Dis3l (NM_172519) Mouse Untagged Clone

CAT#: MC205098

Dis3l (untagged) - Mouse DIS3 mitotic control homolog (S. cerevisiae)-like (Dis3l), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Dis3l
• Synonyms: AV340375
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC056939
  GCCGCCTGCCGCCCGCCGCCCGCCGCTTCCCGGCCACAGTGCCGGGCGACGCCGCCAGCATGCTGCAGAA GCGGGAGAAGGTGCTGCTGCTGAGGACCTTCCAGGGTCGGACGCTGCGGATCGTGCGTGAACACTACCTG CGGCCCAGCGTGCCTTGCAACAGCCCGCTGTGCCCGCAGCCTGCCGCCTGCCGCAACGATGGGAAGCTCC TGGCTGCCGAAGTCACTCATTACGTGATCCCAGACTGGAAAGTTGTCCAGGATTACCTCGAGGTTCTGGA GTTCCCGGAGTTGAAGGGAGTTATTTTCATGCAAACGGCCTGTCAAGCTGTGCAGCACCAGAGAGGCCGG AGACAGTATAACAAACTGCGAAACCTCCTGAAGGATGCTCGCCATGACTGCGTTCTCTTTGCTAACGAGT TCCAGCAGCACTGTTACCTCCCCCGGGAAAAGGGGGAAGCCATGGAGAAGTGGCAGACCAGGAGCATATA CAACTCAGCGGTTTGGTACTATCACCACTGTGAGGACAGGATGCCCATCGTTATGGTGACAGAAGATGAA GAGGCCATTCAGAAGTATGGAAGTGAAACAGAAGGCGTATTTGTCATTTCTTTCAAGAATTACCTGGACA ACTTCTGGCCAGATTTGAAGGCTGCCCACGATCTCTGTGACTCCATCCTTCAGTCTCGCCGGGAAAGGGA GACTGAGAGTCAGGAAACCCATGGGAAAGAGTACCCAGAACATCTTCCCCTAGAAGTACTGGAAGCGGGC ATCAAATCTGGACGCTACATCCAGGGAATTCTGAATGTCAACAAGCACAGAGCTCAGATTGAAGCTTTCG TTCGCCTACACGGAGCCAGCAGTAAGGACTCAGGCTTGGTCAGCGACATCCTCATCCATGGCTCGAAGGC TCGGAACCGCTCCATCCATGGAGACGTCGTGGTGGTGGAGATGCTCCCCAAAAGTGAGTGGAAAGGGAGA ACAGCCGCCCTGGGTGAGAACGACAGTGATGACAAGGCCTCGGGCGAGTCCCCGAGTGAGCCCATGCCCA CAGGTCGAGTGGTAGGCATCCTTCAGAAGAACTGGCGAGATTATGTGGTGACATTTCCATCCAAAGAAGA GGTCCAGTCTCAGGGCAAAAATGCTCAGAAGATCCTGGTTACGCCGTGGGATTACAGAATCCCTAAGATC CGCATCAGCACCCAGCAAGCAGAAGCCCTCCAGGATTTCAGGGTGGTTGTGCGCATTGACTCCTGGGAGG CAACATCAGTGTATCCAAATGGACATTTTGTGCGTGTCTTAGGGAGAATCGGTGATCTGGAAGGGGAGAT TGCAACCATCCTGGTAGAGAACAGTATCTCTGTGGTCCCCTTCTCAGAAGCCCAGATGTGTGAGATGCCA GTGAACACACCAGAAAACCCTTGGAAAGTGAGTCCCAAAGAAGAGCAAGAGCGGAAGGACCTGAGGACCA CCCACCTCGTGTTCAGCATCGACCCCAAAGGTTGTGAAGATGTGGATGACACACTCTCAGTCAGAACCTT GAATAACGGCAACCTGGAGCTGGGGGTCCACATCGCTGACGTCACACACTTTGTGGCCCCTAACTCTTAC ATCGATGTTGAAGCTAGAACGAGGGCCACCACTTACTACCTAGCGGACCGTCGCTATGACATGCTGCCTT