Peli2 (NM_033602) Mouse Untagged Clone

CAT#: MC211991

Peli2 (untagged) - Mouse pellino 2 (Peli2), (10ug)


  "NM_033602" in other vectors (4)

Reconstitution Protocol

USD 457.00

In Stock*

Size
    • 10 ug

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Frequently bought together (3)
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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Peli2
Synonyms AW047589; BB129927
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC211991 representing NM_033602
Red=Cloning site Blue=ORF

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGTTTTCCCCGGGCCAGGAGGAACCCAGCGCCCCCAACAAGGAGCCGGTGAAATACGGGGAGCTGGTGG
TCCTGGGGTACAATGGTGCTTTACCTAATGGTGACAGGGGCAGGAGGAAAAGCAGATTTGCCCTCTATAA
GCGGACCTACGCCAGTGGTGTCAAACCCAGCACAATCCACATGGTCTCCACACCACAGGCGTCCAAGGCC
ATCAGCTCCAGAGGACATCACAGCATATCGTACACGTTGTCACGGAGCCAGACGGTAGTGGTGGAGTACA
CACACGATAAAGACACAGACATGTTTCAGGTGGGCAGGTCAACAGAAAGCCCCATTGACTTCGTGGTCAC
AGACACGGTTTCCGGCGGTCAGAACGAAGATGCCCAGATCACACAGAGCACCATCTCTAGGTTCGCATGC
AGGATCGTGTGTGACAGGAACGAGCCATACACAGCACGCATATTCGCGGCAGGATTCGATTCTTCCAAAA
ATATCTTTCTTGGAGAGAAAGCAGCAAAATGGAAAAACCCTGATGGACACATGGATGGACTCACTACCAA
CGGTGTCCTGGTGATGCACCCGCAAGGAGGCTTCACCGAGGAATCCCAGCCTGGAGTCTGGAGAGAGATC
TCTGTCTGTGGGGATGTATACACCTTGCGAGAGACCAGGTCGGCCCAGCAGAGGGGAAAGCTGGTGGAAA
GTGAGACCAACGTCCTGCAAGACGGCTCCCTCATTGACCTGTGTGGGGCCACTCTCCTCTGGAGAACCGC
AGATGGCCTTTTTCACGCTCCTACTCAGAAGCACATAGAAGCCCTCCGGCAGGAGATCAATGCAGCCCGA
CCCCAGTGCCCCGTGGGCCTTAACACCCTGGCCTTCCCCAGCATCAACCGGAAGGAAGTGGTGGAAGAGA
AGCAGCCCTGGGCATACCTGAGCTGCGGCCATGTGCACGGCTACCACAGCTGGGGCCATCGGAGCGACAC
GGAAGCCAACGAGAGGGAGTGTCCCATGTGCAGGACTGTGGGCCCCTACGTCCCTCTCTGGCTGGGCTGT
GAGGCAGGATTTTATGTCGATGCGGGACCCCCAACTCACGCTTTCACCCCCTGCGGGCACGTCTGTTCAG
AGAAGTCTGCCAAGTACTGGTCGCAGATCCCACTGCCCCACGGAACGCACGCGTTTCACGCCGCCTGTCC
GTTCTGCGCCACGCAGCTGGTTGGTGAACAGAACTGCATCAAATTGATTTTCCAAGGTCCAGTGGACTGA


AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
TGGATTACAAGGATGACGACGATAAGGTTTAA
Chromatograms CHROMATOGRAMS
Sequencher program is needed, download here.
Restriction Sites SgfI-RsrII     
ACCN NM_033602
Insert Size 1260 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_033602.2, NP_291080.2
RefSeq Size 5849 bp
RefSeq ORF 1260 bp
Locus ID 93834
UniProt ID Q8BST6
Cytogenetics 14 24.6 cM
Gene Summary E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.[UniProtKB/Swiss-Prot Function]

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