PD1(PDCD1) Mouse Monoclonal Antibody [Clone ID: UMAB199]

CAT#: UM800091

PD-1 (PDCD1) mouse monoclonal antibody,clone UMAB199

 Product Datasheet for 'UM800091'

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USD 468.00

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    • 100 ul

Cited in 2 publications.


Product Data
Clone Name UMAB199
Applications WB, IHC, IF, 10K-CHIP
Recommend Dilution IHC 1:1000, WB 1:500, IF 1:100
Reactivity Human, Mouse, Dog, Rat
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PDCD1 (NP_005009) produced in HEK293T cell.
Isotype IgG2a
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 29.2 kDa
Gene Name Homo sapiens programmed cell death 1 (PDCD1)
Background This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul
Synonyms CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
Reference Data
Protein Families Transmembrane, Druggable Genome
Protein Pathways Cell adhesion molecules (CAMs), T cell receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)