Gadd45a (NM_007836) Mouse Untagged Clone

CAT#: MC203784

Gadd45a (untagged) - Mouse growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Gadd45a
• Synonyms: AA545191; Ddit1; GADD45
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC011141
  GGCAGAGTTCCCCAGCGAGGCTAGGCGAGCAGCCGGCCGGCCGGAGCGGAGAAGGGAGGGTGGGAGCGAG CGCAGAGCCGGCGCCGCGCACTGTGGGGGCCAGGAGCAGCCCGCGCGCCGAGGGAGGGACTCGCACTTGC AATATGACTTTGGAGGAATTCTCGGCTGCAGAGCAGAAGACCGAAAGGATGGACACGGTGGGCGATGCCC TGGAGGAAGTGCTCAGCAAGGCTCGGAGTCAGCGCACCATTACGGTCGGCGTGTACGAGGCTGCCAAGCT GCTCAACGTAGACCCCGATAACGTGGTACTGTGCCTGCTGGCTGCTGACGAAGACGACGACCGGGATGTG GCTCTGCAGATCCATTTCACCCTCATCCGTGCGTTCTGCTGCGAGAACGACATCAACATCCTGCGGGTCA GCAACCCGGGTCGGCTAGCTGAGCTGCTGCTACTGGAGAACGACGCGGGCCCGGCGGAGAGCGGGGGCGC CGCGCAGACCCCGGACCTGCACTGTGTGCTGGTGACGAACCCACATTCATCACAATGGAAGGATCCTGCC TTAAGTCAACTTATTTGTTTTTGCCGGGAAAGTCGCTACATGGATCAGTGGGTGCCCGTGATTAATCTCC CGGAACGGTGATGGCATCCGAATGGAAATAACTGAACCAAATTGCACTGAAGTTTTGAAATACCTTTGTA GTTACTCAAGCAGTCACTCCCCACGCTGATGCAAGGATTACAGAAACTGATGTCAAGGGGCCGAGTTCAA CTGCACGAGGGCTCAGAGATGACTTTGCAGAGGGAGAGAGAGGTGAGCCTGAAGAAGGAAGCTGCGAGAA AAGAGAAATCCAAGGCAAAAGGGACAAAAACTACAAAGCACTGCAAGAAAGAAAACTGCTAATTTAGGAT GGCCAGGTTACTTTCAAATAAGCCAAATATTGCTTTGTTGAAACTTTAAATGTATAGCAATAGTTTGGGT ATTTTTTTTCTTTTTTTTTTTTGGTCTTTATGCCCTCAAATAAAAGGAAAGTAAAAGAGGATTAATCATA TTTTCAAGCCACAGTTTAAATGTATTTTGATGAGATGTTAAATTCTCAGAAGTTTTATTATAAATCTTAC TAAGTTATTTTATGATGTGAAAGGTTATTTATGATAAAGTTTTTGAAGCACATTATCTAAAATAAACTGG TATGGAATAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_007836
• Insert Size: 498 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC011141, AAH11141
• RefSeq Size: 1219 bp
• RefSeq ORF: 498 bp
• Locus ID: 13197
• UniProt ID: P48316
• Cytogenetics: 6 C1
• Gene Summary: Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity.[UniProtKB/Swiss-Prot Function]