCCGAGTCGGCAGCTTAAAGAGCAGC
  AAGTTATCACGGCAGGACTCAGAGTCTGAGGCTGAGGAGCTGCAGCTGTCCCAGAGCAGGGACACTGTCA
  CTGACCTAGAAGGAAGTCCTTGGAGTGCAAGTGAACCCAGCATTGAGCCTGAGGGACTGAGCAATGCCGG
  CACAGAGGAAAACTACCACAGAAACATGTCGTGGCTTCACGTCATGATCTTACTCTGCAATCAACAAAGT
  TTCATTTGTACACATGTGGACTACTGCCATCCACACTGCTACCTGCACCACAGCCGCTCCTGTGCCCGGC
  TGGTCAGGGCCATTAAATTGCTGTATGGGGACAGTGTGGACTCCCTGCGTGAGAGCAACCACATCAGCAA
  CGTGGCTCTGAGGGGCAAGAAACAGAAAGAGTGCTCAGATAAGTCATGCCTGAGGACACCTTCCCTGAAG
  AAGAGAGTTTCGGATGTCAACCTGGAAGGAAAAAAGGACTCGGGAATGCTGAAGTACATCAGGTTTCAGG
  TGATGAGCTTGTCACCTGCTCCCTTGTCTCTGCTCATCAAGGCTGCTCCGATTCTGACAGAGGAGATGTA
  TGGAGACATCCAGCCAGCTGCCTGGGAACTGCTACTCAGTATGGATGAGCACATGGCTGGGGCAGCAGCC
  GCCATGTTCCTGTTGTGTGCTGTGAAGGTCCCCGATGCTGTGTCAGACATGCTGATGTCCGAGTTCCATC
  ATGCAGAGACTGTACAGAGGCTGAATGCTGTCCTCAAGTTTCACACTCTCTGGAGGTTTCGCTATCAGGT
  CTGGCCTAGGATGGAGGAGGGAGCACAGCAGATTTTTAAGATCCCGCCTCCCAGCATAAACTTTACCCTG
  CCATCACCAGTACTTGGAATGCCATCTGTCCCAATGTTCGACCCTCCGTGGGTCCCTCAGTGCAGCGGGA
  GTGTCCAGGACCCCATTAACGAAGACCAGTCTAAATCCTTCTCTGCCCGGGCAGTGTCCCGCTCCCATCA
  GAGGGCAGAGCACATCTTAAAGAACTTGCAGCAGGAGGAAGAGAAGAAACGCCTTGGTCGTGAGGCGAGC
  CTCATCACCGCCATCCCCATCACCCAAGAGGCTTGCTATGAGCCCACCTGCACACCCAACTCAGAGCCTG
  AGGAAGAAGAAGAAGTCGCCAATCTGACATCCCGACGGCTGTCTGTGAGTCCATCCTGCACCTCCAGTAC
  GTCGCACAGGAATTATTCCTTCCGCAGAGGGTCAGTCTGGTCCGTGCGTTCAGCAGTCAGTGCTGAAGAT
  GAGGAGCACGCCACTGAGCACACCCCGAACCACCATGTGCCTCAGCCTCCGCAAGCAGTGTTCCCAGCAT
  GCATCTGTGCCGCAGTTCTTCCCATTGTTCATTTAATGGAGGATGGCGAGGTGCGGGAAGATGGCGTGGC
  AGTCAGTGCTGTGGCCCAGCAAGTCTTGTGGAACTGTCTAATTGAAGATCCATCAACAGTTCTTCGACAT
  TTTCTGGAAAAACTGACCATCAGCAATAGACAAGATGAGCTAATGTACATGCTCCGAAAACTTCTCTTAA
  ATATTGGAGACTTTCCAGCTCAAACATCACACATCCTGTTCAACTACCTGGTGGGGTTAATCATGTACTT
  TGTGAGGACCCCGTGTGAGTGGGGTATGGATGCCATCTCTGCCACGCTGACCTTCCTGTGGGAGGTGGTC
  GGATATGTGGAGGGCCTCTTCTTCAAGGATCTCAAGCAGACGATGAAGAAGGAGCAATGCGAAGTGAAGC
  TGCTGGTCACTGCTTCCATGCCAGGTACCAAAACCTTGGTAGTCCATGGGCAGAATGAGTGTGACATCCC
  AACACAGCTGCCAGTACATGAAGACACTCAGTTTGAAGCCCTGCTGAAGGAGTGTCTGGAGTTTTTCAAC
  ATCCCAGAATCCCAGTCAACGCATTATTTTCTCATGGATAAACGATGGAACCTCATCCACTATAACAAGA
  CCTATGTTCGAGACATTTATCCCTTCCGGAGGTCCGTCTCGCCACAGCTGAATCTCGTCCACATGCATCC
