Vldlr (NM_001161420) Mouse Untagged Clone

CAT#: MC220767

Vldlr (untagged) - Mouse very low density lipoprotein receptor (Vldlr), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Vldlr
• Synonyms: AA408956; AI451093; AW047288
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC220767 representing NM_001161420
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCACGTCCGCGCGCTGGGCGCTGTGGCTGCTGCTCGCGCTGTGCTGGGCGCCCCGGGACAGCGGCG
  CCACTGCAAGCGGGAAGAAAGCCAAATGTGATAGCTCCCAGTTTCAGTGCACAAATGGCCGCTGCATTAC
  CCTGCTGTGGAAATGTGATGGAGATGAAGACTGTGCGGATGGCAGCGACGAGAAGAACTGTGTAAAGAAG
  ACGTGTGCTGAGTCTGACTTCGTGTGCAAAAACGGCCAGTGTGTTCCTAACAGATGGCAGTGTGACGGGG
  ATCCTGATTGCGAAGACGGTTCTGATGAAAGCCCTGAACAGTGCCATATGAGAACATGCCGCATAAATGA
  AATCAGCTGTGGCGCCCGTTCTACTCAGTGTATCCCCGTGTCCTGGAGATGCGATGGTGAAAATGATTGT
  GACAATGGAGAAGATGAAGAAAACTGTGGCAACATAACATGTAGTGCAGATGAGTTCACTTGCTCCAGTG
  GCCGCTGCGTCTCCAGAAACTTTGTGTGCAATGGCCAGGATGACTGTGACGATGGCAGTGATGAGCTGGA
  CTGTGCTCCACCAACCTGCGGAGCCCACGAGTTCCAGTGCAGCACCTCTTCCTGCATTCCCCTCAGCTGG
  GTGTGTGATGATGACGCAGACTGTTCAGACCAATCAGACGAGTCTCTTGAGCAGTGTGGCCGTCAGCCTG
  TGATACATACCAAATGTCCTACCAGTGAGATCCAGTGTGGCTCTGGCGAGTGCATTCACAAAAAATGGCG
  GTGTGACGGAGACCCTGACTGCAAGGACGGCAGCGATGAGGTCAACTGCCCTTCTCGAACCTGCCGACCT
  GACCAGTTTGAATGTGAAGATGGTAGCTGTATCCACGGCAGCAGGCAATGCAATGGCATCCGAGACTGTG
  TTGATGGCTCTGATGAAGTCAACTGCAAAAACGTCAATCAGTGCCTGGGCCCTGGAAAGTTCAAGTGCAG
  AAGCGGGGAATGCATAGACATGAGCAAAGTATGTGACCAGGAACAAGACTGCAGAGACTGGAGTGACGAG
  CCCCTGAAGGAATGCCATATCAACGAATGCCTGGTCAATAATGGTGGCTGTTCCCATATCTGCAAAGACC
  TAGTTATAGGTTATGAGTGTGATTGTGCAGCTGGGTTTGAACTGATAGATAGGAAAACCTGTGGAGATAT
  TGATGAATGCCAAAACCCGGGGATCTGCAGTCAAATTTGTATCAACTTAAAAGGCGGTTACAAGTGTGAA
  TGTAGTCGTGGCTATCAAATGGATCTTGCCACTGGCGTGTGCAAGGCAGTAGGCAAAGAGCCGAGTCTGA
  TCTTCACTAATCGAAGAGACATCAGGAAGATTGGCCTAGAGAGAAAGGAATACATCCAACTTGTAGAGCA
  ACTAAGGAACACGGTGGCTCTCGATGCGGACATTGCAGCTCAGAAGCTGTTTTGGGCTGATCTCAGCCAG
  AAGGCCATCTTCAGTGCCTCAATTGATGACAAGGTTGGTAGACATTTTAAAATGATCGACAATGTCTATA
  ATCCTGCAGCCATTGCTGTTGATTGGGTGTACAAGACCATCTACTGGACTGATGCGGCTTCTAAGACTAT
  TTCAGTAGCTACCCTAGACGGAGCCAAGAGGAAGTTCCTGTTTAATTCTGACTTGCGAGAGCCTGCCTCC
  ATAGCTGTGGATCCGTTGTCGGGCTTTGTTTACTGGTCAGACTGGGGCGAGCCAGCTAAAATAGAAAAAG
  CAGGAATGAATGGATTTGATAGACGTCCTCTGGTGACGGAGGACATCCAATGGCCTAATGGAATTACACT
  CGACCTTGTCAAAAGCCGCCTCTACTGGCTGGATTCCAAGTTGCACATGCTCTCTAGTGTGGACCTGAAT
  GGTCAAGATCGTAGGATAGTGCTCAAGTCTCTGGAGTTCCTAGCTCATCCTCTTGCACTCACCATATTTG
  AGGATCGCGTCTACTGGATAGATGGAGAAAATGAAGCAGTGTACGGTGCCAATAAATTCACTGGGTCAGA
  GCTGGCCACTCTAGTGAATAATCTCAATGATGCCCAAGACATCATTGTCTACCATGAACTCGTCCAGCCG
  TCAGGTAAAAACTGGTGTGAAGACGATATGGAGAATGGAGGATGTGAATATCTCTGCCTGCCAGCACCAC
  AGATCAATGACCACTCTCCAAAATATACCTGTTCCTGTCCCAATGGGTACAATCTCGAAGAAAATGGACG
  AGAGTGTCAAAGGATCAATGTGACCACAGCAGTATCAGAAGTCAGTGTTCCCCCAAAAGGGACTTCAGCT
  GCCTGGGCCATCCTTCCTCTCTTGCTCTTAGTGATGGCAGCAGTAGGTGGCTACTTGATGTGGAGGAATT
  GGCAACATAAAAACATGAAAAGCATGAACTTTGACAATCCTGTGTACTTGAAGACCACTGAAGAGGACCT
  GTCGATAGACATTGGTAGACACAGCGCTTCTGTAGGACACACATACCCAGCAATATCAGTTGTAAGCACA
  GATGATGATCTGGCTTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001161420
• Insert Size: 2538 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001161420.1, NP_001154892.1
• RefSeq Size: 8243 bp
• RefSeq ORF: 2538 bp
• Locus ID: 22359
• UniProt ID: P98156
• Cytogenetics: 19 21.77 cM
• Gene Summary: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.