JNK2(MAPK9) Rabbit Polyclonal Antibody
Rabbit anti-Phospho-MAPK9/MAPK10-T183 Polyclonal Antibody
Product Datasheet for 'TA327595'
|Recommend Dilution||WB: 1:500-1:1000; IHC: 1:50-1:100|
|Reactivity||Human, Mouse, Rat|
|Immunogen||A phospho specific peptide corresponding to residues surrounding T183 of human MAPK9/MAPK10|
|Formulation||Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3|
|Gene Name||mitogen-activated protein kinase 9|
|Background||Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.|
|Protein Families||Protein Kinase, ES Cell Differentiation/IPS, Druggable Genome|
|Protein Pathways||MAPK signaling pathway, ErbB signaling pathway, Wnt signaling pathway, Focal adhesion, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, Neurotrophin signaling pathway, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Adipocytokine signaling pathway, Type II diabetes mellitus, Epithelial cell signaling in Helicobacter pylori infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.