Aox3 (NM_023617) Mouse Untagged Clone

CAT#: MC224263

Aox3 (untagged) - Mouse aldehyde oxidase 3 (Aox3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Aox3
• Synonyms: 1200011D03Rik; AI326299; Aoh1; Aoh2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224263 representing NM_023617
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCTCCTTCTAAGGAGTCAGATGAGCTTATTTTCTTTGTGAATGGAAAAAAGGTCACCGAGAGGAATG
  CAGACCCTGAGGTTAATTTATTGTTCTACTTGAGAAAAGTCATCCGACTCACAGGGACAAAGTATGGCTG
  TGGAGGAGGTGACTGTGGCGCCTGCACAGTGATGATCTCAAGATACGACCCCATCTCCAAAAGGATCAGT
  CATTTCTCTGCCACTGCCTGCCTGGTTCCCATCTGCTCTCTCCATGGGGCTGCTGTCACTACAGTAGAAG
  GCATAGGAAGCACCAAAACCAGGATACACCCTGTCCAGGAAAGGATTGCCAAAGGCCATGGTACCCAGTG
  TGGGTTCTGCACTCCCGGGATGGTGATGAGCATCTATACTCTCCTGAGGAACCACCCAGAGCCCTCCACA
  GAACAGATAATGGAAACCCTGGGCGGGAATCTATGCCGCTGCACTGGATACAGGCCCATTGTGGAGAGTG
  CGAAAAGTTTCTGCCCGAGTTCAACTTGCTGCCAGATGAATGGGGAAGGGAAATGTTGCTTGGATGAAGA
  AAAAAACGAGCCTGAGAGAAAAAACAGTGTTTGCACCAAGTTGTATGAAAAAAAAGAATTTCAGCCCTTG
  GATCCAACTCAGGAGCTTATATTTCCACCTGAGCTGATGAGGATGGCCGAGGAGTCCCAAAATACAGTTC
  TGACTTTTCGTGGGGAAAGGACTACCTGGATTGCCCCAGGAACCCTAAATGACCTTCTGGAACTGAAAAT
  GAAGCATCCCAGCGCTCCACTTGTGATTGGCAACACCTATCTGGGGCTTCATATGAAGTTCACAGACGTA
  TCTTATCCAATTATCATCTCTCCTGCAAGGATCTTAGAATTATTTGTGGTGACTAATACAAAGCAAGGGC
  TGACACTGGGCGCAGGCCTCAGCCTGACCCAGGTGAAGAACGTCTTGTCTGACGTGGTCTCCAGACTCCC
  TAAGGAGAAGACGCAGATATACTGTGCTCTCCTGAAGCAGCTGAAGACCCTGGCTGGGCAGCAGATCAGG
  AATGTGGCCTCCTTAGGTGGTCATATTATCAGTAGACTGCCGACCTCTGACCTCAACCCTATTTTGGGCA
  TAGGCAATTGCATCCTCAATGTTGCCTCAACAGAAGGAATACAGCAAATCCCTCTGAATGATCATTTTCT
  CGCTGGAGTTCCAGATGCAATCCTGAAGCCAGAGCAAGTGCTCATCTCCGTTTTTGTGCCACGCTCCAGC
  AAGTGGGAGTTTGTATCAGCCTTCAGACAGGCCCCTCGTCAGCAAAACGCGTTTGCAACAGTGAATGCTG
  GAATGAAAGTCGTTTTCAAGGAGGACACAAACACCATTACAGACTTGGGGATCTTATATGGAGGGATTGG
  TGCCACCGTAATCAGCGCAGATAAGTCCTGCCGGCAGCTGATTGGAAGGTGCTGGGATGAAGAAATGCTG
  GATGATGCTGGCAAGATGATTTGTGAGGAAGTCTCCCTCCTGATGGCAGCCCCTGGAGGGATGGAGGAAT
  ACCGAAAGACTCTTGCCATCAGTTTCCTCTTCATGTTTTACTTAGACGTGTTGAAGCAGTTAAAGACGAG
  GGACCCCCACAAGTACCCTGACATCTCACAGAAACTCCTACACATTCTGGAAGACTTCCCTTTAACCATG
  CCTTATGGGATGCAGTCATTTCAGGATGTAGACTTCCAACAGCCTCTGCAAGACCCAATCGGACGTCCCA
  TCATGCATCAGTCTGGCATTAAACACGCCACAGGAGAGGCAGTATTTTGTGATGATATGTCTGTGTTGCC
  TGGGGAACTCTTCTTGGCAGTGGTAACCAGCAGCAAGTCACATGCTAAAATCATCTCTCTTGATGCCTCC
  GAGGCCTTGGCGTCACTTGGTGTGGTTGATGTGGTAACAGCTCGAGATGTGCCTGGTGACAATGGCAGAG
  AAGAGGAAAGCCTATATGCACAGGATGAGGTGATCTGCGTGGGTCAAATTGTGTGTGCTGTGGCCGCTGA
  CTCTTATGCTCATGCCCAGCAGGCCGCAAAAAAAGTGAAGATTGTCTATCAAGACATAGAGCCCATGATT
