Pak1ip1 (NM_026550) Mouse Untagged Clone

CAT#: MC210685

Pak1ip1 (untagged) - Mouse PAK1 interacting protein 1 (Pak1ip1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Pak1ip1
• Synonyms: 5830431I15Rik; 5930415H02Rik; AA419825; AI314040; AW556169; Gdpd1; PIP1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC210685 representing NM_026550
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCTGGTCGCCGGCAGCTACGAGCAGGTCCTGTTTGGGTTCACGGTACAGCGCGGGCCCGCGAAGA
  GTGGCCATCAGGAGACATGGACTCCTGTGGCTGATTTCACTCACCACTCGCACACTGCCTCCCTGTCGGT
  GCTGGCCTCCAACAGTCGCTATGTAGTCTCTGGCAGCAAAGATGAGACGATTCACATTTATGACATGAAA
  AGGAAGGTGGAGCATGGGGCTCTGGTGCATCACGCTGGCACAGTAACTTGCCTGAAATTCCATGGCAACC
  AGCACTTAATCAGTGGGGCAGAAGACGGCCACATCTGCATCTGGGATGTGAAGAGATGGAAGTGCCTGAA
  GACCTTTAAAGCTCACAGGGGACATGTCACTTTCCTTTCTATCCACCCGTCTGGCAAGTTGGCTCTGTCT
  GTTGGCACCGATAAAACATTAAGAACATGGAATCTTATAGAGGGAAGATCAGCTTTCATAAAAAATATAA
  AGGAAAATGCTCACATAGTGGAGTGGTCCCCAAGTGGAGGGAAGTACATAGTTGTTGTGCAGAATAAAGT
  GGATGTCTATCGGCTGGGCACGGCGTCTGTGAGCGGCACCATCACAAACGGAAAGAGGATCTCTTCTGTT
  ACCTTTCTCTCAGACTCTGTCCTTGCAGTGGCTGGAGATGAAGAAGTTGTGAGGATTTTTGACTGTGATT
  CCCTAGAGTGCCTCTGTGAATTCAGAGCTCATGAGAACAGGGTAAAAGACATGGTCAGTTTTGAAGTCCC
  AGACCATCACGTTCTTGTCACAGCATCAAATGATGGCTTCATCAAAATGTGGACGCTTCCACAGGATAAG
  AAAGTTCCTCCATCTTTGCTGTGTGAGGCCAAAACTGGTGCCAGGCTGACATGTCTTACTGTGTGGTTAG
  ACAGAGCAGCAAATGGAATGGCGAGCCTTCCTCCAGCAGCAGAGCCCTGCCCTGACCAACCTAAGACAAT
  CGAAAAGGAATCTGGTGACACAGTTCAGGAAGAAACATCAGAACCTAACTCGGAGAAATCTGATGTAAGT
  GGTGACAGCAAGCAGCCAACAAAAGGAAATAGCCCAGTGACAGCCAAGAAGAGGAAAATGGCAACCATGT
  CGGAAAAGAAGAGAAAGAAGAAAATGTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_026550
• Insert Size: 1149 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_026550.3, NP_080826.2
• RefSeq Size: 1753 bp
• RefSeq ORF: 1149 bp
• Locus ID: 68083
• UniProt ID: Q9DCE5
• Cytogenetics: 13 A3.3
• Gene Summary: Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly.[UniProtKB/Swiss-Prot Function]