Ptprr (NM_001161840) Mouse Untagged Clone

CAT#: MC209265

Ptprr (untagged) - Mouse protein tyrosine phosphatase, receptor type, R (Ptprr), transcript variant 5, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ptprr
• Synonyms: Gmcp1; mPTP213; PTP-SL; PTPBR7; RPTPRR
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC209265 representing NM_001161840
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATTATTTACAGGTTAAAAGAAAGGCTTCAGCTTTCCTTAAGACAAGATAAAGAGAAAAACCAGGAGA
  TCCACCTATCACCCATTGCACGGCAGCAAGCACAATCGGAGGCCAAGACGACCCACAGCATGGTCCAGCC
  CGATCAGGCGCCAAAGGTGCTGAACGTGGTTGTGGACCCTCAAGGCCAATGCACTCCTGAGATTCGAAAC
  AGCACCTCCACCTCTGTCTGCCCTTCTCCCTTCAGAATGAAGCCCATAGGACTCCAGGAGCGACGAGGTT
  CCAATGTATCTCTTACGCTGGACATGAGTAGCCTGGGCAGTGTGGAACCCTTTGTGGCCGTCTCAACCCC
  CCGGGAGAAGGTAGCCATGGAATACCTGCAGTCAGCCAGCCGAGTTCTCACACGGTCACAGCTGAGGGAC
  GTCGTGGCAAGTTCCCACCTACTTCAAAGTGAATTCATGGAAATACCAATGAATTTTGTGGATCCCAAAG
  AAATTGATATTCCACGTCACGGAACTAAAAATCGTTATAAGACCATTTTGCCAAATCCCCTCAGCAGAGT
  GTGCTTAAGACCAAAAAATATAACCGATTCCTTGAGTACTTACATAAATGCTAACTATATTCGGGGCTAC
  AGTGGTAAGGAGAAAGCCTTCATTGCCACCCAGGGCCCCATGATCAACACTGTGAATGACTTCTGGCAGA
  TGGTGTGGCAAGAAGACAGTCCCGTGATTGTGATGATCACGAAACTCAAAGAGAAAAATGAGAAATGTGT
  GCTCTACTGGCCAGAAAAGAGAGGGATTTACGGCAAGGTTGAGGTTCTGGTCACCGGTGTGACCGAATGT
  GATAACTACACCATCCGCAACCTCGTCTTAAAGCAAGGAAGTCACACCCAACATGTGAAGCACTACTGGT
  ACACTTCATGGCCGGATCATAAGACTCCAGACAGTGCCCAGCCCCTTCTGCAGCTCATGTTGGATGTGGA
  AGAAGACAGACTGGCCTCTGAAGGCCGAGGGCCTGTGGTTGTCCACTGCAGTGCGGGGATTGGGAGAACT
  GGGTGTTTCATCGCTACATCCATTGGCTGTCAACAATTGAAAGAAGAAGGAGTTGTAGACGCACTAAGTA
  TTGTCTGCCAGCTTCGTGTAGACAGGGGTGGTATGGTCCAAACCAGCGAGCAGTATGAATTTGTGCACCA
  TGCTCTGTGCCTGTTCGAGAGCAGACTTTCACCAGAAACTGTCGAGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001161840
• Insert Size: 1239 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001161840.1, NP_001155312.1
• RefSeq Size: 2700 bp
• RefSeq ORF: 1239 bp
• Locus ID: 19279
• UniProt ID: Q62132
• Cytogenetics: 10 D2
• Gene Summary: Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. Isoform gamma may have a role in patterning and cellular proliferation of skeletal elements in the precartilaginous/cartilaginous skeleton.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a.