Fcmr (NM_026976) Mouse Untagged Clone

CAT#: MC210865

Faim3 (untagged) - Mouse Fas apoptotic inhibitory molecule 3 (Faim3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fcmr
• Synonyms: 1810037B05Rik; Faim3; FcmuR; Toso
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC210865 representing NM_026976
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACTTTTGGCTTTGGTTACTTTACTTCCTGCCAGTGTCTGGGGCCCTGAGAGTCCTCCCAGAAGTAC
  AGCTGAATGTAGAGTGGGGTGGATCCATTATCATCGAATGCCCACTCCCTCAACTACACGTAAGGATGTA
  TCTGTGTCGGCAGATGGCCAAACCTGGGATATGCTCCACTGTGGTGTCCAACACCTTTGTCAAGAAGGAA
  TATGAAAGGCGAGTCACCCTGACGCCATGCTTGGATAAGAAGCTATTCCTAGTGGAGATGACACAGCTGA
  CGGAAAATGACGATGGAATCTATGCCTGTGGTGTGGGCATGAAGACAGACAAAGGCAAGACCCAGAAAAT
  CACCCTGAATGTCCATAATGAATACCCAGAACCATTCTGGGAAGATGAATGGACCTCTGAGCGGCCAAGA
  TGGTTGCACAGATTTCTGCAGCACCAGATGCCCTGGCTCCACGGGAGTGAACATCCCAGCTCTTCTGGAG
  TCATAGCCAAAGTTACCACGCCAACTCCAAAGACTGAGGCCCCTCCGGTTCACCAGCCCTCCAGCATCAC
  TTCAGTAACCCAACATCCCAGAGTTTACAGAGCATTTTCTGTGTCAGCTACCAAGTCCCCAGCGCTCCTG
  CCAGCAACCACAGCCTCAAAGACTTCCACTCAGCAAGCAATCAGGCCCCTAGAGGCCAGCTACAGCCACC
  ACACCAGACTTCATGAGCAAAGGACACGCCACCATGGCCCACACTATGGGAGAGAAGACCGAGGGCTTCA
  CATCCCCATCCCAGAATTTCACATCCTGATTCCGACCTTCCTGGGCTTTCTCTTGCTGGTTCTTTTGGGA
  CTGGTGGTAAAAAGAGCCATTCAAAGGAGGAGAGCCTCCTCCAGACGTGCGGGCCGACTAGCGATGAGGA
  GGCGAGGCCGGGGGGCTTCCCGCCCGTTCCCCACACAGCGCCGGGATGCCTCGCAGAGGCCGCGCTCGCA
  GAACAACGTCTACAGCGCCTGCCCCCGGCGCGCACGGGGACCAGACAGCTTGGGTCCAGCGGAGGCTCCG
  CTCCTCAACGCCCCAGCCTCAGCGTCCCCCGCTTCTCCGCAGGTACTTGAAGCTCCTTGGCCCCACACCC
  CATCTCTGAAGATGAGCTGTGAATACGTGAGCTTGGGCTACCAGCCTGCTGTCAACCTGGAAGACCCTGA
  TTCAGATGATTACATCAATATTCCTGACCCATCTCATCTCCCTAGCTATGCCCCAGGGCCCAGATCTTCA
  TGCCAATGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_026976
• Insert Size: 1269 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_026976.2, NP_081252.1
• RefSeq Size: 1491 bp
• RefSeq ORF: 1269 bp
• Locus ID: 69169
• UniProt ID: A1KXC4
• Cytogenetics: 1 E4
• Gene Summary: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation (By similarity).[UniProtKB/Swiss-Prot Function]