  GGAGAAGGGGCAGGAGCTCATTCAGAAGCAGGTGTTCACCCGGAAGCTGGAGGAAGTAGGGCGGGTTTTG
  TTCCTCATCTCCCTTACCCAGAAGATCCCCACGGCCCACAAGCAGTCACATGTCTCCATGCTCCAGGAGG
  ACCTTCTGCGGCTGCCCTCCTTCCCGCGGAGTGCAATAGACGCTGAGTTTTCTCTCTTCAGTGACCCGCA
  AGCTGGGAAGGAACTGTTTGGCCTCGACACCCTGCAGAAAAGCTTGTGGATCCAACTCCTGGAGGAGATG
  TTCCTGGGCATGCCGAGCGAGTTTCCCTGGGGAGACGAAATCATGCTTTTTCTCAATGTGTTCAATGGGG
  CTCTGATTCTCCACCCAGAAGACAGTGCCCTGCTCAGGCAGTACGCAGCCACTGTCATCAACACAGCTGT
  CCACTTCAATCACCTGTTCTCTCTTAGTGGCTACCAGTGGATTCTCCCCACCATGCTGCAGGTATACTCA
  GACTATGAAAGCAACCCCCAGCTGCGTCGCGCCATCGAATTTGCCTGCCACCAGTTCTACATCCTACACA
  GAAAGCCCTTTGTGCTCCAACTGTTTGCTAGTGTGGCCCCTCTTCTGGAGTTCCCGGATGCTGCCAATAC
  AGGGTCCAGCAAAGGTGTGTCTGCTCAGTGCCTGTTTGACTTGCTGCAGTCTCTGGAGGGAGAAACCACT
  GACATATTGGACATTCTAGAGCTGGTTAAAGCTGAGAAGCCCCTTAAGTCACTAGATTTCTGCTATGGGA
  ATGAAGACCTGACATTCTCCATCAGTGAAGCCATCAAGCTCTGCGTCACCGTGGTGGCTTACGCTCCTGA
  GTCATTCCGAAGCCTTCAGATGCTAATGGTCTTGGAGGCTTTAGTTCCATGCTACCTACAGAAGATGAAG
  AGGCAGACGTCCCAGGTAGAGACAGTGCCTGCTGCCCGGGAGGAGATTGCTGCCACAGCTGCTCTGGCCA
  CATCACTACAAGCCCTTTTGTACAGTGTGGAGGTCCTCACCAGGCCCATGACAGCCCCACAGATGAGCAG
  GAGTGACCAAGGTCACAAGGGAACCACCACAGCCAACCATACCATGTCGTCTGGAGTGAACACCAGGTAC
  CCGGAGCAAGGAGCCAAGCTGCACTTTATCAGGGAAAACCTCCATTTACTAGAGGAAGGGCAAGGCCTTC
  CCAGAGAAGAACTAGATGAACGAATTTCTCGAGAAGAATTCAGAAGACCCCGGGAATCTCTGCTGAACAT
  TTGCACGGAATTCTATAAGCACTGCGGGCCGAGGCTGAAGATCCTGCAAAACCTAGCTGGGGAGCCACGG
  GTCACTGCCCTGGAGCTGCTGGATGTGAAGTCTCACATGAGGCTGGCAGAAATTGCACACTCCCTCCTGA
  AGCTGGCACCATATGACACCCAGACAATGGAGAGCCGAGGCCTTCGGCGCTACATCATGGAGATGCTCCC
  CATTACTGATTGGTCAGCAGAGGCTGTGAGGCCAGCTCTTATCCTCATTCTAAAGAGACTGGATAGAATG
  TTCAACAAAATCCATAAGATGCCCACCTTGAGGCGACAGGTTGAATGGGAGCCTGCCAGCAGTTTGATTG
  AAGGGGTTTGTTTGACACTTCAGAGGCAGCCAATCATATCCTTCCTGCCTCACCTTAGGTCACTGATCAA
  TGTCTGTGTCAATCTGGTGATGGGAGTGGTAGGACCTTCCAGTGTTGCGGATGGATTACCCCTTCTTCAT
  CTCAGCCCTTATCTCTCACCACCTCTGCCCTTCAGCACAGCTGTTGTCCGGCTTGTAGCATTGCAGATAC
  AGGCTTTAAAAGAAGATTTTCCTTTAAGCCATGTGATCTCCCCATTCACCAATCAAGAGCGAAGGGAGGG
  GATGCTTTTAAATCTGCTCATCCCATTTGTGCTCACAGTAGGATCTGGAAGCAAAGATAGCCCGTGGCTG
  GAGCAGCCCGAGGTACAGCTACTGCTGCAGACTGTCATTAATGTGCTCCTGCCCCCTCGGATCATCAGCA
  CATCCAGGAGCAAGAACTTCATGCTGGAGAGCTCCCCAGCACACTGCTCTACCCCCGGGGATGCAGGCAA
