Fbxo7 (NM_153195) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR208381L4V

Lenti ORF particles, Fbxo7 (GFP-tagged) - Mouse F-box protein 7 (Fbxo7), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Fbxo7
• Synonyms: 2410015K21Rik; A230052G17Rik; AI117679; AW260462; C85118
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_153195
• ORF Size: 1572 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR208381).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_153195.2
• RefSeq Size: 1886 bp
• RefSeq ORF: 1572 bp
• Locus ID: 69754
• UniProt ID: Q3U7U3
• Cytogenetics: 10 C1
• Gene Summary: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PRKN to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination (By similarity).[UniProtKB/Swiss-Prot Function]