Ptpn6 (NM_001077705) Mouse Untagged Clone

CAT#: MC219501

Ptpn6 (untagged) - Mouse protein tyrosine phosphatase, non-receptor type 6 (Ptpn6), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ptpn6
• Synonyms: 70Z-SHP; hcp; Hcph; me; Ptp1C; PTPTY-42; SH-PTP1; SHP-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219501 representing NM_001077705
  Red=Cloning site Blue=ORF
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTTGTCCCGCGGGTGGTTTCACCGGGACCTCAGCGGGCCTGATGCAGAGACCCTGCTGAAGGGCCGGG
  GAGTCCCTGGGAGCTTCCTGGCTCGGCCCAGCCGCAAGAACCAGGGTGACTTCTCCCTCTCAGTCAGGGT
  GGATGATCAGGTGACTCATATTCGGATCCAGAACTCAGGGGACTTCTATGACCTGTACGGAGGGGAGAAG
  TTTGCGACGCTGACAGAGCTGGTCGAGTATTACACGCAGCAGCAGGGCATCCTGCAGGACCGAGATGGCA
  CCATCATCCACCTTAAGTACCCACTGAACTGCTCGGACCCCACCAGTGAGAGGTGGTACCACGGCCACAT
  ATCTGGAGGGCAGGCGGAGTCACTGCTGCAGGCCAAGGGCGAGCCCTGGACATTTCTTGTGCGTGAGAGT
  CTCAGCCAACCTGGTGATTTTGTGCTCTCTGTGCTCAATGACCAGCCCAAGGCTGGCCCAGGTTCCCCGC
  TCAGGGTCACTCATATCAAGGTTATGTGTGAGGGTGGACGCTATACTGTGGGTGGCTCAGAGACGTTTGA
  CAGCCTCACAGACCTGGTGGAGCACTTCAAGAAGACAGGGATTGAGGAGGCCTCGGGTGCCTTTGTCTAC
  CTGCGGCAGCCTTACTACGCTACTCGGGTAAACGCAGCTGACATTGAGAATCGGGTCTTGGAACTGAACA
  AGAAGCAGGAGTCGGAGGACACAGCCAAGGCTGGCTTCTGGGAGGAGTTTGAGAGTCTACAAAAGCAGGA
  GGTAAAGAATCTACACCAACGTCTGGAAGGGCAGCGGCCAGAGAACAAGAGCAAGAACCGCTACAAGAAC
  ATTCTTCCCTTTGACCACAGCCGAGTGATCCTGCAGGGACGTGACAGTAACATCCCAGGCTCTGACTACA
  TCAATGCCAACTACGTGAAGAACCAGCTGCTAGGTCCAGATGAGAACTCTAAGACCTACATCGCCAGCCA
  GGGCTGTCTGGATGCCACAGTCAATGACTTCTGGCAGATGGCTTGGCAGGAGAACACTCGTGTCATCGTC
  ATGACTACCAGAGAGGTGGAGAAAGGCCGGAACAAATGTGTCCCATACTGGCCCGAGGTGGGCACTCAGC
  GTGTCTATGGTCTCTACTCTGTGACCAACAGTAGGGAGCATGACACAGCAGAATACAAACTGCGAACATT
  ACAGATCTCCCCACTAGACAATGGGGACCTGGTTCGGGAGATATGGCACTACCAGTACCTGAGCTGGCCT
  GACCATGGGGTTCCCAGTGAGCCTGGGGGTGTCCTCAGCTTTCTGGATCAGATCAACCAGCGACAGGAAA
  GTTTGCCTCATGCAGGGCCCATCATTGTGCATTGCAGCGCTGGCATCGGCCGCACGGGCACCATCATCGT
  CATTGATATGCTTATGGAAAGCATCTCCACCAAGGGGCTAGACTGTGACATTGATATCCAGAAGACCATC
  CAGATGGTACGAGCACAGCGCTCCGGCATGGTGCAGACCGAGGCCCAGTACAAGTTTATTTACGTGGCCA
  TTGCCCAGTTCATCGAAACGACCAAGAAGAAACTGGAGATCATACAATCCCAGAAGGGCCAGGAGTCGGA
  GTATGGGAATATCACGTACCCTCCCGCTGTGAGGAGTGCCCACGCCAAAGCCTCGCGTACTTCCTCCAAG
  CACAAGGAGGAGGTGTACGAAAACGTGCATAGCAAGAGCAAGAAGGAAGAGAAAGTAAAGAAGCAGCGGT
  CGGCAGACAAGGAGAAGAACAAAGGTTCTCTCAAGAGGAAGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001077705
• Insert Size: 1794 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001077705.1, NP_001071173.1
• RefSeq Size: 2222 bp
• RefSeq ORF: 1794 bp
• Locus ID: 15170
• UniProt ID: P29351
• Cytogenetics: 6 59.17 cM
• Gene Summary: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (b).