  AGACTTGCGCAAGGAAGGGCTGGCTGAGTCCACCAGCCAGGCAGCATATTTAGCTCTCAAGGTTATTCTC
  GTCTGCTTCGAGAGGCAGCTGGGCAGCCAGTGGTACTGGCTGAGCCTGCAGGTGAAGGAGATGGCTCTGC
  GAAAGGTGGGCGGCCTGGCCCTGTGGGACTTCCTCGACTTCATCGTGCGCACCCGGATACCCATCTTCGT
  TCTCTTGCGCCCTTTCATCCAATGCAAGCTATTGGCCCAACCAGCAGAAAATCACGAGGAGCTTTCTGCC
  CGGCAACACATCTCCGACCAGCTGGAGCGGCGCTTCATCCCCCGCCCTTTATGCAAGAGCTCTCTCATTG
  CAGAGTTCAATAGCGAGCTGAAAATTCTGAAAGAGGCAGTCCACAGTGGATCGGCCTACCAAGGAAAGAC
  ATCTATCAGCACTGTAGGCACATCCACTTCTGCCTACCGCCTGAGCCTGGCCACCATGTCTCGCTCCAAC
  ACAGGCACAGGCACTGTCTGGGAGCAGGACAGCGAACCATCCCAACAGGCTTCCCAAGACACCCTCAGTC
  GGACCGATGAGGAGGACGAGGAAAATGACTCTGTAAGCATGCCCAGTGTGGTAAGTGAACAGGAAGCTTG
  TCTCCTCAGCACCATTGGAAGGAGGCGGTTCTCCAGCCACGTCTCCAGCATGTCTGCACCTCAGGCTGAG
  GTGGGCATGTTACCCAGTCAAAGTGAACCTAATGTCCTCGATGACTCCCAGGGCCTGGCCGCCGAGGGCA
  GCCTCTCTAGGGTGGCAAGTATACAGAGTGAACCTGGACAGCAGAACGTCCTCCTACAGCAGCCACTGGG
  GAGGAAGAGGGGCCTGAGGCAGCTAAGACGCCCTCTCCTGTCAAGGCAGAAGACTCAAACGGAACCCAGA
  AACCGCCATGGAGCTCGACTGTCCACCACTCGCAGGAGCATTCAACCTAAAACAAAACCATCTGTTGATC
  AGAAGCGATCTGTGACATTCATTGAGGCTCAGCCAGAGCCAACAGCTGCCCCAACAGACATATTTCCTGC
  CACGGGCCAACCACAGAGCTGCAGCCCAGGCCGAGCTAGGAAGCCAGAAGGAACAGAGAAGCCAGTGCTC
  ACATCCTCCCCCGCCATTATCATTGCAGATCTTCATAGCCTGTCTCCCAAGCAGAGTGAGCCCCTTCTTG
  CTGAAGAAGGAGAGAAAAAGGAGGACGAAGAAATACAAGGTGCCACAGCTCACTGCCCCCTCTCCACTCA
  ACTGTCAGACCCGGATGACTTCACTGGCCTTGAAACATCCAGCCTCCTACAGCATGGAGACACTGTCCTT
  CATATCAGTGAGGAGAACGGCACGGAGAATCCCCTGCTGTCCAGCCAGTTCACTTTCACTCCTCCCGAGC
  TGGGAGACACAGACTCAGCACTAGATGAGTCCCACGTTTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_175510
• Insert Size: 9981 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_175510.3, NP_780719.2
• RefSeq Size: 13533 bp
• RefSeq ORF: 9981 bp
• Locus ID: 329178
• UniProt ID: Q8BLN6
• Cytogenetics: 1 C3
• Gene Summary: Component of the NALCN sodium channel complex, required for channel regulation. This complex is a cation channel activated by neuropeptides substance P, neurotensin, and extracellular calcium that regulates neuronal excitability by controlling the sizes of NALCN-dependent sodium-leak current. UNC80 is essential for NALCN sensitivity to extracellular calcium.[UniProtKB/Swiss-Prot Function]