Tlr13 (NM_205820) Mouse Untagged Clone

CAT#: MC223016

Tlr13 (untagged) - Mouse toll-like receptor 13 (Tlr13), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Tlr13
• Synonyms: AI666735; Gm713
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223016 representing NM_205820
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGTGGGCTCTACAGGATCCTGGTCCAGCTGGAACAAAGTCCATATGTGAAGACCGTGCCTTTGAACA
  TGAGAAGGGATTTTTTTTTCCTGGTTGTAACCTGGATGCCTAAGACAGTCAAGATGAATGGGAGCAGCTT
  TGTGCCATCTCTACAGCTCCTGCTCATGTTAGTAGGATTTTCTCTGCCGCCTGTGGCAGAGACATATGGG
  TTCAACAAGTGCACACAGTATGAATTTGATATTCACCATGTGCTCTGCATTAGGAAGAAGATCACCAACT
  TGACAGAGGCCATTAGTGACATACCTAGATATACTACTCACCTTAACCTCACACACAACGAAATTCAAGT
  CCTCCCTCCCTGGAGTTTTACCAATCTGTCTGCTCTGGTGGACTTGAGACTAGAGTGGAACTCAATTTGG
  AAGATCGACGAAGGTGCCTTTAGGGGACTTGAAAATTTGACTCTGCTGAATTTAGTGGAAAATAAGATTC
  AAAGTGTGAATAACTCCTTTGAGGGCCTGTCCAGCCTGAAGACCCTGCTCCTGAGCCATAATCAGATTAC
  CCATATTCACAAAGACGCCTTCACTCCTCTAATCAAATTGAAATATTTGAGCCTATCTCGAAACAACATT
  AGCGATTTTTCTGGTATTCTTGAAGCAGTCCAGCATCTTCCATGCCTGGAGCGCCTTGATCTAACTAACA
  ACAGCATCATGTACTTGGACCACAGCCCTAGGTCACTGGTTTCTCTGACCCACCTGAGTTTTGAGGGGAA
  CAAACTAAGGGAGTTAAACTTCTCTGCTTTGTCATTACCTAACTTAACCAATCTAAGTGCTTCCCGGAAT
  GGCAATAAAGTCATTCAGAATGTGTATCTTAAAACTCTGCCCCAACTTAAAAGCTTGAATCTGAGTGGAA
  CGGTGATAAAATTGGAAAATCTTTCGGCCAAACACCTGCAGAATCTAAGAGCTATGGATCTCAGTAATTG
  GGAGCTTAGACATGGTCACTTAGATATGAAAACTGTTTGTCACCTGCTCGGAAACCTACCCAAGTTAGAG
  ACACTGGTTTTTCAGAAAAATGTCACCAATGCAGAGGGCATTAAGCAGCTGGCAAAGTGCACCAGGCTCT
  TGTTCCTTGACCTGGGTCAAAACAGTGACTTGATTTATCTCAATGACAGCGAGTTCAATGCTCTGCCCAG
  TCTCCAAAAACTGAATTTGAACAAGTGCCAGCTCTCCTTCATCAACAACAGGACCTGGAGTTCCTTGCAG
  AACTTGACCAGCCTAGATCTGAGCCACAACAAGTTTAAAAGCTTTCCAGATTTTGCATTTTCCCCCTTGA
  AGCACTTGGAGTTTCTCTCTCTTTCAAGAAACCCCATCACAGAACTCAATAATCTGGCCTTTAGTGGGCT
  ATTTGCACTGAAGGAGCTCAACTTGGCTGCATGTTGGATTGTAACAATTGACAGGTATTCCTTTACTCAG
  TTTCCAAACTTAGAGGTCTTAGATCTTGGAGACAACAATATTCGGACTCTCAACCACGGAACCTTCCGAC
  CTCTGAAAAAACTCCAGTCTTTGATTCTTTCCCACAACTGCCTAAAAATCCTGGAGCCAAATTCGTTTTC
  TGGTCTCACTAACCTACGTTCCCTTGACCTGATGTACAACAGCTTGTCATATTTTCATGAACACCTTTTC
  TCGGGCCTTGAAAAGCTTCTGATTTTGAAACTTGGTTTTAATAAGATCACATATGAAACTACTAGGACCC
  TTCAGTATCCTCCATTTATAAAGCTCAAGTCTTTGAAACAGCTTAACCTAGAAGGACAAAGACACGGGAT
  TCAGGTTGTTCCGAGCAACTTTTTCCAAGGATTGGGTAGTTTGCAGGAGTTACTCTTAGGAAAAAATCCC
  TCTGTATTCCTGGACCACCACCAATTTGACCCTCTGATTAACCTCACAAAGTTGGATATCTCAGGAACAA
  AAGATGGAGATCGAAGCCTCTATTTAAATGCTTCCTTATTCCAAAACCTCAAAAGGCTAAAGATCCTCCG
  CCTTGAAAATAACAACTTAGAGTCACTGGTTCCTGACATGTTCTCCAGCTTACAGAGCCTCCAGGTCTTT
  TCTTTAAGATTCAACAACTTGAAGGTCATTAATCAAAGTCATCTGAAGAATCTGAAATCACTGATGTTTT
  TTGATGTCTATGGGAACAAACTTCAGTGCACCTGTGACAATTTGTGGTTCAAGAACTGGTCAATGAACAC
  AGAGGAGGTCCACATCCCCTTCCTCCGGAGCTATCCCTGTCAGCAGCCAGGCAGCCAGAGTTTACTTATA
  GATTTTGATGATGCCATGTGTAATTTTGACTTGGGAAAGGTCTACTTCTTATGTTCCTTCAGTATGGTCC
  TCAGCACCATGGTCTTCTCTTGGTTCAGTACCAAGATGATTGCATCTCTGTGGTATGGTTTGTACATATG
  TAGGGCCTGGTACCTCACTAAATGGCACAAAACGGAGAAGAAGTTCTTATATGATGCGTTTGTCTCTTTC
  TCGGCCACTGATGAGGCATGGGTATACAAAGAGCTTGTTCCAGCCCTAGAACAAGGCAGCCAGACCACCT
  TTAAACTCTGTCTTCACCAACGGGATTTTGAACCAGGCATTGATATCTTCGAGAACATCCAGAATGCTAT
  TAACACAAGCAGGAAAACCTTGTGCGTAGTCAGTAACCACTACCTACACAGTGAATGGTGCCGACTTGAA
  GTCCAGCTGGCTAGCATGAAGATGTTTTATGAGCACAAGGATGTCATTATCTTGATCTTCCTTGAAGAGA
  TTCCGAACTATAAGCTGTCCAGCTACCACCGACTCAGGAAACTCATAAACAAACAGACGTTTATCACTTG
  GCCGGACAGTGTTCACCAGCAGCCACTTTTCTGGGCTCGCATCAGAAATGCGTTGGGCAAGGAGACTGTG
  GAGAAAGAAAATACACATCTAATTGTTGTTGAGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_205820
• Insert Size: 2976 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_205820.1, NP_991389.1
• RefSeq Size: 4014 bp
• RefSeq ORF: 2976 bp
• Locus ID: 279572
• UniProt ID: Q6R5N8
• Cytogenetics: X D
• Gene Summary: Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus; however, these data require additional evidences.[UniProtKB/Swiss-Prot Function]