CCATCCTCAGCGCAGACCTCTGCTCCCTCCTGGGAGGCGTTGACCGGTATGCTGTGTCAGTCATGTGGGA ATTAGATAAAACCTCTTATGAAATTAAGAAGGTGTGGTACGGCAGAACCATTATCCGATCAGCTTACAAA CTGTTCTACGAGGCGGCCCAGGAACTACTGGACGGAAACTTCAGCATTGTTGATGATATTCCAGAACTTA AAGCCTTGGACAAGCAGAGCCAACAGGCCAAACTAGAGGAGTTAGTGTGGGCAATTGGAAAGTTGACAGA CATAGCTCGCCACATCCGAGCAAAGAGAGACCGCTGTGGAGCCTTGGAGCTGGAAGGGGTAGAGGTTCGA GTCCAGCTGGATGACAAGAAGAACATCCGTGACCTCATCCCCAAGCAGCCCCTGGAGGTTCACGAGACGG TGGCTGAGTGCATGATCCTAGCCAACCACTGGGTGGCCAAGAAGATCTGGGAGAGCTTCCCCCACCAGGC TCTGCTGCGCCAGCACCCTCCACCACACCAGGAGTTTTTCTCAGAGCTCCGGGAATGTGCTAAAGCAAAA GGCTTCTTCATAGACACACGGTCCAATAAAACCCTGGCTGACTCTCTGGATAGTGCAAATGACCCCAAGG ACCCCCTGGTAAACAAGCTGCTGCGCTCCATGGCCACCCAGGCCATGTCCAACGCGCTCTACTTCTCTAC GGGATCCTGCGCAGAGGAGGAGTTCCATCATTACGGGCTGGCCTTAGATAAATACACCCACTTTACCTCT CCAATAAGAAGATACTCAGATATTGTAGTACATCGGCTATTAATGGCAGCCATTTCAAAAGACAAGAAAA TGGAGATTAAAGAAAATTTGTTCAGCAACAAAAATCTTGAGGAATTATGCAGACACATTAACAACAGAAA CCGAGCGGCACAGCGGTCTCAGAAGCAGTCCACCGAGCTCTTCCAGTGCATGTACTTTAAAGACCGAGAT GCAGAAACTGAGGAGCGCTGCATAGCTGATGGAGTTATTTATTCCATTAGAACAAATGGTGTACTTGTAT TTATACCAAGGTTTGGGATTAAAGGTGCTGCTTATCTGAAGAATAAAGATAGCTTAGTGATCTCCTGTGG CCCAGAGGGCAGCTCTGAATGGAAGCCAGGATCCCTACAAAGATCTCAAAACAAGATCATCTCTACCACA GCTGGAGGGCAGTCTGTTACATTTCATCTATTTGACCATGTGACGGTAAGAATTTCTGTCCAGGCCTCGC GCTGCCACTCTGATACAATCAGGCTTGAAATAGTAAGCAACAAGCCATACATGATCCCAAACACAGAACT CTGTCACCAGAGCTCCCTGCTGAAGAGTGAGTTAGTGAAGGAAGTAACCCGATCTGTGGAGGAAGCGCAG CTTGCACAAGAAGTCAAAGGCAAGGTGATTCAGGAAGAGCATCAAGAATACTGCCAGACAAAGGGAAGAA GTCTGTACACACTTCTGGAGGAGATAAGGGACCTAGCTCTTCTGGATGTCTCTGACAGTTGTGCAATGTG AAATACTTCCATGTCATTAAAGACCTTTGTCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_172519
• Insert Size: 2913 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC056939, AAH56939
• RefSeq Size: 3289 bp
• RefSeq ORF: 2913 bp
• Locus ID: 213550
• UniProt ID: Q8C0S1
• Cytogenetics: 9 C
• Gene Summary: Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform.