Fbxo7 (NM_153195) Mouse Untagged Clone

CAT#: MC202931

Fbxo7 (untagged) - Mouse F-box protein 7 (Fbxo7), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fbxo7
• Synonyms: 2410015K21Rik; A230052G17Rik; AI117679; AW260462; C85118
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC032153 sequence for NM_153195
  CCACGCGTCCGCCCACGCGTCCGTCCGACTCTCGCCATGAAGCTGCGCGTGCGGCTTCAGAAGCGGACCC AGCCGCTCGAGGTGCCGGAGTCGGAGCCAACGCTCGGGCAGCTGCGCGCGCACCTCAGCCAGGTCCTGCT GCCCACGTTGGGGTTCAGTTCTGATACCCGATTTGCAATTACATTGAACAACAAGGATGCCCTCACTGGA GATGAAGAGACCTTGGCTTCATATGGGATTGTTTCTGGGGACTTGATATGTTTGGTTCTTGAAGATGACA TGCCGGCACCTAACTTACCTTCATCTACAGATACAGAGCATTCCTCACTCCAGGATAATGACCAACCTTC TTTGGCTGCCACCCCAAGTCAGACTAACATCCCAGATGAACAAGGGACTGATTCATCCCAAGGACAGGCC ACCCCATTTGATGCCTGGACTGATGACAGTATGGAAGGGCCTAGTCAAAATGTTGAAGCTGAGTCAATTC AGGATGCCATGAGTATGGAAGAGGTTTCTGGTTTCCATCCATTGGAACCAATGCTCTGTAATGAAACAGA GGATGGGCAGGTACCACATTCTCTAGAGACCCTGTACCAGTCAGCTGGCTGCTCCAACATCAGTGATGCC TTGATAGTGCTGGTGCATCTCCTGATGCTCGAGTCAGGCTACATTCCTCAGGGAACTGAAACCAAAGCAG TGACAATGCCTGAGAATTGGAAGTCAAGTGGTGTATACAAACTGCAGTACACACATCCTCTCTGCGAGGG CGGCTTTGCCGTGCTTACCTGTGTGCCTTTGGGAAACTTAATCATTATAAATGCTACAATAAAAGTCAAC GGTGGGATTAAAAACGTGAAGTCAGTGCAGCTGCAGCCAGGATCCTACGTTGCTGCTGGAGTAGAACCAG GGGAAAGCGCAGCCAAAGTGTACAAAGATCTTAAGAAGCTCTCTCGTCTCTTCAAAGACCAGCTGGTGTA CCCTCTTCTGGCTTTCACACGGCAAGTACTGAACCTTCCAGATGTGTTTGGGCTGGTTGTCCTTCCACTG GAGCTGAAACTACGCATCTTCCGACTTTTGGATGTTCATTCTGTCCTGGCCCTGTCTGCAGTCTGTCATG ACCTCCTCATTGCGTCAAATGACCCACTGCTGTGGAGGTGTTTGTATCTGCGGGATTTTCGAGATGGCAC TGTCAGAGGTCCTGACACAGACTGGAAAGAATTGTATAGAAAGAAGCACATACAAAGAAAAGAGGCTCAG AGGATGCGGCATGCAATGTTCCTACCATCAGCCCACCCTATCCCATTTTGTCCCATTCCCGTCTACCCCA GGGCCTACCTTCCCACCTCGCTGCTTCCTCCAGGAATCATTGGTGGTGAATATGATGAGAGGCCGATACT GCCTAGTGTTGGGGACCCAGTCACCTCACTTATCCCAAGGCCCGGGGAGCTTCCTGGTCAGTTCCGTCCA CTCAGACCACGTTTTGACCCTGTTGACCCACTTCCAGGACCTCACTCCCTCTTGCCAGGAAGAGCTATCC CCAACAACAGATTTCCCTTCAGACCCGGCAGGGGTAGGTCAGCTGACAGCCGGCTGCCATTCCTGTGACC AATTTGGAGACTTTATGGAAACTGGATGCTGTTTCCTTGGATGCTGATCTCTGCTGTCGGTTTCTGGTTC TGTGGGCACCAAGGACAAGGTTGCTCAAAGAGGGGTCAGCTTGGGAATAGGTGACTGCTGGTCTCTCCCC TCTGGTTCACCTCTGGGATGGAGATTGTGGTATTGATAATGTTTTGTGTTATATTAGTAAAAGTAAAAAT TGTATGGCAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_153195
• Insert Size: 1572 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC032153, AAH32153
• RefSeq Size: 1846 bp
• RefSeq ORF: 1572 bp
• Locus ID: 69754
• UniProt ID: Q3U7U3
• Cytogenetics: 10 C1
• Gene Summary: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PRKN to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes the longer isoform (1).