Integrin alpha 3 (ITGA3) Mouse Monoclonal Antibody [Clone ID: IA3]

CAT#: TA353252L

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Mouse monoclonal Anti-Integrin a3 Clone IA3

USD 1,140.00

2 Weeks

    • 500 ug

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Product Data
Clone Name IA3
Recommended Dilution FACS ; IHC ; Functional
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Transfected human breast epithelial cell line MTSV1-7, hygromycin resistant.
Formulation PBS with 0.02% Sodium Azide
Concentration lot specific
Purification Purified by affinity chromatography.
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name integrin subunit alpha 3
Background Integrins are heterodimeric cell surface receptors composed of a and Ã? subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin a3 is found on most cell types. Integrin a3 associates with b1 integrin to form integrin a3b1, which is one of the most abundant keratinocyte integrins and binds laminin 5. IA3 is useful for studies on inhibition of cell-cell adhesion and cell-substrate adhesion.
Synonyms CD49C; GAP-B3; GAPB3; ILNEB; MSK18; VCA-2; VL3A; VLA3a
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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