Gnl3l (NM_001168600) Mouse Untagged Clone

CAT#: MC219229

Gnl3l (untagged) - Mouse guanine nucleotide binding protein-like 3 (nucleolar)-like (Gnl3l), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Gnl3l
• Synonyms: BC020354
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219229 representing NM_001168600
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATGAAGATTAGACACAAAAACAAAAAACCAGGTAAAGGTTCCAAAGGCTGTAAGAAGCCTGCAAGGC
  AAAATGGGAAGAAAGTAACCTCCAGACCATCATCTGCTCCCCAGATTGTTCATGGCAATGACCATGCCAG
  TCGCGAGGCCGAATTAAAGAAGAAAAGGGTCGAGGAGATGAGGGAGAAGCAGCAAGTTGCCCGGGAGCAA
  GAGAGACAGAGACACAGGACCATGGAGAGCTATTGTCAGGATGTCCTGAAACGTCAGCAGGAATTTGAAC
  AAAAGGAGGAAGTTTTGCAGGAATTAAACATGTTTCCTCAGTTGGATGATGAGGCCACAAGGAAGGCCTA
  TTACAAGGAATTCCGGAAGGTGGTAGAGTACTCTGATGTGATTCTGGAAGTCCTAGATGCCAGAGACCCA
  TTGGGCTGCCGCTGTTTCCAGATGGAGGAGACTGTCCTTCGTGCAGAAGGCAACAAGAAGCTGGTCTTGG
  TCTTAAATAAGATAGATCTCGTTCCCAAGGAGATTGTGGAAAAGTGGCTGGAATACCTTCTCAATGAACT
  GCCAACTGTGGCTTTCAAGGCCAGCACCCAGCATCATCAGGTCAAAAACTTGACTCGTTGTAAAGTTCCA
  GTGGACCAGGCCTCTGAGTCGCTTTTGAAAAGCAGAGCCTGCTTTGGAGCCGAAAATCTCATGAGGGTCC
  TGGGGAACTATTGTCGCCTGGGGGAAGTGCGTGGCCACATTCGTGTGGGTGTTGTAGGCCTTCCCAATGT
  GGGGAAGAGCAGTCTGATCAATAGCCTGAAGCGCAGCCGTGCTTGTAGTGTGGGAGCTGTTCCTGGTGTC
  ACAAAATTCATGCAGGAGGTCTACCTAGACAAGTTTATCAGGCTTCTGGATGCACCAGGCATTGTCCCAG
  GACCCAATTCAGAGGTGGGCACCATCCTGCGTAATTGCATCCATGTGCAGAAGCTGGCAGACCCTGTGAC
  CCCGGTGGAGACCATCCTTCAGCGCTGCAACCTGGAGGAGATTTCCAGCTACTATGGTGTATCTGGATTC
  CAGACGACTGAGCACTTTCTGACTGCAGTGGCCCATCGCTTGGGAAAGAAGAAGAAGGGAGGTGTATATA
  GTCAGGAACAGGCTGCCAAAGCTGTGCTGGCTGACTGGGTGAGTGGGAAGATCAGCTTCTATACACTACC
  ACCGCCCACTCACACTCTGCCCACCCATCTCAGTGCTGAGATTGTTAAGGAGATGACTGAGGTCTTTGAT
  ATAGAAGATACTGAGCACGCCAATGAAGACACCATGGAATGCTTAGCTGTGGGAGAATCCGATGAGCTGT
  TGGGTGACATGGACCCACAAGAAATGGAGGTCAGGTGGCTCCATTCTCCACTGGTGAAAATAGCAGATGC
  TATTGAAAATAGAAGCACCGTGTATAAGATTGGAAATCTCACTGGGTATTGTACCAAACCAAACCGTAAT
  CAGATGGGGTGGCCTAAACGCAATGTGGACCACCATTGCCCCCAAAATAACCGTGTAGTAGAGGTCAGTT
  CTGTGGACCGCCGCCCGATGTTGCAGAGGATCCTGGAGACAGACCCACTTCAGCAAGGCCAGGCTCTGGC
  ATCTGCCTTGAAGAATAAGAAAAAATTGCAGAAGCGTTCAGATAAAATCGCCACTAAGTTGTCTGACTCC
  ATGATGTCCATGCTTGACCTCTCTGGCAACTCCGATGACTGTGCAGGTGACTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001168600
• Insert Size: 1734 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001168600.1, NP_001162071.1
• RefSeq Size: 4844 bp
• RefSeq ORF: 1734 bp
• Locus ID: 237107
• UniProt ID: Q6PGG6
• Cytogenetics: X F3
• Gene Summary: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.