Epc1 (NM_007935) Mouse Untagged Clone

CAT#: MC221424

Epc1 (untagged) - Mouse enhancer of polycomb homolog 1 (Drosophila) (Epc1), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Epc1
• Synonyms: 2400007E14Rik; 5730566F07Rik; A930032N02Rik; mir-1893
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221424 representing NM_007935
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAACACCATCTTCAGCGGGCTATTTCTGCACAGCAGGTGTACGGCGAGAAGCGGGATAACATGGTTA
  TTCCAGTTCCTGAAGCAGAGAGTAACATCGCTTACTATGAGTCCATATACCCTGGGGAGTTCAGGATGCC
  AAAGCAGCTCATTCACATACAGCCTTTTAGCTTGGACGCTGAACAGCCTGATTACGATCTGGATTCTGAA
  GATGAAGTATTTGTGAATAAACTGAAGAAGAAAATGGACATCTGCCCATTGCAGTTTGAGGAGATGATTG
  ACCGGCTAGAAAAAGGCAGCGGTCAGCAGCCAGTCAGTCTGCAGGAAGCCAAACTACTTCTAAAAGAAGA
  TGATGAGTTAATTAGAGAAGTTTATGAATACTGGATTAAAAAGAGGAAAACCTGCCGGGGGTCATCACTT
  ATCCCGTTGGTAAAACAGGAAAAGCGAGATGGTTCTAGCACAAATGATCCTTACGTGGCTTTTAGAAGAC
  GAACTGAGAAAATGCAAACTCGGAAAAACCGTAAGAATGATGAAGCCTCATATGAGAAAATGCTCAAGCT
  GCGCCGCGATCTCAGCCGGGCTGTCACCATCCTGGAAATGATCAAGAGACGGGAGAAGAGTAAACGGGAG
  CTGCTGCACCTGACCCTGGAAATCATGGAGAAGAGGTATAATTTAGGTGACTATAGTGGAGAGATCATGT
  CTGAGGTCATGGCACAGAGACAGCCAGTGAAGCCTACTTATGCCATCCCCATCATCCCGATTACTAACAG
  CAGCCAGTTCAAACACCAGGATGCCACGGACTCGAAGGAGTTCAAAGTTAACAAGCAAGATAAGGCTGAT
  CTTATCCGGCCGAAGCGCAAATATGAAAAGAAGCCCAAAGTCTTACCCCCATCTGCTGCCGCCCCTCAGC
  AGCAGAGTCCTGCTGCACTGCCAGGCTTCAGTGCTAAAGACTTAAACCAGTACGACTTCCCCAGCTCAGA
  TGAAGAGCCTCTGTCACAGGTTTTGTCTGGCTCTTCGGAAGCTGAGGAAGAGAATGACCCTGATGGCCCT
  TTTGCTTTCCGTAGGAAAGCAGGCTGTCAGTACTATGCTCCTCATTTAGACCAAACTGGCAACTGGCCCT
  GGACTAGCCCTAAAGATGGAGGCCTGGGGGATGTGCGATATAGATATTGCTTAACTACTCTCACCGTACC
  CCAGAGGTGTCTTGGATTTGCACGAAGACGGGTCGGACGTGGTGGAAGGGTCGTGCTGGACAGAGCGCAT
  TCAGACTATGACAGTATGTTTCACCACCTGGATTTGGACATGCTTTCCTCACCACAACCTTCTCCAGTCA
  ATCAGTTTGCCAATACCTCAGAACCCAATACCTCGGACAGATCTTCCTCTAAAGACCTCAGTCAGATACT
  AGTCGATATCAAATCATGTAGATGGCGGCACTTTAGGCCTCGGACACCATCCCTGCCTGACAGTGACAGT
  GGTGAACTCTCCAGTAGAAAGTTACACAGGAGTATCAGTCGAGCAGGAGCAGCACAGCCTGGGGCCCACA
  CGTGCAGCACCTCCACCCAGAACAGAAGTAGCAGTGGCTCAGCACACTGTGCATTCACAGCCGAACAGTA
  CCAGCAGCACCAGCAGCAGCTGGCACTCATGCAGCAGCAGCAGCTTGCGCAGACTCAGCAGCAGCAGCAA
  GCAAATAGTAGTTCCTCTGCCGCCGCGCAACAGGGTTTTGTTTCTAAGACGTTGGACTCTGCTAGTGCAC
  AGTTTGCTGCTTCTGCTTTGATGACGTCGGAACAGCTGCTGGGGTTCAAGGTGAAGGATGATGTGGTGCT
  CGGGCTCGGGGTGAATGGCGTCCTTCCTGCCTCAGGAGTATACAAGGGCTTACACCTCAGTAGCACTACA
  CCAACGGCACTTGTACATACGAGTCCTTCGACAGCAGGTTCAACTTTGTTACAGCCTTCAAATATTACAC
  AGACTTCGGGTTCCCACAGCTCACTGAGTCACCAAGTAACTGCTGCCAGCTCTGCAACAACTCAGGTTCT
  GTTTGGGAACAACATCCGATTAACTGTCCCCTCATCTGTCCCCACTGTCAACTCTGTCACCCCAATAAAC
  GCACGGCATATACCTAGGACTTTAAGTGCTGTTCCGCCATCTGCCTTAAAGCTGGCTGCTGCAGCAAATT
  GTCAAGTTTCCAAGGTCCCCTCCTCATCCTCTGTAGATTCAGTTCCAAGGGAAAATCATGAATCGGAAAA
  GCCAGCACTGAACAACATAGCAGACAACACAGTAGCAATGGAGGTGACGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_007935
• Insert Size: 2292 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_007935.2, NP_031961.1
• RefSeq Size: 3832 bp
• RefSeq ORF: 2292 bp
• Locus ID: 13831
• UniProt ID: Q8C9X6
• Cytogenetics: 18 A1
• Gene Summary: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) differs in the 5' UTR and in the 5' coding region, compared to variant 2. It encodes isoform 1 which is shorter and has a distinct N-terminus, compared to isoform 2.