Clec4n (NM_020001) Mouse Untagged Clone

CAT#: MC205794

Clec4n (untagged) - Mouse C-type lectin domain family 4, member n (Clec4n), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Clec4n
• Synonyms: Clec6a; Clecsf10; Nkcl
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC023008
  CATTGGCCCGCTCTGTGGCATTTAACTCAAGTGTGTGTGGAAGTTGATTCTGAACTCTGGCCTCTTTGAC AGAAGCCAGGTCCCTGAGTCGTATTTTGGAGACAGATGCAAGAAACCCCTGACCTTCTGAACATACACCT CAACAATGGTGCAGGAAAGACAATCCCAAGGGAAGGGAGTCTGCTGGACCCTGAGACTCTGGTCAGCTGC TGTGATTTCCATGTTACTCTTGAGTACCTGTTTCATTGCGAGCTGTGTGGTGACTTACCAATTTATTATG GACCAGCCCAGTAGAAGACTATATGAACTTCACACATACCATTCCAGTCTCACCTGCTTCAGTGAAGGGA CTATGGTGTCAGAAAAAATGTGGGGATGCTGCCCAAATCACTGGAAGTCATTTGGCTCCAGCTGCTACCT CATTTCTACCAAGGAGAACTTCTGGAGCACCAGTGAGCAGAACTGTGTTCAGATGGGGGCTCATCTGGTG GTGATCAATACTGAAGCGGAGCAGAATTTCATCACCCAGCAGCTGAATGAGTCACTTTCTTACTTCCTGG GTCTTTCGGATCCACAAGGTAATGGCAAATGGCAATGGATCGATGATACTCCTTTCAGTCAAAATGTCAG GTTCTGGCACCCCCATGAACCCAATCTTCCAGAAGAGCGGTGTGTTTCAATAGTTTACTGGAATCCTTCG AAATGGGGCTGGAATGATGTTTTCTGTGATAGTAAACACAATTCAATATGTGAAATGAAGAAGATTTACC TATGAGTGCCTGTTATTCATTAATATCTTTAAAGTTCAGACCTACCAAGAAGCCATAACTTCTTGGCCTG TACATCTGACAGAGGCCGTTCTTTTCCTAGCCACTATTCTTTACTCAAACAGAATGAGCCCTTTCTCCTT CTGATGGTTAGAGTTTTGTCAACTTGACACAAACTAGAGTCACCTGGGGAGTAGGATCTTCAGCTAAGGA ATTGCCTCTGTCAGCTTGACCAGTCAGCATGTCTGGGGGCATTTTCTTGATTAATGATTGTTGTAAGAGG GTCCAGGTGGTAAGCAAAGGTGTTAAACCCATGAAGAGCAAGCCAGGGAGCATCATCCATCCATCTCTGC CCTCAGGTTTCTGCCCCAGGGTCTTGCCCTGGTTTCTTTCTATGAACTGCTGTTACTTGAAAGTATAAGA TGAATAAACAATTTCATCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_020001
• Insert Size: 630 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC023008, AAH23008
• RefSeq Size: 1254 bp
• RefSeq ORF: 630 bp
• Locus ID: 56620
• UniProt ID: Q9JKF4
• Cytogenetics: 6 58.3 cM
• Gene Summary: Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).