Ddr1 (BC065998) Mouse Untagged Clone

CAT#: MC220686

Ddr1 (untagged) - Mouse discoidin domain receptor family, member 1 (cDNA clone MGC:90037 IMAGE:5686085), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ddr1
• Synonyms: 6030432F18, CD167a, PTK3A
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC065998
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGGACAGGGACCCTCTCATCTCTACTGCTGCTGCTACTCTTGGTGACAATTGGAGATGCTGACATGA
  AGGGACATTTTGACCCTGCCAAGTGCCGCTATGCCCTGGGCATGCAGGACCGCACCATTCCTGACAGCGA
  TATCTCTGTGTCCAGCTCCTGGTCGGACTCTACCGCTGCCCGCCACAGCAGGCTGGAAAGCAGTGATGGA
  GATGGGGCTTGGTGCCCTGCAGGGCCTGTGTTCCCCAAAGAAGAGGAGTACTTGCAGGTGGACCTTCGTA
  GGCTACACCTGGTGGCTCTGGTGGGCACCCAGGGCCGCCATGCTGGGGGTCTGGGCAAAGAGTTCTCCCG
  AAGCTATCGGTTGCGTTACTCCCGAGATGGCCGCCGCTGGATGGACTGGAAGGACCGCTGGGGACAGGAG
  GTGATTTCGGGTAACGAGGATCCCGGGGGAGTAGTGCTGAAGGACCTTGGGCCCCCCATGGTGGCCCGGC
  TGGTCCGCTTCTACCCCAGGGCTGACCGGGTCATGAGTGTCTGTCTTCGGGTGGAGCTCTATGGCTGCCT
  CTGGCGGGATGGACTCCTGTCATATACAGCCCCCGTGGGGCAGACCATGCAGTTATCTGAGGTGATGGTA
  CATCTCAATGATTCCACTTACGATGGATATACTGCTGGAGGGCTGCAGTATGGCGGTCTGGGCCAGCTGG
  CAGATGGCGTGGTGGGCCTGGATGATTTCAGGCAGAGCCAGGAGCTGCGGGGCTGGCCAGGCTATGACTA
  TGTGGGATGGAGCAATCAGAGCTTCCCCACGGGCTACGTGGAGATGGAGTTTGAGTTTGATCGGTTGAGG
  ACCTTCCAGACCATGCAGGTCCACTGTAACAACATGCACACTCTGGGAGCCCGCCTACCAGGCGGGGTGG
  AATGCCGGTTTAAAAGGGGTCCCGCCATGGCCTGGGAAGGAGAGCCTGTCCGCCATGCTCTGGGAGGCAG
  CCTTGGAGACCCCAGAGCCCGGGCCATCTCAGTGCCCCTGGGTGGCCACGTGGGCCGCTTTCTGCAGTGC
  AGATTCCTCTTTGCAGGTCCTTGGTTACTCTTCAGTGAGATCTCTTTCATCTCAGATGTGGTGAACGACT
  CCTCTGACACCTTCCCACCAGCCCCCTGGTGGCCACCTGGCCCGCCTCCCACCAACTTCAGCAGCTTGGA
  GCTGGAGCCCCGGGGTCAACAGCCAGTGGCCAAGGCGGAGGGGAGCCCAACTGCCATCCTCATTGGCTGC
  CTGGTGGCCATCATCCTGCTGCTGCTTCTCATCATCGCGCTGATGCTCTGGAGGCTGCACTGGCGCCGGC
  TGCTCAGCAAGGCTGAGCGCCGCGTGTTGGAGGAGGAGCTGACGGTTCACCTTTCTGTCCCTGGGGACAC
  CATCCTCATCAACAACCGCCCAGGACCCCGAGAGCCACCCCCTTACCAGGAGCCCCGGCCTCGGGGGACT
  CCACCCCATTCTGCACCCTGCGTCCCCAACGGCTCTGCCTGCAGTGGGGACTATATGGAGCCCGAGAAGC
  CGGGTGCCCCGCTTCTACCCCCACCTCCCCAGAACAGCGTCCCCCATTATGCCGAAGCTGACATTGTCAC
  CCTGCAGGGCGTCACTGGGGGCAACACCTACGCTGTGCCTGCACTGCCCCCAGGGGCGGTTGGGGATGGG
  CCCCCCAGAGTGGATTTCCCTCGGTCACGGCTCCGCTTCAAGGAGAAGCTTGGCGAGGGCCAATTTGGGG
  AGGTACACCTGTGTGAAGTAGAGGACCCGGCAGCCCTTTCCCAATGGGAGCCATCCAGGGGAAGCTGGAC
  TCGAAAACCAGAGAAGCCTATGGCACCGCACCCCACCGTCTCCATACTTGCCCATTCCCAAGAGGCAGTG
  TCTCTGCGGGTGGGCTGGGCCTGCCCGAGGAGCAGATACACACACTCCCTTCCGTTTCTTCCTTCCATCT
  GCCAAGTGCCACCCTCCCAGCTGGCCCTGTGGTTGGGATCCTGCCTGACTTCTTCCAGCTTTCTTCTTGT
  CACACACTGGACGCCGCCAGCTGAGAATTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCTGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: BC065998
• Insert Size: 2061 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC065998, AAH65998
• RefSeq Size: 2582 bp
• RefSeq ORF: 2060 bp
• Locus ID: 12305
• Cytogenetics: 17 18.7 cM
• Gene Summary: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing, but also tumor cell invasion. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Phosphorylates PTPN11 (By similarity). Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.[UniProtKB/Swiss-Prot Function]