Wdr63 (NM_172864) Mouse Untagged Clone

CAT#: MC222671

Wdr63 (untagged) - Mouse WD repeat domain 63 (Wdr63), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Wdr63
• Synonyms: 4931433A13Rik; IC140; Ida7
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC222671 representing NM_172864
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCACCCAAGCCACCGAAGAGCCCCAAGGGCCAGAAAAAGGGCAAAAAGAATATGAAGCAACAGTTAC
  TTGTTCCTGAGGAAGAGGAGCCCATGAACATGGAGAGCATGGGCCATCCAGAAATTTATCCACTAGTATT
  AACTACCAAGACCCAGGAAATATTCAACTGTCGAGTAGATGAAGATATGACAGACGAACAAACGTATAAG
  CTTATCAAAAAGGAAGATATCTTGGCAGACTTGCAAAACCGAGCCGCAGTATCTGACTTCCACCCAGTCA
  AAAAAATTGTCCGGGAGTACCCAGGGGAGGAACTTCTCCTCGTTTATGACAAAGACTTCAAGTATGGACT
  TAACTTTTACCTCATTGGAACAGAGGACGGCAAGGAGAACTTTTTAAAGCCACCAGAAGTGCCAGAGGAA
  CAAGAAGAGCCCAAGGAGCACGTCCAAGAAGACGTGTACGTCTACAATCCTCCCGTCTCCAAGCCATGGG
  TGTCGCTGGGCAGCGAGAAAGAAATTGAGGAAGAATCTGTCCAGGAATCAGGAAAGCGGGTGACCTACAT
  GATTTCTAGAAAACGGAGTGAATTTGGTGCACCAGTGACTTTCAGTGACCAGAATGCCTCTAGCGTAAAA
  GATGCCTACATTGAGTGTACGTCTTACCCAGAGAAAAATTACACCCTCTCACAAGTTGAGAAAGATGTCG
  GCTTGCAAGTCATTGCTGAAGTCAAGGACACAAGCACGCAGACAAAATGGGCTTTTCCTAAAAATGCTAC
  CACTCAGTATTATCCAAGAGAATTCTCAGAAGAGGAAAAAAGCCTCATCGGAAAATCAAAATCTTTGGTC
  GACTTTTTCAACAATGTGTCCACAAGCGTTGAAGTAGCCCTGCAGCAGAATGAGATCATGAACACGTTTA
  TCGACGACTGGAAGAACCTCGCAGAGGAGGAGAGCACCTTTGGGGACAAGACTGACACCCATCTGAAGGA
  GTACCAGTCCTTTACAGACCTTCACAACACCATGGAGAAAATGATTACCTGTGTCTCTTGGCACCCGACC
  ATCTTCGGGCTCATAGTCGTGTCTGTGGCCGTGCGCCTCTCCTATGAAGAGAGAGTCCAGAATTCCGGCA
  GACTGCTGCTGCAGCCGTCACTGCTCCTCTTCTGGAGCTTCTCCGACCCCATCCACCCTCAGTTGATGCT
  GGAGAGCCCGGATGACATCTTCTGCTTCGAGTTCTGTCCAAGTGACCCCAATATCATCGCCGGAGGCTGC
  ATTAACGGACAGATCGTCTTGTGGGATATCACGGCACACGCGGACCGCATAGAGAACATCAAGACGGGCG
  GCCACAGAAGTAAAAAGACCTCTCTCAAGCCCATGTTTCTCCTTGAACCAGACAGCAATAAAGAATCGAT
  GTACATCAGACACTGTGCAGTGTCTTCCATTGAAAATGGCCATAGGAAAGTAATCACGGATATACACTGG
  CTGCCCGACTCATTCGAGATTAACAGGATGGGATCCGTCTTTGAGAACCGAAGTGGAATAAATTGTCAGC
  TCGTCACATGCTCAGCAGACTGCACGATTTGTTTTTGGGATATCCGGCCCCAAAAACCTGCAGTCACAGC
  TGCAGCTGCAGCCTCAGCAGCAACCACAGCCACCAACAACGCAAACTCCCAGCAATCACCGGTAGAGAAG
  AAGAAAGAAGAAAACATTGACATTCCCTTTGATGTGCCCTCGACTTTCTTGCACCTAGATCTCTCCTGGA
  AACCCCTGTCTAGATTAAAACTGTCTAAGGGTGATACAAGTTTAGACCACTGTCCAACCAAGCTGAGCCT
  GGGCGAAGACCCTTTTCTTTGCAAAATACAAGGTACGTCGTCCATTCATATTATTCTGAGAGACAAGATG
  TTAAGTCAGATCAAGATGGTGAAGACGTCAGAAATTAACCCCTACCAAAACCTGGAAGCAGGGATAGCCA
  ATATCCTCAAGCCGATAGAGGACTTCTGCACGAAGTTCTTCGTGGGAACAGAGGAAGGTGAGGTGATATA
  CACAGACTGGAAAATGGAGAGGGACTCTGACACCGGACGACTTATGGCCAAGAAACCTGTGAGCCTCTAC
  ACCGTCCACGATGGGGCTGTCCACACCATCCAGAGGTCGCCTTTCTTCAATGACATCGTCCTCACTGTTG
  GGGGATGGAATGTGGCTATCTGGAAGGAGGAGGTCATGACGGGACCGCTCCTTCAAACGTGCTGCGGACC
  GAAAAGGTACACGGCAGGACACTGGTCCCTGACGAGGCCTGGAGTGTTCTACATCGGCCGAGAGGACGGA
  AATGTCGATATCTGGGACCTCCTGGAGAAAACTCACGAGCCAGCCCAGTCCCAGAATATCTGCATCACCA
  TGATCACCTACATCAAACCCTGGACCTTCTCCTCTAAGCAGCAGTTTATAGCCGTAGCTGACTATTACGG
  AACACTGCACATCCTAGAAATCCCTTGGACCTTAAGTCACCCTTCCTTGAATGAGGTATCGAGTGTGAAC
  TACTACTTTGAGAGAGAAGTCAGACACCTGGAATACGTCCAGCAGCGCAAAGAAATCCGTGAGCAAGAAA
  AGATAGATATGGCCCTGGAACTGGTGAAGAAGAAAGCGAAAATCTATCAAAAGACAAAAGAGCAAATGGA
  GGCCGAGCTGAAGTTGGAATACGAGAGCTATCTGGATCTTGAGAAGTCTGTCCTCTTCGCCCTCGGCCTC
  AGCAAAGTCTCAGAGAAGAAGTCCTACTTGGATTCACATTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_172864
• Insert Size: 2772 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_172864.3, NP_766452.2
• RefSeq Size: 3082 bp
• RefSeq ORF: 2772 bp
• Locus ID: 242253
• UniProt ID: B2RY71
• Cytogenetics: 3 H2
• Gene Summary: Acts as a negative regulator of cell migration, invasion, and metastasis downstream of p53/TP53, through inhibition of Arp2/3 complex-mediated actin polymerization (By similarity). Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function (PubMed:30060180). May play a role in osteogenesis of dental tissue-derived mesenchymal stem cells (PubMed:25498833).[UniProtKB/Swiss-Prot Function]