S1pr1 (NM_007901) Mouse Untagged Clone

CAT#: MC202722

S1pr1 (untagged) - Mouse sphingosine-1-phosphate receptor 1 (S1pr1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: S1pr1
• Synonyms: AI849002; Edg1; Lpb1; S; S1; S1p; S1p1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC049094 sequence for NM_007901
  CCCAGCCTCGGCGGGGCGCTCAGAGACTTCGTCTTGCAAAAGTGGTGCGGGCAGCGCAGGCAGGGCTGGC CATTGGAGTGCACCGCTGAGGAGGGAGGGGACCCCAGCTCAGGGAACTTTGCGAGTGAGCTGGTCGCCGT CAGTCGCCGACAGCAGCAAGATGCGGATCGCGCGGTGTAGACCCAGAGTCCTGCGGACGCAGCTTCGTCC GGCTTGAGCGAGGCTGCTGTTTCTCGGAGGCCTCTCCAGCCAAGGAAAAGCTCCATAAAAGAAAAAAGCA TTGGATTGCTCGCTGACCTGGCTTTGCTGTAACTGAAGGCTCACTCAACCTCGCCCTCTAGCGTTTGCCT GGAGAAATACCACCCCAGGCTCCTGGGGACACAATTAGCAGCTATGGTGTCCACTAGCATCCCGGAGGTT AAAGCTCTCCGCAGCTCAGTCTCTGACTATGGGAACTATGATATCATAGTCCGGCATTACAACTACACAG GCAAGTTGAACATCGGGGCGGAGAAGGACCATGGCATTAAACTGACTTCAGTGGTGTTCATTCTCATCTG CTGCTTCATCATCCTAGAGAATATATTTGTCTTGCTAACTATTTGGAAAACCAAGAAGTTCCACCGGCCC ATGTACTATTTCATAGGCAACCTAGCCCTCTCGGACCTATTAGCAGGCGTGGCTTACACAGCTAACCTGC TGTTGTCTGGGGCCACCACTTACAAGCTCACACCTGCCCAGTGGTTTCTGCGGGAAGGGAGTATGTTTGT GGCTCTCTCTGCATCAGTCTTCAGCCTCCTTGCCATCGCCATTGAGCGCTACATCACCATGCTGAAGATG AAACTACACAACGGGAGCAACAGCTCGCGCTCCTTTCTGCTGATCAGCGCCTGCTGGGTCATCTCCCTCA TCCTGGGGGGCCTGCCCATCATGGGCTGGAACTGCATCAGCTCGCTGTCTAGCTGCTCCACCGTGCTCCC GCTCTACCACAAGCACTATATTCTCTTCTGCACCACCGTCTTCACTCTGCTCCTGCTTTCCATCGTCATC CTCTACTGCAGGATCTACTCCTTGGTCAGGACTCGAAGCCGCCGCCTGACCTTCCGCAAGAACATCTCCA AGGCCAGTCGCAGTTCTGAGAAGTCTCTGGCCTTGCTGAAGACGGTGATCATTGTCCTGAGTGTCTTCAT TGCCTGCTGGGCCCCTCTCTTCATCCTACTACTGTTAGATGTGGGCTGCAAGGCGAAGACCTGTGACATC CTGTACAAAGCAGAGTACTTCCTGGTTCTGGCTGTGCTGAACTCAGGTACCAACCCCATCATCTACACTC TGACCAACAAGGAGATGCGCCGGGCCTTCATCCGGATCGTATCTTGTTGCAAATGCCCCAACGGAGACTC TGCTGGCAAATTCAAGAGGCCCATCATCCCAGGCATGGAATTTAGCCGCAGCAAATCAGACAACTCCTCT CACCCCCAGAAGGACGATGGGGACAACCCAGAGACCATTATGTCGTCTGGAAACGTCAATTCTTCTTCCT AAAGCCTGAAGAAGCTGTTGATACTGAGGGAAGCATTCTGACTTGATCACCCACTACCCCAGCATTTCAA AAATGTCTCTCGCTCTCCACTGCTGCAAGGAAGGAGCAACTGGGAGCCTGAGAGAGGGAGGGAAGGGAGA ATGTGCGGCCTGGTGATACCATGATGTAGGTAGGTAGTAATTGTGAACAATGCACTGGGAAGGGTGGAGA TCAGGTCTGGCCTGCAGTGGGTTTCCTGCCCCCCCCTCCCCCGTACCCTGGAGCTTTGATTTTGCACTGA GCCAAAGGTCTAGCATTGTCAAGCTCCCAGAGGGCTCATCTGGTCCCTCCTCAAAGACTAAGGTCCCAAG AGAAAGTGTTGTGATCTCTCACTGTAATGTCAAAGTGAGTATGTGCCCTTTAGCTTGGTTGGGTGGTGTA CATGTCCCCACCCTCCGGTTTCTTCTCACCCTGTCTCCCCTTACCACCCCTTCTTTATATCGTAACTGCC TGACTTTTGTTCATCAGAAGGAGGTTGTGGAGGGGTCTATTTCTTGATTATAGTGAGCAAGCTATTTGCT GGGAAGGCTATTTGCTGAGGCCAAAGTTTCCATGTAAACTGGGTCAAGTTGTTGGGAATTTGGTAGGCCA TCTTTAAGATGAAAATGTGTTCCTTTTTTGTCACATGTTCCTTATTCCCATTACAACCACAATGGTTGTG AATGAAGAGTAACAAAGAATAACGAAGTCTACTTTATTTGAATTATACTGGGCAGAATCTTAGATGATAC GGGAAAAGCAAAAAACAAACAAACAAACAAACAAACAAACAAAAATCTACAGCATGAGGTGAAATGTGAG AGTTAAGTCGTGCAGACCAAGAGCTGTTTCTTGCTGTCTTTCTCTAACCCCTACAGCACCTTTGGCACTT TTATTGATGATTTCAGAATGTTGTGTGATCCATTTCAACCAACTGGGGGAGAGTTGTATTTTGTTTAAAG AACATTTTCTGATTTTCGAATGTATTTGTTTCTTTGAGGTCATCTTATTGAACTTCTTCCTAACCCGTGT TAACACCACTGAATGTGTAGTTCTTAAGAAAGTGTCATCCTTTTGTACCCCCCACTCCCCAAAAGCATTA CTTTAACTGACAGGGAACATCAGGAATTCTTTATTTCGGCTGTCACTAGGTATTGATGATGGTTATAAAT GTTACAGAGAATAAAAATATATTAGTCTCTTTAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_007901
• Insert Size: 1149 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC049094, AAH49094
• RefSeq Size: 2781 bp
• RefSeq ORF: 1149 bp
• Locus ID: 13609
• UniProt ID: O08530
• Cytogenetics: 3 G1
• Gene Summary: This gene encodes a G-protein-coupled receptor bound by the lysophospholipid, sphingosine 1-phosphate. The gene product functions in endothelial cells and is involved in vascular and heart development. This receptor is highly expressed in T and B lymphocytes, and it plays a role in T cell and B cell export from peripheral lymphoid organs. This protein is bound and downregulated by FTY720, an exogenous immunosuppressant drug studied in mouse disease models for multiple sclerosis in humans. [provided by RefSeq, Jan 2010]