Cd6 (NM_009852) Mouse Untagged Clone

CAT#: MC204266

Cd6 (untagged) - Mouse CD6 antigen (Cd6), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cd6
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC014294
  CCACGCGTCCGGCAGAAGGTAGAGGCGTGAGACACTCACAGGCTGGGCCTGTGTGTAGGAGAGAGAGTGC GCAGCACACAGGGCACTGAGAACAAGAACAGAAAGGGCACCACGGGTGAGACAAGCCATCGGTGGCACAA CCGTCTCCCGGAACCAGGATGGCACTTCCTATGGGCAGGCGTGAGTAGCAGTGGAGACAGCACCAGACAT GTGGCTCTTCCTTGGGATCGCTGGATTGCTGACAGCAGTTCTCTCAGGTCTCCCATCTCCAGCCCCCTCT GGCCAGCACAAAAATGGCACCATCCCGAACATGACCTTGGACCTAGAGGAGCGGCTGGGGATTCGCCTGG TGAACGGGAGCAGTCGCTGCAGCGGATCTGTGAAGGTTCTACTGGAGTCCTGGGAGCCTGTGTGTGCGGC ACACTGGAACAGGGCTGCTACGGAGGCTGTGTGCAAAGCGCTGAACTGTGGTGATTCGGGAAAGGTTACC TACCTGATGCCACCCACCTCTGAGCTTCCACCAGGAGCCACTTCTGGGAACACAAGCAGCGCCGGGAATA CGACGTGGGCGCGGGCACCAACTGAGAGATGCAGGGGAGCCAATTGGCAGTTCTGCAAGGTGCAGGACCA GGAGTGTAGCAGCGACAGGCGGCTGGTGTGGGTCACCTGTGCAGAGAACCAAGCGGTGCGGTTAGTGGAT GGTAGCAGCCGCTGTGCTGGCCGAGTGGAGATGCTGGAGCATGGTGAATGGGGTACCGTGTGCGACGACA CGTGGGACCTGCAGGATGCACACGTAGTGTGTAAGCAACTGAAGTGCGGCTGGGCAGTGAAGGCGCTGGC CGGCTTGCACTTCACCCCAGGCCAAGGACCCATCCACCGCGATCAGGTGAACTGCTCTGGGACTGAGGCT TACCTGTGGGACTGCCCGGGACGGCCAGGAGACCAGTACTGTGGTCACAAGGAGGACGCAGGAGTGGTGT GCTCAGAGCACCAATCCTGGCGCCTGACTGGAGGCATTGACTCCTGCGAAGGGCAAGTGGAAGTGTACTT CCGGGGTGTCTGGAGCACGGTGTGTGACAGCGAGTGGTACCCATCTGAGGCCAAAGTGCTCTGTCGGTCC TTGGGTTGCGGATCAGCAGTGGCTCGGCCCAGGGGGCTGCCACACTCCCTGGACGGTAGAATGTACTACT CCTGCAAAGGACAGGAGCCCGCCCTCAGCACCTGTTCCTGGCGGTTCAACAACTCCAACCTGTGCAGCCA GTCGCGGGCAGCCAGGGTTGTCTGCTCAGGCTCCCAGAGACATCTCAATCTGTCTACTTCTGAAGTGCCT TCCAGAGTTCCAGTCACGATAGAATCTTCTGTGCCGGTGAGCGTGAAGGATAAGGACTCACAAGGGCTGA CACTTCTCATTCTCTGTATTGTCCTGGGAATTCTCCTCCTCGTCTCCACCATCTTCATAGTTATTCTTCT CTTGAGAGCCAAAGGACAATACGCCCTCCCTGCTTCAGTGAACCACCAGCAACTGTCTACTGCCAACCAA GCAGGGATCAATAACTACCATCCTGTCCCTATCACCATTGCCAAAGAAGCTCCTATGCTGTTCATCCAGC CCCGGGTCCCTGCAGACTCGGACTCCAGTTCTGACTCCGACTATGAGCACTATGACTTCAGCTCCCAGCC GCCTGTGGCCCTGACCACCTTCTACAATTCCCAGCGACACCGGGTCACAGAGGAGGAAGCTCAGCAGAAC AGGTTTCAGATGCCACCCTTGGAGGAAGGACTTGAAGAGCTGCATGTTTCCCACATCCCAGCGGCTGACC CCAGACCCTGTGTGGCAGATGTCCCCTCTCGGGGCTCTCAGTACCACGTGAGGAACAACAGTGATTCCAG CACCTCCTCTGAGGAGGGCTACTGCAATGATCCCAGCAGCAAGCCACCTCCATGGAATTCCCAGGCGTTT TATTCTGAGAAGAGTCCCCTCACAGAGCAGCCCCCCAACTTGGAACTGGCTGGCTCTCCGGCAGTGTTTT CAGGGCCCTCAGCCGATGACAGCTCCAGCACCTCATCCGGAGAGTGGTACCAGAACTTCCAGCCACCACC CCAGCATCCTCCAGCAGAACAGTTTGAATGTCCAGGACCCCCTGGCCCCCAAACAGACTCCATTGATGAG GAGGAGGAGGATTACGATGACATCGGAGCAGCCTAGCCTGGGTCCCTGAGGCTCCTGGGTGGCCCCTCCC TCTGCTCTCTTGTTCTAGCCCCTAGCAGAGGTGGAAGGGTGGGCATTCTCCCAGCCCCTCATCCTCCACC CATTGATTAACCTGCAGGAGCCCGAACAGAAGACAAAGCCAGTGGTGTGAGAGCTGAGTCCTGGGTTGAA CAAACAGGGTCTGGCCACTTCTTGGGAGTGGTGAAGGGGCATGCTGGGTGACCCTGAGGCCTTATCTCAC TCTGTGTCTGGCGCTTTGATCCTAAGCCTCAGGAAGCTGCTGAAGGGGCTGAGTAGCCCACCCACTGCTG AAATACAGGCCCTGGGCCAGGGGCTGCCATTATCACCCAGGAAGTCAGCGATGTCTCAATACAACCTGGG ACCTCAATCAATCAGAGTAGCAGCCGCTTTAGCACGGGCATGGCCTCCCTGGGCACTGTCACCTAAGAGT AACCATGGTGAATACATGCTTGCTTCCAGAGGTCTCTGAGTCCACCACAGGCACTAGCTGGACTCCTTTC TCTATCCCTAGACAACTGAACATTATTCTAATTCCTTGGGCTTTATAAGAGCATCCCTGCCCTGCCTGAG TCAGGGGATCCACAGCCCCATTGGGACAAGAATGCAGGGACCTGTTCTGGAGGGCTAGAGGGCACCAAAA GCTCCGAGTCCCCACAGGTCCCCTTGGGTTGACAGGAACACTTTGGGAGAGTGTGGTTATTGCAGCCAAG ACCTTAAACAGGTCCTCCCCACAGCGTCAGAGAACTGGAGGGTCCCAGCCAGGCTACAGTGGCCTGTCCT GAGTTCCAGAGATTAAACGATTACTGAGTGAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_009852
• Insert Size: 1998 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC014294, AAH14294
• RefSeq Size: 3057 bp
• RefSeq ORF: 1998 bp
• Locus ID: 12511
• UniProt ID: Q61003
• Cytogenetics: 19 7.16 cM
• Gene Summary: Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089). Functions as costimulatory molecule; promotes T-cell activation and proliferation. Contributes to the formation and maturation of the immunological synapse. Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria. LPS binding leads to the activation of signaling cascades and down-stream MAP kinases. Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) represents the longer transcript and encodes the longer protein (isoform 2).