  GTGACAGTGCAGGATGCACTGCAATATGAATCATTCATTGGACCTGAAAGAAAACTAGAACAAGGAAATG
  TTGAGGAAGCATTTCAATGTGCCGATCAAATCCTCGAAGGGGAGGTGCACTTGGGAGGCCAGGAGCATTT
  TTACATGGAGACTCAAAGCGTACGTGTGGTCCCCAAGGGAGAGGATAAGGAGATGGACATCTATGTGTCA
  AGCCAGGATGCTGCATTTACACAGGAAATGGTGGCTCGCACCTTGGGCATCCCAAAGAATAGGATCAACT
  GCCATGTGAAAAGGGTTGGTGGAGCCTTCGGAGGGAAAGCAAGCAAGCCTGGGCTCCTGGCATCCGTGGC
  AGCTGTAGCCGCACAGAAGACCGGCCGCCCAATACGTTTCATTCTAGAGCGTAGGGATGACATGTTGATA
  ACTGGAGGACGTCACCCACTACTCGGGAAATACAAGATTGGCTTCATGAACAATGGGAAAATCAAGGCGG
  CAGACATCCAGCTTTATATCAATGGAGGCTGCACCCCAGATGATTCTGAACTGGTGATAGAATATGCTTT
  GCTCAAACTGGAAAATGCTTACAAGATCCCCAACCTCCGTGTCCGAGGTCGAGTCTGTAAGACCAACTTG
  CCTTCCAATACAGCGTTTCGAGGATTTGGCTTTCCCCAGGGGGCATTTGTAACAGAAACCTGTATGTCCG
  CTGTGGCAGCCAAATGCCGCTTACCACCAGAGAAGGTTCGAGAGCTAAACATGTACAGAACAATCGATAG
  GACAATTCACAACCAAGAGTTTGACCCAACGAATCTGCTACAGTGCTGGGAGGCATGTGTGGAAAATTCT
  TCCTACTATAACAGGAAAAAAGCTGTGGATGAATTTAACCAACAGAGATTTTGGAAGAAGAGAGGAATTG
  CCATCATCCCCATGAAATTCTCAGTTGGATTTCCAAAGACATTTTATTATCAGGCTGCCGCTTTGGTCCA
  GATCTACACAGATGGGTCTGTACTAGTTGCTCATGGTGGTGTTGAACTGGGACAAGGTATTAACACCAAA
  ATGATACAGGTGGCCAGCCGTGAATTAAAGATACCTATGTCTTATATACACCTGGATGAGATGAGCACTG
  TGACCGTCCCCAACACGGTTACCACTGGAGCATCCACCGGTGCCGATGTCAACGGGAGAGCTGTTCAGAA
  TGCCTGTCAGATCCTTATGAAGCGTCTGGAACCCATCATCAAGCAGAATCCTAGTGGTACCTGGGAAGAA
  TGGGTTAAGGAAGCTTTTGTTCAAAGCATTAGCCTCTCGGCCACTGGATATTTTAGGGGTTACCAAGCTG
  ACATGGACTGGGAGAAGGGAGAAGGTGACATTTTTCCCTATTTTGTTTTTGGAGCTGCCTGTTCTGAGGT
  TGAAATTGATTGTCTGACGGGAGCTCACAAGAACATTAGAACCGACATTGTTATGGATGGATCATTCAGT
  ATAAATCCTGCTGTGGACATAGGCCAGATTGAAGGGGCATTTGTTCAAGGTCTTGGACTGTATACTCTAG
  AGGAACTGAAATATTCACCTGAAGGAGTCCTATACACTCGTGGTCCACACCAGTACAAAATAGCATCAGT
  TACCGACATCCCAGAAGAATTCCATGTATCACTGTTGACACCAACCCCAAACCCAAAAGCCATCTACTCT
  TCTAAGGGCCTTGGCGAAGCTGGAACGTTTCTGGGCTGTTCTGTGTTCTTCGCTATTGCCGCGGCCGTGG
  CTGCAGCTCGAGAGGAGAGAGGCTTGTCCCCAATTTGGGCCATAAACAGCCCTGCCACAGCAGAAGTGAT
  CCGCATGGCCTGTGAGGACCAGTTCACGAACCTGGTTCCACAAACGGATTCTAAATGCTGTAAGCCGTGG
  TCCATCCCAGTTGCCTAG
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-RsrII
• ACCN: NM_023617
• Insert Size: 4008 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_023617.2, NP_076106.2
• RefSeq Size: 4360 bp
• RefSeq ORF: 4008 bp
• Locus ID: 71724
• UniProt ID: G3X982
• Cytogenetics: 1 28.96 cM
• Gene Summary: Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and phthalazine, as well as aldehydes, such as benzaldehyde, retinal and pyridoxal. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor.[UniProtKB/Swiss-Prot Function]