Senp2 (NM_029457) Mouse Untagged Clone

CAT#: MC219434

Senp2 (untagged) - Mouse SUMO/sentrin specific peptidase 2 (Senp2), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Senp2
• Synonyms: 2310007L05Rik; 4930538C18Rik; AI646780; AW554757; mKIAA1331; Smt3ip2; SuPr-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219434 representing NM_029457
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTACAGATGGCTGGCTAAGGTTCTCGGCACCATTCTTCGCTTGTGTGAGCGGCCCGCGCCCGGGGCCC
  GCGCCCTACTCAAGAGGCGGCGCTCCAGCAGCACTCTGTTTTCTACTGCAGTGGACACTGATGAGATCCC
  AGCCAAAAGGCCAAGATTAGATTGCTTTATTCACCAAGTGAAGAACAGTCTCTACAATGCTGCCAGTTTA
  TTTGGATTCCCGTTCCAGCTGACCACAAAACCCATGGTGTCTTCTGCTTGTAATGGAACACGGAATGTGG
  CCCCTTCTGGAGAGGTCTTTTCGAACTCTTCATCTTGTGAGCTGATGAGTTCTGGATCCTGCAGCAGCAT
  GCTGAAACTGGGTAATAAATCTCCTAATGGAATAAGCGACTATCCAAAGATCAGAGTGACAGTGACCCGC
  GATCAGCCACGGAGAGTCCTGCCCTCCTTTGGTTTTACGCTGAAATCGGAAGGCTATAATAGAAGGCCAA
  GTGGTCGTCGCCATAGCAAAAGCAATCCAGAGAGTTCCTTAACATGGAAGCCTCAGGAGCAAGGTGTGAC
  AGAGATGATTTCTGAAGAGGGTGGCAAGGGTGTGAGGCGTCCCCACTGCACCGTGGAGGAGGGTGTCCAA
  AAGGATGAAAGAGAAAAGTATCGAAAGTTATTGGAGCGACTTAAAGAAGGTGCTCATGGAAGCACGTTCC
  CTCCCACGGTTTCACACCACAGTTCTCAGAGAATTCAGATGGACACATTAAAGACCAAAGGCTGGGTGGA
  GGAGCAGAATCATGGCGTCAGAACAACCCATTTTGTTCCAAAACAGTATAGAGTTGTTGAAACAAGAGGA
  CCTCTCTGTTCAATGAGAAGTGAAAAGAGGTATTCAAAAGGGAAAGCTGATACAGAGAAGGTGGTGGGAC
  TCCGATTTGAAAAGGAAGGTACAAGAGGACACCAAATGGAGCCTGATCTGTCAGAAGAAGTGTCTGCCCG
  ACTTCGTCTAGGAAGTGGAAGCAATGGCTTACTCAGAAGGAAAATATCAGTGCTTGAGATAAAGGAAAAG
  AACTTCCCGAGCAAAGAGAAGGACAGAAGAACGGAAGACCTCTTTGAATTTACAGAGGACATGGAAAAGG
  AAATCAGTAATGCCCTGGGCCACGGCCCACCAGATGAGATTTTGAGCAGCGCTTTCAAGTTGCGAATCAC
  CCGCGGAGACATCCAGACCTTAAAGAACTATCATTGGCTCAACGATGAGGTCATTAATTTTTATATGAAT
  CTTTTAGTGGAAAGGAGTAAAAAGCAAGGTTATCCAGCACTTCATGCATTCAGTACATTCTTCTATCCTA
  AGCTAAAGTCTGGAGGTTACCAAGCAGTGAAAAGATGGACCAAAGGGGTAAATCTCTTCGAACAAGAACT
  TGTTCTGGTACCTATTCATCGGAAGGTACATTGGAGCCTGGTGGTGATGGACCTAAGAAAAAAGTGTCTT
  AAATATCTGGATTCTATGGGACAAAAAGGCCACAGGATCTGTGAGATTCTTCTTCAGTATTTACAGGATG
  AAAGCAAGACCAAAAGAAATACAGATCTCAACCTCTTAGAGTGGACCCACTACAGCATGAAGCCACATGA
  GATTCCTCAGCAGTTGAATGGGAGTGACTGTGGAATGTTTACTTGTAAATATGCAGATTATATTTCTAGG
  GACAAACCTATCACATTCACTCAGCACCAGATGCCTCTCTTCCGGAAGAAGATGGTGTGGGAGATCCTTC
  ACCAGCAGTTGCTGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_029457
• Insert Size: 1767 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_029457.3, NP_083733.1
• RefSeq Size: 4499 bp
• RefSeq ORF: 1767 bp
• Locus ID: 75826
• UniProt ID: Q91ZX6
• Cytogenetics: 16 B1
• Gene Summary: Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1 (By similarity). Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620). Isoform 3 activates transcription.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.